{"id":3240,"date":"2018-04-23T03:05:28","date_gmt":"2018-04-23T08:05:28","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3240"},"modified":"2018-04-10T21:10:37","modified_gmt":"2018-04-11T02:10:37","slug":"huntingtons-disease-produced-molecules-are-fatal-to-cancer-cells","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/04\/23\/huntingtons-disease-produced-molecules-are-fatal-to-cancer-cells\/","title":{"rendered":"Huntington&#8217;s Disease Produced Molecules Are Fatal to Cancer Cells"},"content":{"rendered":"<figure id=\"attachment_3164\" aria-describedby=\"caption-attachment-3164\" style=\"width: 285px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-3164\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2018\/03\/Depositphotos_7854707_s-285x300.jpg\" alt=\"Huntington's Disease Produced Molecules Are Fatal to Cancer Cells\" width=\"285\" height=\"300\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2018\/03\/Depositphotos_7854707_s-285x300.jpg 285w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2018\/03\/Depositphotos_7854707_s.jpg 689w\" sizes=\"auto, (max-width: 285px) 100vw, 285px\" \/><figcaption id=\"caption-attachment-3164\" class=\"wp-caption-text\">Huntington&#8217;s Disease Produced Molecules Are Fatal to Cancer Cells<\/figcaption><\/figure>\n<p>Could a clue to more effective <a href=\"http:\/\/www.issels.com\" target=\"_blank\" rel=\"noopener\">cancer treatment<\/a> be found in the biochemistry of another illness? Scientists are hopeful that the <a style=\"font-size: 14px;\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/320908.php\" target=\"_blank\" rel=\"noopener\">gene behind Huntington&#8217;s disease<\/a> could be fatal to cancer cells without harming healthy ones.<\/p>\n<p><strong>What Is Huntington&#8217;s Disease?<\/strong><\/p>\n<p>Huntington&#8217;s disease is a genetically inherited condition that destroys nerve cells in the brain. There is currently treatment but no cure for the disorder, which causes a slowly progressive decline in both cognitive and physical abilities.<\/p>\n<p>The faulty gene that triggers Huntington&#8217;s disease contains an excessive number of repeats of a certain sequence of nucleotides, which form the building blocks of <a href=\"https:\/\/issels.com\/blog\/2017\/01\/24\/cancer-may-be-carried-in-your-dna-should-testing-be-offered\/\" target=\"_blank\" rel=\"noopener\">DNA and RNA<\/a>. These sequences create small interfering RNAs, which are molecules that attack specific genes crucial for cell survival.<\/p>\n<p><strong>&#8220;Assassin Molecules&#8221;<\/strong><\/p>\n<p>Brain cells in particular are vulnerable to the cell death caused by small interfering RNAs. <a href=\"https:\/\/issels.com\/blog\/2018\/03\/30\/research-studies-now-under-way-to-starve-cancer-tumors\/\" target=\"_blank\" rel=\"noopener\">Cancer cells<\/a> are also highly susceptible, which is thought to be the reason why Huntington&#8217;s disease patients have such a low incidence of cancer.<\/p>\n<p>A research team at Northwestern University tested these so-called &#8220;assassin molecules&#8221; on human and mouse cancer cells, including brain, breast, colon and ovarian, that were grown in a laboratory. The small interfering RNAs killed all cancer cells from both humans and mice.<\/p>\n<p>Researchers were encouraged that the treatment also showed no toxicity to healthy cells. Further testing is underway to find a more targeted form of delivery.<\/p>\n<p><strong>Targeted Cancer Treatment at Issels\u00ae<\/strong><\/p>\n<p>Our individually developed, non-toxic immunotherapy programs focus on destroying cancer cells and their environment while sparing healthy tissues. <a href=\"http:\/\/66.135.32.155\/issels\/Questionnaire\/request-issels-info.aspx\" target=\"_blank\" rel=\"noopener\">Contact us<\/a> for more information about <a href=\"https:\/\/issels.com\/blog\/2018\/03\/28\/swiss-group-studies-dendritic-cell-vaccines-with-artificial-receptors\/\" target=\"_blank\" rel=\"noopener\">cancer vaccines<\/a> and other targeted cancer treatment protocols at Issels\u00ae.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Could a clue to more effective cancer treatment be found in the biochemistry of another illness? Scientists are hopeful that the gene behind Huntington&#8217;s disease could be fatal to cancer cells without harming healthy ones. What Is Huntington&#8217;s Disease? Huntington&#8217;s disease is a genetically inherited condition that destroys nerve cells in the brain. There is &hellip; <a href=\"https:\/\/issels.com\/blog\/2018\/04\/23\/huntingtons-disease-produced-molecules-are-fatal-to-cancer-cells\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Huntington&#8217;s Disease Produced Molecules Are Fatal to Cancer Cells<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,580,537,205,216,538,2,1],"tags":[222,539,252,676,578,442],"class_list":["post-3240","post","type-post","status-publish","format-standard","hentry","category-cancer-research","category-cancer-treatment","category-cancer-vaccine","category-immuno-oncology","category-immunotherapy","category-immunotherapy-for-cancer","category-news","category-uncategorized","tag-advanced-cancer-research","tag-cancer-immunotherapy","tag-cancer-research-advancement","tag-cancer-vaccine","tag-future-cancer-research","tag-new-cancer-research-methods"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3240"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3240\/revisions"}],"predecessor-version":[{"id":3248,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3240\/revisions\/3248"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3240"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}