{"id":2946,"date":"2017-10-25T02:25:53","date_gmt":"2017-10-25T07:25:53","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=2946"},"modified":"2017-10-15T17:05:13","modified_gmt":"2017-10-15T22:05:13","slug":"multiple-myeloma-patients-react-positively-to-car-t-cells-treatment","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2017\/10\/25\/multiple-myeloma-patients-react-positively-to-car-t-cells-treatment\/","title":{"rendered":"Multiple Myeloma Patients React Positively to CAR T Cells Treatment"},"content":{"rendered":"<figure id=\"attachment_2454\" aria-describedby=\"caption-attachment-2454\" style=\"width: 350px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2454\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/08\/Depositphotos_14563449_s-2015-350x234.jpg\" alt=\"New Discoveries for Making Cancer Easier to Bear Are Sprouting Up! \" width=\"350\" height=\"234\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/08\/Depositphotos_14563449_s-2015-350x234.jpg 350w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2016\/08\/Depositphotos_14563449_s-2015.jpg 499w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><figcaption id=\"caption-attachment-2454\" class=\"wp-caption-text\">New Discoveries for Making Cancer Easier to Bear Are Sprouting Up!<\/figcaption><\/figure>\n<p>CAR T cells, engineered from a patient&#8217;s own immune cells, have proved to be a valuable weapon in <a href=\"http:\/\/issels.com\" target=\"_blank\" rel=\"noopener\">immunotherapy cancer treatment<\/a>. Now, recent trials demonstrate that CAR T cells may be effective against <a href=\"https:\/\/www.cancer.gov\/news-events\/cancer-currents-blog\/2017\/car-t-cell-multiple-myeloma\" target=\"_blank\" rel=\"noopener\">advanced multiple myeloma<\/a>.<\/p>\n<p><strong>Global Testing of CAR T Cells<\/strong><\/p>\n<p>Earlier this year, two groups performed tests on <a href=\"https:\/\/issels.com\/blog\/2017\/08\/25\/cancer-treatment-using-car-t-cells-excites-researchers-with-results\/\" target=\"_blank\" rel=\"noopener\">CAR T cells<\/a> designed to target B-cell maturation antigen (BCMA), a protein specific to myeloma.<\/p>\n<ul>\n<li>Researchers in China conducted a study in which 33 of 35 patients went into complete remission within two months of treatment.<\/li>\n<li>A team in Tennessee administered different doses of the CAR T cells to 21 patients. Beyond the first-level dose, patients experienced a 100 percent response rate, with 27 percent achieving a stringent complete response indicating no presence of the disease.<\/li>\n<\/ul>\n<p>In another encouraging result, patients in both trials who experienced side effects were able to be successfully treated.<\/p>\n<p><strong>How CAR T Cells Fight Cancer<\/strong><\/p>\n<p>Unlike more traditional forms of cancer treatment, CAR T cells fall under the umbrella of <a href=\"https:\/\/issels.com\/blog\/2017\/04\/27\/transformative-impact-of-immunotherapy-tops-cancer-news\/\" target=\"_blank\" rel=\"noopener\">immunotherapy<\/a>. A patient&#8217;s individual immune cells are harvested from their blood, then engineered to target antigens, which are foreign bodies that trigger an immune response.<\/p>\n<p>The CAR T cells are multiplied until they reach a quantity in the billions, then reintroduced into the patient. According to Dr. James Kochenderfer, lead author of the U.S. study, the key is targeting antigens that aren&#8217;t expressed in healthy tissues.<\/p>\n<p><strong>Immunotherapy at Issels\u00ae: State-of-the-Art Cancer Treatment<\/strong><\/p>\n<p>For decades, Issels\u00ae has been a leader in the healthcare community with our non-toxic, <a href=\"https:\/\/issels.com\/blog\/2017\/08\/18\/precision-medicine-may-allow-specialized-treatment-targeting\/\" target=\"_blank\" rel=\"noopener\">personally-tailored immunotherapy programs<\/a>. Visit our website to hear <a href=\"https:\/\/issels.com\/blog\/2017\/06\/02\/our-patient-testimonials-give-an-insiders-view-of-our-cancer-treatments\/\" target=\"_blank\" rel=\"noopener\">success stories from patients<\/a> with all forms of cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CAR T cells, engineered from a patient&#8217;s own immune cells, have proved to be a valuable weapon in immunotherapy cancer treatment. Now, recent trials demonstrate that CAR T cells may be effective against advanced multiple myeloma. Global Testing of CAR T Cells Earlier this year, two groups performed tests on CAR T cells designed to &hellip; <a href=\"https:\/\/issels.com\/blog\/2017\/10\/25\/multiple-myeloma-patients-react-positively-to-car-t-cells-treatment\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Multiple Myeloma Patients React Positively to CAR T Cells Treatment<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,231,580,1],"tags":[384,260,635,633,634],"class_list":["post-2946","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-survivors","category-cancer-treatment","category-uncategorized","tag-alternative-cancer-treatment-center","tag-alternative-medicine","tag-clinical-trials","tag-positive-treatment-outcomes","tag-trial-treatments"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=2946"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2946\/revisions"}],"predecessor-version":[{"id":2956,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/2946\/revisions\/2956"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=2946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=2946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=2946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}