{"id":3094,"date":"2018-01-17T03:37:16","date_gmt":"2018-01-17T08:37:16","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3094"},"modified":"2018-01-05T16:39:25","modified_gmt":"2018-01-05T21:39:25","slug":"treatment-uses-patients-own-immune-cells-to-fight-cancer","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/01\/17\/treatment-uses-patients-own-immune-cells-to-fight-cancer\/","title":{"rendered":"Treatment Uses Patient&#8217;s Own Immune Cells to Fight Cancer"},"content":{"rendered":"<figure id=\"attachment_2245\" aria-describedby=\"caption-attachment-2245\" style=\"width: 200px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2245\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2015\/12\/red-white-blood-cells.jpg\" alt=\"Treatment Uses Patient's Own Immune Cells to Fight Cancer\" width=\"200\" height=\"259\" \/><figcaption id=\"caption-attachment-2245\" class=\"wp-caption-text\">Treatment Uses Patient&#8217;s Own Immune Cells to Fight Cancer<\/figcaption><\/figure>\n<p>Scientists are hopeful that a new gene therapy <a href=\"http:\/\/issels.com\" target=\"_blank\" rel=\"noopener\">cancer treatment <\/a>will lead to development of other drugs that <a href=\"https:\/\/www.sciencedaily.com\/releases\/2017\/10\/171002202303.htm\" target=\"_blank\" rel=\"noopener\">utilize the power of a patient&#8217;s own immune system<\/a>. In the meantime, policy makers face the challenges of safety, cost and access.<\/p>\n<p><strong>&#8220;Training&#8221; the Immune System to Fight Cancer<\/strong><\/p>\n<p>The therapy in question, called Kymriah, received approval from the Food and Drug Administration (FDA) in August 2017. Novartis developed Kymriah as a cancer treatment for children and young adults with a type of leukemia known as ALL.<\/p>\n<p>Kymriah is a form of <a href=\"https:\/\/issels.com\/blog\/2017\/10\/25\/multiple-myeloma-patients-react-positively-to-car-t-cells-treatment\/\" target=\"_blank\" rel=\"noopener\">chimeric antigen receptor (CAR) T cell treatment<\/a>. A patient&#8217;s T cells are genetically reengineered and infused back into the patient&#8217;s system to attack and kill cancer cells.<\/p>\n<p><strong>Weighing the Pros and Cons<\/strong><\/p>\n<p>During <a href=\"https:\/\/issels.com\/blog\/2017\/11\/17\/cancer-patients-the-struggle-to-understand-clinical-trial-opportunities\/\" target=\"_blank\" rel=\"noopener\">clinical trials<\/a> conducted by Novartis, 63 patients received a one-time infusion of CAR T cells. After three months, 52 of the patients were in remission.<\/p>\n<p>The downside is that 76 percent of the patients experienced a variety of side effects. In order to determine the overall risk vs. reward factor, the FDA has required Novartis to perform a post-marketing study of Kymriah&#8217;s safety and effectiveness.<\/p>\n<p>An article published in the October issue of <em>Health Affairs<\/em> noted that high demand and high cost of CAR T cell therapies could lead to greater inequalities in health outcomes. The authors urged ethics and policy-making to catch up to the science of cancer treatment.<\/p>\n<p><strong>Issels\u00ae: A Pioneer in Cancer Immunotherapy<\/strong><\/p>\n<p>Issels\u00ae has long been ahead of the field in successful use of <a href=\"https:\/\/issels.com\/blog\/2017\/11\/10\/what-makes-the-issels-immunotherapy-approach-so-different\/\" target=\"_blank\" rel=\"noopener\">cancer treatment<\/a> that aids the immune system in targeting tumor cells. <a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\" target=\"_blank\" rel=\"noopener\">Contact us<\/a> for more information.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists are hopeful that a new gene therapy cancer treatment will lead to development of other drugs that utilize the power of a patient&#8217;s own immune system. In the meantime, policy makers face the challenges of safety, cost and access. &#8220;Training&#8221; the Immune System to Fight Cancer The therapy in question, called Kymriah, received approval &hellip; <a href=\"https:\/\/issels.com\/blog\/2018\/01\/17\/treatment-uses-patients-own-immune-cells-to-fight-cancer\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Treatment Uses Patient&#8217;s Own Immune Cells to Fight Cancer<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,580,205,216,538,1],"tags":[539,284,531],"class_list":["post-3094","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-cancer-treatment","category-immuno-oncology","category-immunotherapy","category-immunotherapy-for-cancer","category-uncategorized","tag-cancer-immunotherapy","tag-immune-system","tag-immunotherapy-for-cancer"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3094","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3094"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3094\/revisions"}],"predecessor-version":[{"id":3096,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3094\/revisions\/3096"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3094"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3094"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}