Issels Integrative Immuno-Oncology December 21, 2017  

CAR T Cell Treatment
and Multiple Myeloma

Dear Friend,

CAR T cells, engineered from a patient's own immune cells, have proved to be a valuable weapon in immunotherapy cancer treatment. Now, recent trials demonstrate that CAR T cells may be effective against advanced multiple myeloma.

Global Testing of CAR T Cells

Earlier this year, two groups performed tests on CAR T cells designed to target B-cell maturation antigen (BCMA), a protein specific to myeloma.

• Researchers in China conducted a study in which 33 of 35 patients went into complete remission within two months of treatment.

• A team in Tennessee administered different doses of the CAR T cells to 21 patients. Beyond the first-level dose, patients experienced a 100 percent response rate, with 27 percent achieving a stringent complete response indicating no presence of the disease.

In another encouraging result, patients in both trials who experienced side effects were able to be successfully treated.

How CAR T Cells Fight Cancer

Unlike more traditional forms of cancer treatment, CAR T cells fall under the umbrella of immunotherapy. A patient's individual immune cells are harvested from their blood, and then engineered to target antigens, which are foreign bodies that trigger an immune response.

The CAR T cells are multiplied until they reach a quantity in the billions, and then reintroduced into the patient. According to Dr. James Kochenderfer, lead author of the U.S. study, the key is targeting antigens that aren't expressed in healthy tissues.

Immunotherapy at Issels®: State-of-the-Art Cancer Treatment

For decades, Issels® has been a leader in the healthcare community with our non-toxic, personally-tailored immunotherapy programs. Visit our website to hear success stories from patients with all forms of cancer.

CAR T Cell Treatment's Positive Impact on Multiple Myeloma

Read more interesting articles on the "Issels Cancer Immunotherapy" news/blog posted every Tuesday and Thursday. Check It Out Now »

Immunotherapy: a Miracle Cure for Many

Issels immunotherapy for cancer offers a nontoxic treatment method that is effective and doesn't cause adverse side effects. Our personalized treatment programs have helped patients completely recover, even from aggressive forms of cancer.

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What's happening in Colorectal Cancer Research?

Genomics and immunotherapy for cancer are the main focus points of today's colorectal cancer research. Dr. Wei Zhang and his NFCR-funded team are continuing their promising studies into biomarkers and their use in improving colorectal cancer prognosis and predicting responses to treatment.

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Videos – What Do Patients Say About Their Experience?

Watch videos of patients who share their own experiences at the Issels clinics with you. Listen to their stories and cancer journeys.

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