{"id":3193,"date":"2018-03-21T01:16:12","date_gmt":"2018-03-21T06:16:12","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3193"},"modified":"2018-03-12T10:08:20","modified_gmt":"2018-03-12T15:08:20","slug":"personalized-dendritic-cell-vaccines-as-effective-immunotherapy-make-the-news","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/03\/21\/personalized-dendritic-cell-vaccines-as-effective-immunotherapy-make-the-news\/","title":{"rendered":"Personalized Dendritic Cell Vaccines As Effective Immunotherapy Make the News"},"content":{"rendered":"
\"Sharing
Sharing the Opinions of the Future<\/figcaption><\/figure>\n

One of the benefits of immunotherapy for cancer<\/a> is that treatments can often be tailored to address a patient’s individual needs. Scientists in Switzerland have now developed a method of modifying dendritic cell vaccines<\/a> that makes them easier to personalize.<\/p>\n

Aiding the Body’s Own Immune Response<\/strong><\/p>\n

Dendritic cell vaccines<\/a> are normally created by force-feeding dendritic cells with tumor antigens. Scientists at the Swiss Institute for Experimental Cancer Research have developed a modification that allows dendritic cells to acquire antigens from a patient’s tumor.<\/p>\n

Prof. Michele De Palma, winner of the 2017 Swiss Cancer League award, led the team of researchers in creating an extracellular vesicle (EV)-internalizing receptor, referred to as EVIR. The EVIR has been optimized to enhance dendritic cells and their ability to selectively uptake cancer cell-derived EVs.<\/p>\n

Antigen-laden exosomes and other extracellular vesicles are released by tumors in sizable quantities. The EVIR helps dendritic cells target the exosomes more precisely and present them to killer T-cells for a more efficient immune response.<\/p>\n

Streamlining the Job of Dendritic Cells<\/strong><\/p>\n

De Palma explained the phenomenon of cross-dressing, in which dendritic cells<\/a> display the acquired antigens directly on their surface. The process simplifies the immune response by eliminating the need for more complex interactions within the dendritic cell itself.<\/p>\n

Dendritic Cell Vaccines and Immunotherapy for Cancer at Issels\u00ae<\/strong><\/p>\n

Dendritic cell vaccines are only one of the non-toxic cancer treatments available at Issels\u00ae. Our individually developed programs are created to maximize the ability of your own immune system to fight cancer.<\/p>\n

Contact us<\/a> to learn more about why Issels\u00ae has long been a groundbreaking leader in immunotherapy for cancer<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

One of the benefits of immunotherapy for cancer is that treatments can often be tailored to address a patient’s individual needs. Scientists in Switzerland have now developed a method of modifying dendritic cell vaccines that makes them easier to personalize. Aiding the Body’s Own Immune Response Dendritic cell vaccines are normally created by force-feeding dendritic … Continue reading Personalized Dendritic Cell Vaccines As Effective Immunotherapy Make the News<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,538,1],"tags":[528,539,251,269,654],"class_list":["post-3193","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-immunotherapy-for-cancer","category-uncategorized","tag-alternate-cancer-therapy","tag-cancer-immunotherapy","tag-cancer-vaccines","tag-chemo-alternatives","tag-dendritic-cell-vaccine"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3193"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3193\/revisions"}],"predecessor-version":[{"id":3196,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3193\/revisions\/3196"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}