{"id":2611,"date":"2017-02-07T03:00:43","date_gmt":"2017-02-07T08:00:43","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2611"},"modified":"2017-01-19T10:39:31","modified_gmt":"2017-01-19T15:39:31","slug":"some-immunotherapy-drugs-may-cause-heart-damage-but-there-is-the-issels-safe-alternative","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/02\/07\/some-immunotherapy-drugs-may-cause-heart-damage-but-there-is-the-issels-safe-alternative\/","title":{"rendered":"Some Immunotherapy Drugs May Cause Heart Damage But There Is the Issels Safe Alternative"},"content":{"rendered":"<figure id=\"attachment_2532\" aria-describedby=\"caption-attachment-2532\" style=\"width: 200px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2532\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_27130631_s-2015-350x227.jpg\" width=\"200\" height=\"130\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_27130631_s-2015-350x227.jpg 350w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_27130631_s-2015.jpg 500w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><figcaption id=\"caption-attachment-2532\" class=\"wp-caption-text\">New Immunotherapy Drugs<\/figcaption><\/figure>\n<p><span style=\"font-family: 'Arial',sans-serif;\">New <\/span><a href=\"http:\/\/www.nbcnews.com\/health\/cancer\/new-cancer-drugs-may-damage-heart-n677071\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">immunotherapy drugs<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> on the market have shown tremendous benefits in <\/span><a href=\"http:\/\/issels.com\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">battling cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\">, but a potentially serious side effect has come to light recently. Some of these drugs, especially when used in combination, may cause heart damage.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">Putting the Immune System in Overdrive<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">In November 2016 the New England Journal of Medicine published a report from a team of experts led by Dr. Javid Moslehi of Vanderbilt University. It involved two melanoma patients who died two weeks after their initial doses of Opdivo and Yervoy, manufactured by pharmaceutical giant Bristol-Myers Squibb.<\/span><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">Opdivo and Yervoy are part of the class of drugs known as <\/span><a href=\"https:\/\/issels.com\/blog\/2016\/08\/16\/immune-checkpoint-inhibitors-the-role-they-play-in-cancer-immunotherapy\/\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">checkpoint inhibitors<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> that boost the immune system&#8217;s ability to fight cancer cells. In some rare cases, it appears that the immune system also begins attacking the heart and other muscles.<\/span><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">Patient safety records at Bristol-Myers revealed that 18 patients out of 20,594 people receiving one or both drugs had experienced heart inflammation (for a rate of 0.09 percent). The rate increased for patients using both drugs, but it was still less than one percent.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">Doctors are Cautious but Optimistic<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">According to Dr. Jeffrey Sosman of Chicago&#8217;s Northwestern University, who treated both patients in the report, overstimulation of the immune system was a known possibility. Many doctors believe drug combos are still the best option for effective treatment, but they are stressing that patients need to be informed of the risk and monitored closely.<\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial',sans-serif;\">Issels\u00ae Has Decades of Experience with Non-Toxic, Safe Immunotherapy for Cancer<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial',sans-serif;\">Our clinic&#8217;s namesake, renowned cancer specialist Dr. Josef Issels, pioneered <\/span><a href=\"https:\/\/issels.com\/blog\/2016\/12\/08\/the-issels-story-a-focus-on-immunotherapy\/\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">integrative methods of immunotherapy for cancer<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> dating back to the mid-20th century. <\/span><a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\" target=\"_blank\"><span style=\"font-family: 'Arial',sans-serif;\">Contact us<\/span><\/a><span style=\"font-family: 'Arial',sans-serif;\"> for more information about our safe non-toxic immunotherapy and cancer vaccines.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>New immunotherapy drugs on the market have shown tremendous benefits in battling cancer, but a potentially serious side effect has come to light recently. Some of these drugs, especially when used in combination, may cause heart damage. Putting the Immune System in Overdrive In November 2016 the New England Journal of Medicine published a report &hellip; <a href=\"https:\/\/issels.com\/blog\/2017\/02\/07\/some-immunotherapy-drugs-may-cause-heart-damage-but-there-is-the-issels-safe-alternative\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Some Immunotherapy Drugs May Cause Heart Damage But There Is the Issels Safe Alternative<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,216,538],"tags":[259,219,573],"class_list":["post-2611","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-immunotherapy","category-immunotherapy-for-cancer","tag-fighting-cancer","tag-immunotherapy","tag-integrative-cancer-methods"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2611"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2611\/revisions"}],"predecessor-version":[{"id":2612,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2611\/revisions\/2612"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}