{"id":3411,"date":"2018-08-17T01:18:10","date_gmt":"2018-08-17T06:18:10","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3411"},"modified":"2018-08-08T14:04:21","modified_gmt":"2018-08-08T19:04:21","slug":"genetic-testing-identifies-best-immunotherapy-prospects-for-prostate-cancer-patients","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2018\/08\/17\/genetic-testing-identifies-best-immunotherapy-prospects-for-prostate-cancer-patients\/","title":{"rendered":"Genetic Testing Identifies Best Immunotherapy Prospects for Prostate Cancer Patients"},"content":{"rendered":"
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New Treatments for Prostate Cancer<\/figcaption><\/figure>\n

While immunotherapy has proven to be a viable form of cancer treatment<\/a>, not all patients respond to the currently available methods. A major breakthrough occurred this summer, when scientists found that genetic testing could identify prostate cancer patients who are likely candidates for immunotherapy<\/a>.<\/p>\n

Treating Prostate Cancer with Immunotherapy<\/strong><\/p>\n

Last June, a major clinical trial provided the first evidence that advanced prostate cancer could be successfully treated with an immunotherapy drug called pembrolizumab<\/a>. Approximately ten percent of patients responded, so the question became how to determine which patients to treat.<\/p>\n

A possible answer came in the form of a study recently published in Cell<\/em>. Scientists from London’s Institute of Cancer Research and the University of Michigan joined forces to analyze tumor DNA collected from 360 men with advanced prostate cancer in various countries.<\/p>\n

Is Genetic Testing the Solution?<\/strong><\/p>\n

Results indicated that seven percent of the tumors lacked a gene called CDK12. This feature is a hallmark of a unique genetic pattern that contains a greater amount of immune cells than other types of advanced prostate cancer.<\/p>\n

In addition, these tumors had more neoantigens, which are proteins that alert the immune system to the presence of cancer cells. Thanks to the higher numbers of immune cells and neoantigens<\/a>, the immune system already begins to recognize the tumor, which is why scientists think such tumors are more receptive to immunotherapy.<\/p>\n

Cancer Treatment for Therapy-Resistant Tumors<\/strong><\/p>\n

Issels\u00ae uses genetic testing<\/a> to individually develop cancer treatment programs that are best suited to a patient’s specific needs. Visit our website<\/a> to learn how we have been successfully using integrative immunotherapy methods to treat advanced cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"

While immunotherapy has proven to be a viable form of cancer treatment, not all patients respond to the currently available methods. A major breakthrough occurred this summer, when scientists found that genetic testing could identify prostate cancer patients who are likely candidates for immunotherapy. Treating Prostate Cancer with Immunotherapy Last June, a major clinical trial … Continue reading Genetic Testing Identifies Best Immunotherapy Prospects for Prostate Cancer Patients<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203,580,538],"tags":[509,219,531],"class_list":["post-3411","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","category-cancer-treatment","category-immunotherapy-for-cancer","tag-immuno-oncology","tag-immunotherapy","tag-immunotherapy-for-cancer"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3411","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3411"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3411\/revisions"}],"predecessor-version":[{"id":3416,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3411\/revisions\/3416"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}