{"id":3184,"date":"2018-03-30T03:52:26","date_gmt":"2018-03-30T08:52:26","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3184"},"modified":"2018-03-06T12:55:21","modified_gmt":"2018-03-06T17:55:21","slug":"research-studies-now-under-way-to-starve-cancer-tumors","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/03\/30\/research-studies-now-under-way-to-starve-cancer-tumors\/","title":{"rendered":"Research Studies Now Under Way to Starve Cancer Tumors"},"content":{"rendered":"
\"Research
Research Studies Now Under Way to Starve Cancer Tumors<\/figcaption><\/figure>\n

According to a popular old wives’ tale, you should starve a cold and feed a fever. Scientists working on immunotherapy for cancer<\/a> are taking that advice a step further as they develop a new treatment that “starves” tumors to death<\/a>.<\/p>\n

Cutting Off Cancer’s Fuel Source<\/strong><\/p>\n

Glutamine is an amino acid found throughout the body, with the largest concentrations in blood and bone. While glutamine plays a major role in cellular synthesis of proteins, it also provides fuel for the rapid cell division of many types of cancer.<\/p>\n

A research team at Vanderbilt University in Nashville began exploring the idea of blocking glutamine from cancer cells as a possible form of treatment. They focused on ASCT2, a protein that transports glutamine to cancer cells as well as other parts of the body.<\/p>\n

The scientists created an ASCT2 inhibitor called V-9302. In testing on both mice and cancer cells developed in vitro, V-9302 was able to stop tumor growth by increasing oxidative stress on cancer cells<\/a>, leaving them to eventually die off.<\/p>\n

Using PET Imaging to Trace Tumors<\/strong><\/p>\n

As the team noted in their report, the next step is to find a way to determine how effective the inhibitors are in restricting glutamine access. The researchers suggested using positron emission tomagraphy (PET) scans<\/a> to spot increases in glutamine metabolic rates.<\/p>\n

Individually Created Immunotherapy for Cancer at Issels\u00ae<\/strong><\/p>\n

Not all cancer patients respond to treatment the same way. That’s why our immunotherapy for cancer<\/a> programs are designed to address each patient’s unique case. Contact us<\/a> to learn more about Issels\u00ae and our track record of helping patients achieve long-term remission.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to a popular old wives’ tale, you should starve a cold and feed a fever. Scientists working on immunotherapy for cancer are taking that advice a step further as they develop a new treatment that “starves” tumors to death. Cutting Off Cancer’s Fuel Source Glutamine is an amino acid found throughout the body, with … Continue reading Research Studies Now Under Way to Starve Cancer Tumors<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,580,2,1],"tags":[212,252,224],"class_list":["post-3184","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-cancer-treatment","category-news","category-uncategorized","tag-cancer-research","tag-cancer-research-advancement","tag-cancer-treatment"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3184"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3184\/revisions"}],"predecessor-version":[{"id":3189,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3184\/revisions\/3189"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3184"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3184"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}