{"id":2524,"date":"2016-11-08T03:19:55","date_gmt":"2016-11-08T08:19:55","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2524"},"modified":"2016-11-08T08:03:28","modified_gmt":"2016-11-08T13:03:28","slug":"genetic-advances-made-in-prostate-cancer-identification","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2016\/11\/08\/genetic-advances-made-in-prostate-cancer-identification\/","title":{"rendered":"Genetic Advances Made in Prostate Cancer Identification"},"content":{"rendered":"<p><a href=\"http:\/\/issels.com\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">Prostate cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> affects approximately 15 percent of males in their lifetime, and is second only to skin cancer. Recent identification of <\/span><a href=\"http:\/\/www.news.cornell.edu\/stories\/2016\/10\/gene-drives-aggressive-prostate-cancer-identified\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">an overactive gene that accelerates prostate cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> could lead to development of a more effective treatment.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">Prostate Cancer Evolves Beyond Drugs<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">Most prostate tumors are caused by a form of cancer called adenocarcinoma. In advanced stages, adenocarcinoma is treated with drugs that block androgens, the male hormones that fuel the tumor. Unfortunately, the tumors have evolved into a more aggressive, androgen-resistant form called <\/span><a href=\"https:\/\/issels.com\/blog\/2015\/08\/25\/which-type-of-prostate-cancer-do-you-have-scientists-find-5-types\/\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">neuroendocrine prostate cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\">.<\/span><\/p>\n<figure id=\"attachment_885\" aria-describedby=\"caption-attachment-885\" style=\"width: 190px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-885\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/11\/MP9004252641-190x300.jpg\" alt=\"Prostate Cancer Identification \" width=\"190\" height=\"300\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/11\/MP9004252641-190x300.jpg 190w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/11\/MP9004252641.jpg 651w\" sizes=\"auto, (max-width: 190px) 100vw, 190px\" \/><figcaption id=\"caption-attachment-885\" class=\"wp-caption-text\">Prostate Cancer Identification<\/figcaption><\/figure>\n<p><span style=\"font-family: 'Arial',sans-serif;\">A cross-disciplinary team supported by the Prostate Cancer Foundation discovered a gene known as N-Myc that appears to be the driver behind the change to the more aggressive form. While N-Myc is not usually found in prostate cancer, it has been known to occur in other forms such as neuroblastoma, a rare cancer of the nervous system found in children.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">A Pathway to New Treatment Methods<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">When N-Myc goes into overdrive, it teams up with a protein called EZH2 to block the tumor&#8217;s androgen signaling and &#8220;flips the switch&#8221; on the molecular program that leads to the more aggressive neuroendocrine form. Dr. Jonathan W. Simons, president and CEO of the Prostate Cancer Foundation, calls this a &#8220;game-changing&#8221; discovery that can enable development of more successful treatments.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">Personalized, Non-Toxic Treatments for Prostate Cancer<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">Issels\u00ae offers a wide range of <\/span><a href=\"http:\/\/issels.com\/treatment-summary\/\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">Immunotherapy for Cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> protocols, including vaccines and NK cells that have been used to treat patients with prostate cancer, melanoma, leukemia and all other forms. <\/span><a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">Contact us today<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> to find out how Immunotherapy for Cancer at Issels\u00ae can help you or your loved one.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prostate cancer affects approximately 15 percent of males in their lifetime, and is second only to skin cancer. Recent identification of an overactive gene that accelerates prostate cancer could lead to development of a more effective treatment. Prostate Cancer Evolves Beyond Drugs Most prostate tumors are caused by a form of cancer called adenocarcinoma. In &hellip; <a href=\"https:\/\/issels.com\/blog\/2016\/11\/08\/genetic-advances-made-in-prostate-cancer-identification\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Genetic Advances Made in Prostate Cancer Identification<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,205,538],"tags":[448,282,273],"class_list":["post-2524","post","type-post","status-publish","format-standard","hentry","category-cancer-research","category-immuno-oncology","category-immunotherapy-for-cancer","tag-advances-in-cancer-treatment","tag-cancer-news","tag-prostate-cancer"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2524"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2524\/revisions"}],"predecessor-version":[{"id":2525,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2524\/revisions\/2525"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}