{"id":2620,"date":"2017-02-23T03:00:10","date_gmt":"2017-02-23T08:00:10","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2620"},"modified":"2017-02-02T13:57:32","modified_gmt":"2017-02-02T18:57:32","slug":"blocking-cystine-may-starve-a-hard-to-treat-breast-cancer","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/02\/23\/blocking-cystine-may-starve-a-hard-to-treat-breast-cancer\/","title":{"rendered":"Blocking Cystine May Starve a Hard to Treat Breast Cancer"},"content":{"rendered":"<figure id=\"attachment_1977\" aria-describedby=\"caption-attachment-1977\" style=\"width: 200px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1977\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/Depositphotos_35215291_xs-262x300.jpg\" alt=\"A Unique Perspective\" width=\"200\" height=\"229\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/Depositphotos_35215291_xs-262x300.jpg 262w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/05\/Depositphotos_35215291_xs.jpg 324w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><figcaption id=\"caption-attachment-1977\" class=\"wp-caption-text\">Block Cancer<\/figcaption><\/figure>\n<p>Cancer cells have a high-powered metabolism that demands a <a href=\"https:\/\/today.duke.edu\/2016\/11\/breast-cancer-cells-starve-cystine\">steady stream of nutrients<\/a> for fuel. Scientists may have discovered a way to &#8220;starve&#8221; a hard-to-treat form of <a href=\"http:\/\/issels.com\/\">breast cancer<\/a> by depriving the cells of a crucial substance.<\/p>\n<p><strong>Feed a Cold, Starve Cancer?<\/strong><\/p>\n<p>Triple negative breast cancer (TNBC) is a particularly aggressive and treatment-resistant form. In a study performed at Duke University, researchers found that the cells have an &#8220;addiction&#8221; to a nutrient called cystine, and deprivation causes them to die off quickly.<\/p>\n<p>Further examination showed that the addiction is triggered by a mechanism used by the cells to migrate to other parts of the body, a process known as <a href=\"https:\/\/issels.com\/blog\/2015\/11\/10\/what-to-understand-about-metastatic-cancer\/\">metastasis<\/a>. According to Jen-Tsan Ashley Chi, associate professor at Duke University School of Medicine and lead author of the study, the metastasized cells are the primary target of treatment.<\/p>\n<p><strong>What&#8217;s Next?<\/strong><\/p>\n<p>Chi&#8217;s group had previously published a study showing that the cells in a stubborn form of kidney cancer are also subject to the cystine addiction. The next step is to test cystine-blocking molecules on tumors and look for biomarkers that will signal cancer cells that are receptive to the treatment.<\/p>\n<p>As Chi explains, tumor cells use this programming to move rapidly around the body. The researchers&#8217; goal is to take advantage of the same process for a cure.<\/p>\n<p><strong>State-of-the-Art Immunotherapy for Cancer at Issels\u00ae<\/strong><\/p>\n<p>Our personally-tailored <a href=\"http:\/\/issels.com\/treatment-summary\/\">immunotherapy for cancer<\/a> treatments are developed using genome testing and other cutting edge methods. <a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\">Contact us<\/a> for testimonials from patients who have been successfully treated for all forms of cancer, ranging from lung cancer to melanoma to leukemia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cancer cells have a high-powered metabolism that demands a steady stream of nutrients for fuel. Scientists may have discovered a way to &#8220;starve&#8221; a hard-to-treat form of breast cancer by depriving the cells of a crucial substance. Feed a Cold, Starve Cancer? Triple negative breast cancer (TNBC) is a particularly aggressive and treatment-resistant form. In &hellip; <a href=\"https:\/\/issels.com\/blog\/2017\/02\/23\/blocking-cystine-may-starve-a-hard-to-treat-breast-cancer\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Blocking Cystine May Starve a Hard to Treat Breast Cancer<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,473,203,538],"tags":[481,539,259],"class_list":["post-2620","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-breast-cancer","category-cancer-research","category-immunotherapy-for-cancer","tag-breast-cancer-treatment","tag-cancer-immunotherapy","tag-fighting-cancer"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2620"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2620\/revisions"}],"predecessor-version":[{"id":2621,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2620\/revisions\/2621"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}