{"id":2666,"date":"2017-04-18T02:08:05","date_gmt":"2017-04-18T07:08:05","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2666"},"modified":"2017-04-14T17:10:12","modified_gmt":"2017-04-14T22:10:12","slug":"new-t-cell-tracking-may-improve-immunotherapy-treatments","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/04\/18\/new-t-cell-tracking-may-improve-immunotherapy-treatments\/","title":{"rendered":"New T Cell Tracking May Improve Immunotherapy Treatments"},"content":{"rendered":"<figure id=\"attachment_2541\" aria-describedby=\"caption-attachment-2541\" style=\"width: 350px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2541 size-medium\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_43643757_m-350x239.jpg\" alt=\"Another Step in Stopping Cancer\" width=\"350\" height=\"239\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_43643757_m-350x239.jpg 350w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_43643757_m-768x524.jpg 768w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_43643757_m-1024x699.jpg 1024w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/11\/Depositphotos_43643757_m.jpg 1711w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><figcaption id=\"caption-attachment-2541\" class=\"wp-caption-text\">New T Cell Tracking May Improve Immunotherapy Treatments<\/figcaption><\/figure>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">T cells are in the front line of your immune system, multiplying rapidly to attack invading cells throughout your body. <\/span><\/span><a href=\"http:\/\/issels.com\/\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">Immunotherapy for cancer<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\"> took a big step forward with a study that found <\/span><\/span><a href=\"http:\/\/www.medicalnewstoday.com\/articles\/316077.php\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">ways to track T cells<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\"> in order to harness their specific tumor-fighting abilities.<\/span><\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Finding a Needle in a Haystack<\/span><\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Adoptive T cell transfer is a method of treatment in which <\/span><\/span><a href=\"https:\/\/issels.com\/blog\/2017\/02\/09\/strategic-t-cells-use-may-be-the-key-to-effective-cancer-treatment\/\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">T cells<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\"> are harvested from a patient&#8217;s body and &#8220;groomed&#8221; to target cancer cells. They were then multiplied and placed back in the patient&#8217;s system where they could attack the tumor.<\/span><\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Unfortunately, there are a couple of roadblocks to this process. It&#8217;s difficult to know which of the thousands of different types of T cells are most effective against cancer, and cloning the cells can dilute or alter the tumor-killing properties of the originals.<\/span><\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Solving the Identification Problem<\/span><\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Researchers at Seattle&#8217;s Fred Hutchinson Cancer Research Center have discovered a process to help solve the former problem. A method called high throughput T cell receptor sequencing allowed the scientists to tag each T cell receptor with a &#8220;barcode,&#8221; enabling them to be tracked throughout the body.<\/span><\/span><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">The team gained valuable data when they applied the method to 10 patients with <\/span><\/span><a href=\"https:\/\/issels.com\/blog\/2015\/11\/10\/what-to-understand-about-metastatic-cancer\/\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">metastatic melanoma<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">. Trials are now underway in search of more effective ways to extract and multiply T cells.<\/span><\/span><\/p>\n<p><strong><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">Immunotherapy for Cancer: Boosting Your Body&#8217;s Natural Defenses<\/span><\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\">For decades, Issels\u00ae has been a pioneer in the use of vaccines, NK cells and other non-toxic <\/span><\/span><a href=\"https:\/\/issels.com\/blog\/2017\/03\/28\/immunotherapy-experts-share-opinions-on-the-future-of-treatments\/\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">immunotherapy for cancer<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\"> treatments. <\/span><\/span><a href=\"http:\/\/issels.com\/treatment-summary\/\" target=\"_blank\"><span style=\"font-family: 'Arial','sans-serif';\"><u><span style=\"color: #0000ff;\">Visit our website<\/span><\/u><\/span><\/a><span style=\"font-family: 'Arial','sans-serif';\"><span style=\"color: #000000;\"> to learn more about our individually tailored programs.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>T cells are in the front line of your immune system, multiplying rapidly to attack invading cells throughout your body. Immunotherapy for cancer took a big step forward with a study that found ways to track T cells in order to harness their specific tumor-fighting abilities. Finding a Needle in a Haystack Adoptive T cell &hellip; <a href=\"https:\/\/issels.com\/blog\/2017\/04\/18\/new-t-cell-tracking-may-improve-immunotherapy-treatments\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">New T Cell Tracking May Improve Immunotherapy Treatments<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,580],"tags":[224,219,531,356],"class_list":["post-2666","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-cancer-treatment","tag-cancer-treatment","tag-immunotherapy","tag-immunotherapy-for-cancer","tag-t-cells"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2666","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2666"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2666\/revisions"}],"predecessor-version":[{"id":2667,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2666\/revisions\/2667"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2666"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2666"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}