{"id":2672,"date":"2017-04-25T02:23:02","date_gmt":"2017-04-25T07:23:02","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2672"},"modified":"2017-04-21T13:25:25","modified_gmt":"2017-04-21T18:25:25","slug":"is-there-a-link-between-gut-bacteria-and-an-immunotherapy-response","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/04\/25\/is-there-a-link-between-gut-bacteria-and-an-immunotherapy-response\/","title":{"rendered":"Is There a Link Between Gut Bacteria and an Immunotherapy Response?"},"content":{"rendered":"
\"Questions
Questions on How Immunotherapy Will Work for You?<\/figcaption><\/figure>\n

Could the path to fighting cancer go through your stomach? Researchers have found a surprising link between <\/span><\/span>immunotherapy for cancer<\/span><\/a> and the <\/span><\/span>bacteria found in your gut<\/span><\/a>.<\/span><\/span><\/p>\n

The Varied Responses to Immunotherapy<\/span><\/span><\/strong><\/p>\n

While scientists had previously made the connection with mice, a team at the University of Texas MD Anderson Cancer Center recently made a breakthrough with the first study involving humans. The subjects included 233 patients with advanced melanoma.<\/span><\/span><\/p>\n

A subset of 43 patients was on <\/span><\/span>checkpoint inhibitors<\/span><\/a>, one of the primary methods of immunotherapy for cancer. Out of this group, 30 responded to the treatment while 13 did not.<\/span><\/span><\/p>\n

What made the difference? The researchers discovered that the 30 patients who responded had a wider variety of <\/span><\/span>gut bacteria<\/span><\/a>, particularly a specific type called Clostridiales, along with a higher concentration of the immune cells that fight cancer.<\/span><\/span><\/p>\n

Strengthening the Immune System<\/span><\/span><\/strong><\/p>\n

According to Fred Ramsdell, vice president of research at the Parker Institute for Cancer Immunotherapy, it’s likely that exposure to a greater amount of bacteria during your lifetime results in a more robust immune system. Exactly why this happens is still a puzzle for now.<\/span><\/span><\/p>\n

Experts are optimistic that this information will eventually be used to more effectively target patients who will respond to immunotherapy treatments. A clinical trial focusing on the microbiome is planned for later this year. <\/span><\/span><\/p>\n

Immunotherapy for Cancer: The Issels\u00ae Approach<\/span><\/span><\/strong><\/p>\n

Our namesake, <\/span><\/span>Dr. Josef M. Issels<\/span><\/a>, pioneered non-toxic immunotherapy treatments and we carry on his legacy today. <\/span><\/span>Contact us<\/span><\/a> for more information about our individually tailored programs that are created to meet your individual needs.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Could the path to fighting cancer go through your stomach? Researchers have found a surprising link between immunotherapy for cancer and the bacteria found in your gut. The Varied Responses to Immunotherapy While scientists had previously made the connection with mice, a team at the University of Texas MD Anderson Cancer Center recently made a … Continue reading Is There a Link Between Gut Bacteria and an Immunotherapy Response?<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,580,537,205,216,538],"tags":[224,531],"class_list":["post-2672","post","type-post","status-publish","format-standard","hentry","category-cancer-research","category-cancer-treatment","category-cancer-vaccine","category-immuno-oncology","category-immunotherapy","category-immunotherapy-for-cancer","tag-cancer-treatment","tag-immunotherapy-for-cancer"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2672"}],"version-history":[{"count":1,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2672\/revisions"}],"predecessor-version":[{"id":2674,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2672\/revisions\/2674"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2672"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2672"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}