{"id":1951,"date":"2015-05-11T03:00:58","date_gmt":"2015-05-11T08:00:58","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=1951"},"modified":"2015-05-09T13:44:52","modified_gmt":"2015-05-09T18:44:52","slug":"precision-cancer-treatments-use-genomics-for-tumor-targeting","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2015\/05\/11\/precision-cancer-treatments-use-genomics-for-tumor-targeting\/","title":{"rendered":"Precision Cancer Treatments Use Genomics for Tumor Targeting"},"content":{"rendered":"<figure id=\"attachment_1952\" aria-describedby=\"caption-attachment-1952\" style=\"width: 212px\" class=\"wp-caption alignright\"><a href=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/cytokine.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1952\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/cytokine-212x300.jpg\" alt=\"Genetic Profiling\" width=\"212\" height=\"300\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/cytokine-212x300.jpg 212w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/cytokine.jpg 225w\" sizes=\"auto, (max-width: 212px) 100vw, 212px\" \/><\/a><figcaption id=\"caption-attachment-1952\" class=\"wp-caption-text\">Genetic Profiling<\/figcaption><\/figure>\n<p><span style=\"font-family: 'Arial','sans-serif';\">While <a href=\"http:\/\/www.issels.com\/newissels\/\" target=\"_blank\">cancer treatments<\/a> continue to become more effective, physicians are still, all too often, faced with cases where a tumor fails to respond to any methods. Researchers are now optimistic about the possibility of <a href=\"http:\/\/www.pressreader.com\/usa\/the-washington-post\/20150310\/282707635532209\/TextView\" target=\"_blank\">genetic profiling<\/a> as a way to pinpoint vulnerable\u00a0treatment\u00a0options\u00a0in an otherwise stubborn tumor.<\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\">Oncologist Michael Pishvaian of Georgetown Lombardi Comprehensive Cancer Center compares locating the source of a tumor&#8217;s growth to &#8220;looking for a needle in a haystack.&#8221; The problem is that a cancer cell may hold <a href=\"https:\/\/issels.com\/blog\/2014\/06\/02\/what-is-the-immunobiologic-core-treatment\/\" target=\"_blank\">hundreds of abnormally behaving genes<\/a>, but it&#8217;s likely that only a few of them are actually fueling the tumor.<\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\">Dr. Pishvaian has first-hand experience with tumor profiling. In June 2013, he was treating a patient named Jen Morey for colon cancer using a conventional chemotherapy protocol. Unfortunately, after a couple of months the tumor was still growing at a rapid rate.<\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\">Faced with this roadblock, Dr. Pishvaian ordered a tumor profile test in an attempt to discover why treatment wasn&#8217;t working. He was astonished when the results indicated a genetic mutation found almost exclusively in breast cancer.\u00a0<\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\">Morey began undergoing treatment with a drug commonly used to target breast cancer gene mutations. Her condition quickly stabilized, and the new protocol was easier to tolerate because it attacks only cancer cells. A CT scan in December showed that the tumor has remained stable, and Morey was able to return to her critical-care nursing job in late January.<\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\">Our <a href=\"http:\/\/www.issels.com\/newissels\/treatment-summary\/\" target=\"_blank\">natural immuno-oncology treatments<\/a> also use a personalized approach, including genomic testing, to create the most effective non-toxic protocols. Visit our website to learn more about our innovative cancer treatments.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>While cancer treatments continue to become more effective, physicians are still, all too often, faced with cases where a tumor fails to respond to any methods. Researchers are now optimistic about the possibility of genetic profiling as a way to pinpoint vulnerable\u00a0treatment\u00a0options\u00a0in an otherwise stubborn tumor. Oncologist Michael Pishvaian of Georgetown Lombardi Comprehensive Cancer Center &hellip; <a href=\"https:\/\/issels.com\/blog\/2015\/05\/11\/precision-cancer-treatments-use-genomics-for-tumor-targeting\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Precision Cancer Treatments Use Genomics for Tumor Targeting<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203],"tags":[430,292],"class_list":["post-1951","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","tag-cancer-predisposition","tag-genetics"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=1951"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1951\/revisions"}],"predecessor-version":[{"id":1953,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/1951\/revisions\/1953"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=1951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=1951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=1951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}