{"id":1885,"date":"2015-04-01T03:00:03","date_gmt":"2015-04-01T08:00:03","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=1885"},"modified":"2015-03-25T13:44:28","modified_gmt":"2015-03-25T18:44:28","slug":"brain-cancer-immunotherapy-boosted-by-tetanus-vaccine","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2015\/04\/01\/brain-cancer-immunotherapy-boosted-by-tetanus-vaccine\/","title":{"rendered":"Brain Cancer Immunotherapy Boosted by Tetanus Vaccine"},"content":{"rendered":"<figure id=\"attachment_1100\" aria-describedby=\"caption-attachment-1100\" style=\"width: 200px\" class=\"wp-caption alignright\"><a href=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2014\/03\/MP9004021241.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1100\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2014\/03\/MP9004021241-200x300.jpg\" alt=\"Doctor\" width=\"200\" height=\"300\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2014\/03\/MP9004021241-200x300.jpg 200w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2014\/03\/MP9004021241.jpg 683w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><figcaption id=\"caption-attachment-1100\" class=\"wp-caption-text\">Brain Cancer Discoveries<\/figcaption><\/figure>\n<p><a href=\"http:\/\/issels.com\/Vaccines.aspx\">Cancer vaccines<\/a> train the body\u2019s immune system to target and kill cancer cells, often requiring a boost to the patient\u2019s immune power. A recent study has found a surprising teammate for brain cancer vaccines: the tetanus shot.<\/p>\n<p>The same tetanus vaccine used to prevent bacterial infections associated with rusted metal has a powerful effect of activating and alerting the body\u2019s immune system overall. Because of this, the boost from a tetanus shot may be an extremely effective tool in increasing the success of immunotherapy treatments.<\/p>\n<p>Doctors at Duke University Medical Center recently administered <a href=\"http:\/\/www.cancerresearchuk.org\/about-us\/cancer-news\/news-report\/2015-03-12-tetanus-shot-boosts-response-to-experimental-brain-tumour-treatment\">a cancer vaccine trial<\/a> to patients with glioblastoma, an aggressive type of brain tumor. In patients who first received the tetanus shot to awaken their immune response, survival rates increased significantly.<\/p>\n<p>Here\u2019s what the 12-patient trial study found:<\/p>\n<ul>\n<li>Patients given tetanus and cancer vaccines survived 4 to 8 more years, with one patient still surviving. Patients without the tetanus vaccine survived up to 11 months.<\/li>\n<\/ul>\n<ul>\n<li>The tetanus vaccine sounds a warning call to the body\u2019s immune system. This increases the chances that the cancer vaccine will be successfully received by the lymph nodes \u2014 where the cancer vaccine must go to train the immune system.<\/li>\n<\/ul>\n<ul>\n<li>The cytomegalovirus \u2014\u00a0present in most people but inactive \u2014 becomes reactivated in brain cancer cells. The dendritic cells cancer vaccine can identify brain cancer cells by looking for active cytomegalovirus.<\/li>\n<\/ul>\n<p>Researchers hope that the tetanus vaccine can not only be a successful tool to fight glioblastoma brain cancer, but also teach us how to boost other kinds of <a href=\"http:\/\/issels.com\/TreatmentSummary.aspx\">cancer immunotherapy<\/a>.<\/p>\n<p><a href=\"http:\/\/issels.com\/questionnaire\/questionnaire.aspx\">Contact us<\/a> at Issels\u00ae Integrative Immuno-Oncology\u00a0to find out about cancer vaccines and other innovative forms of immunotherapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cancer vaccines train the body\u2019s immune system to target and kill cancer cells, often requiring a boost to the patient\u2019s immune power. A recent study has found a surprising teammate for brain cancer vaccines: the tetanus shot. The same tetanus vaccine used to prevent bacterial infections associated with rusted metal has a powerful effect of &hellip; <a href=\"https:\/\/issels.com\/blog\/2015\/04\/01\/brain-cancer-immunotherapy-boosted-by-tetanus-vaccine\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Brain Cancer Immunotherapy Boosted by Tetanus Vaccine<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,216],"tags":[411,259,412],"class_list":["post-1885","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-immunotherapy","tag-brain-cancer","tag-fighting-cancer","tag-tetanus"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1885","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=1885"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1885\/revisions"}],"predecessor-version":[{"id":1886,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1885\/revisions\/1886"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=1885"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=1885"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=1885"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}