{"id":2636,"date":"2017-03-09T02:10:16","date_gmt":"2017-03-09T07:10:16","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2636"},"modified":"2017-03-07T22:14:44","modified_gmt":"2017-03-08T03:14:44","slug":"nanodiscs-may-personalize-immunotherapy-for-cancer-in-the-near-future","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/03\/09\/nanodiscs-may-personalize-immunotherapy-for-cancer-in-the-near-future\/","title":{"rendered":"Nanodiscs May Personalize Immunotherapy for Cancer in the Near Future"},"content":{"rendered":"<figure id=\"attachment_2454\" aria-describedby=\"caption-attachment-2454\" style=\"width: 250px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2454 size-thumbnail\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/08\/Depositphotos_14563449_s-2015-250x150.jpg\" alt=\"Training Your Immune System to Fight Off Cancer For You!\" width=\"250\" height=\"150\" \/><figcaption id=\"caption-attachment-2454\" class=\"wp-caption-text\">Training Your Immune System to Fight Off Cancer For You!<\/figcaption><\/figure>\n<p>One of the highlights of <a href=\"http:\/\/issels.com\/\">immunotherapy for cancer<\/a> is that the protocols are personally tailored to address your individual needs. A research team at the University of Michigan recently developed a way to <a href=\"http:\/\/www.fiercebiotech.com\/research\/vaccine-nanodiscs-could-personalize-cancer-immunotherapy\">customize cancer vaccines<\/a> that holds promise for both current treatment and long-term immunity.<\/p>\n<p><strong>&#8220;Training&#8221; the Immune System<\/strong><\/p>\n<p><a href=\"https:\/\/issels.com\/blog\/2016\/10\/04\/immunotherapy-a-doctors-fundamental-change-in-treating-cancer\/\">Immunotherapy for cancer<\/a> focuses on helping your own immune system battle cancer cells. The vaccine created by the University of Michigan team uses synthetic high-density lipoproteins called nanodiscs to train the immune system to recognize and attack cancer cells.<\/p>\n<p>Nanodiscs use patient-specific genetic mutations, or tumor neoantigens, to trigger production of T-cells by the immune system. The T-cells then use the genetic material in the nanodiscs to target the cancer cells.<\/p>\n<p>The study involved treating mice suffering from melanoma and colon cancer with a combination of <a href=\"https:\/\/issels.com\/blog\/2016\/08\/16\/immune-checkpoint-inhibitors-the-role-they-play-in-cancer-immunotherapy\/\">checkpoint inhibitors<\/a> and the nanodisc vaccine. Not only were most of the tumors eliminated, the mice remained tumor-free after the same cancer cells were reintroduced into their systems after 70 days.<\/p>\n<p><strong>University of Michigan Goes All-In on Nanodisc Research<\/strong><\/p>\n<p>Encouraged by the results of the test, the University of Michigan has created a biotech company named EVOQ Therapeutics to concentrate on developing and refining the nanodisc vaccine. Plans are to conduct further studies on animals before moving into clinical trials.<\/p>\n<p><strong>Issels\u00ae: Blazing the Immunotherapy for Cancer Trail<\/strong><\/p>\n<p><a href=\"http:\/\/issels.com\/cancer-vaccines\/\">Cancer vaccines<\/a> are just one of the innovative non-toxic treatments we employ at Issels\u00ae. <a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\">Visit our website<\/a> to learn more about our specialized testing methods and individualized integrative programs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One of the highlights of immunotherapy for cancer is that the protocols are personally tailored to address your individual needs. A research team at the University of Michigan recently developed a way to customize cancer vaccines that holds promise for both current treatment and long-term immunity. &#8220;Training&#8221; the Immune System Immunotherapy for cancer focuses on &hellip; <a href=\"https:\/\/issels.com\/blog\/2017\/03\/09\/nanodiscs-may-personalize-immunotherapy-for-cancer-in-the-near-future\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Nanodiscs May Personalize Immunotherapy for Cancer in the Near Future<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,216],"tags":[209,539,212],"class_list":["post-2636","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-immunotherapy","tag-alternative-cancer-treatment","tag-cancer-immunotherapy","tag-cancer-research"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2636"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2636\/revisions"}],"predecessor-version":[{"id":2637,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2636\/revisions\/2637"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}