{"id":2625,"date":"2017-02-21T03:06:16","date_gmt":"2017-02-21T08:06:16","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2625"},"modified":"2017-02-21T05:57:46","modified_gmt":"2017-02-21T10:57:46","slug":"could-the-x-chromosome-hold-a-key-to-cancer-incidence","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/02\/21\/could-the-x-chromosome-hold-a-key-to-cancer-incidence\/","title":{"rendered":"Could the X Chromosome Hold a Key to Cancer Incidence?"},"content":{"rendered":"
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New Cancer Research<\/figcaption><\/figure>\n

High school biology teaches that the Y chromosome is what distinguishes males from females, who have two X chromosomes. Cancer researchers are exploring the possibility that the additional X chromosome may hold a key to why women have a lower incidence of <\/span>cancer<\/span><\/a> than men.<\/span><\/p>\n

Genetic Gender Bias?<\/span><\/strong><\/p>\n

The so-called <\/span>“male bias”<\/span><\/a> runs across all types of cancer. In the past it was thought to be caused by men’s greater exposure to environmental factors such as <\/span>cigarette smoke<\/span><\/a> and chemicals, but that didn’t explain a similar bias in juvenile cancers like pediatric leukemia.<\/span><\/p>\n

According to Dr. Andrew Lane of Boston’s Dana-Farber Cancer Institute, lead author of the study, everyone carries tumor suppressor genes that protect cells from cancer. When cancer develops, these genes lose functionality.<\/span><\/p>\n

Strength in Numbers<\/span><\/strong><\/p>\n

The study revealed the genes that were mutated more frequently in male cancers occurred on the X chromosome. While this sounds counterintuitive, there’s more to the story.<\/span><\/p>\n

One copy of the X chromosome is shut down in all cells, a process known as X inactivation. But approximately 50 of the 800 genes on the X chromosome are spared, leaving women with two sets of those particular genes. As a result, any cancer that develops must mutate twice as many of the genes in women as in men.<\/span><\/p>\n

Genomic Testing and Immunotherapy for Cancer<\/span><\/strong><\/p>\n

Each patient’s cancer is unique, which is why genomic testing is one of the special methods we use at Issels\u00ae. <\/span>Contact us<\/span><\/a> for more information about our personally tailored <\/span>immunotherapy for cancer<\/span><\/a> treatments that destroy cancer cells while strengthening your body’s own natural defenses.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

High school biology teaches that the Y chromosome is what distinguishes males from females, who have two X chromosomes. Cancer researchers are exploring the possibility that the additional X chromosome may hold a key to why women have a lower incidence of cancer than men. Genetic Gender Bias? The so-called “male bias” runs across all … Continue reading Could the X Chromosome Hold a Key to Cancer Incidence?<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,205,216,538,2],"tags":[539,327,292,516],"class_list":["post-2625","post","type-post","status-publish","format-standard","hentry","category-cancer-research","category-immuno-oncology","category-immunotherapy","category-immunotherapy-for-cancer","category-news","tag-cancer-immunotherapy","tag-gene-therapy","tag-genetics","tag-genomic-testing"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2625","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2625"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2625\/revisions"}],"predecessor-version":[{"id":2628,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2625\/revisions\/2628"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}