{"id":3212,"date":"2018-04-04T03:11:46","date_gmt":"2018-04-04T08:11:46","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3212"},"modified":"2018-03-27T22:15:42","modified_gmt":"2018-03-28T03:15:42","slug":"liquid-biopsy-test-for-cancer-has-problematic-accuracy-results","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/04\/04\/liquid-biopsy-test-for-cancer-has-problematic-accuracy-results\/","title":{"rendered":"Liquid Biopsy Test for Cancer Has Problematic Accuracy Results"},"content":{"rendered":"
\"Liquid
Liquid Biopsy Test for Cancer Has Problematic Accuracy Results<\/figcaption><\/figure>\n

Early detection improves the chances of successful cancer treatment<\/a>, so recent news of a “liquid biopsy”<\/a> has encouraged the medical community. Unfortunately, the test is showing unacceptable levels of accuracy, leaving the procedure a long way from any real-world applications.<\/p>\n

Controlled vs. Real World Conditions<\/strong><\/p>\n

CancerSEEK<\/a> uses a blood sample for a battery of tests to measure tumor biomarkers and identify cancer-associated DNA mutations. During clinical studies, researchers obtained some promising results.<\/p>\n

By the team’s own admission, the conditions were optimized to facilitate detection of cancer. Even so, most of the cancers detected were late-stage while the goal of screening was to find cancer in the early stages<\/a>.<\/p>\n

Accuracy problems in less-controlled environments became more clear in a 2017 study involving 40 prostate cancer patients who underwent liquid biopsies to fine-tune their therapy programs. Each sample was sent to two different labs with similar technology, but the results differed for more than half of the patients.<\/p>\n

Are Liquid Biopsies the Answer?<\/strong><\/p>\n

Researchers are also questioning the full value of a positive result. While the test may detect the presence of cancer, it gives no clues as to the location of the tumor, unlike traditional screenings<\/a> such as mammograms and CT scans.<\/p>\n

Scientists will no doubt continue to study the science behind liquid biopsies, as detection of circulating tumor DNA can have other applications. The question remains whether liquid biopsies have a viable future as useful cancer screening.<\/p>\n

Personalized Cancer Treatment at Issels\u00ae<\/strong><\/p>\n

We use a variety of specialized non-invasive standard and genomic diagnostic tests to create the cancer treatment<\/a> that’s right for you. Contact us<\/a> for more information.<\/p>\n","protected":false},"excerpt":{"rendered":"

Early detection improves the chances of successful cancer treatment, so recent news of a “liquid biopsy” has encouraged the medical community. Unfortunately, the test is showing unacceptable levels of accuracy, leaving the procedure a long way from any real-world applications. Controlled vs. Real World Conditions CancerSEEK uses a blood sample for a battery of tests … Continue reading Liquid Biopsy Test for Cancer Has Problematic Accuracy Results<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,580,2],"tags":[212,252,500,224,543],"class_list":["post-3212","post","type-post","status-publish","format-standard","hentry","category-cancer-research","category-cancer-treatment","category-news","tag-cancer-research","tag-cancer-research-advancement","tag-cancer-screening","tag-cancer-treatment","tag-liquid-biopsy"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3212","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3212"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3212\/revisions"}],"predecessor-version":[{"id":3223,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3212\/revisions\/3223"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3212"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3212"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}