{"id":3519,"date":"2022-11-30T11:15:28","date_gmt":"2022-11-30T16:15:28","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3519"},"modified":"2022-12-12T15:05:54","modified_gmt":"2022-12-12T20:05:54","slug":"low-protein-diets-may-lower-the-risk-of-cancer","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2022\/11\/30\/low-protein-diets-may-lower-the-risk-of-cancer\/","title":{"rendered":"Low Protein Diets May Lower the Risk of Cancer"},"content":{"rendered":"

In recent years,\u00a0Keto, Paleo and other high-protein diets have been grabbing all the headlines. Despite their popularity for weight loss, a low-protein diet<\/a> may be more valuable in preventing tumors, according to cancer immunotherapy<\/a> studies.<\/p>\n

Protein and the Immune System<\/strong><\/p>\n

Yes-associated protein, referred to as YAP, is found in the population of\u00a0T-cells, which are the warriors of the immune system. A team of scientists conducted research to explore the effects of YAP in the immune system’s response to cancer.<\/p>\n

Studies were done using a group of mice that were genetically engineered to have low YAP in many of the T-cell populations. In particular, research focused on the relationship between YAP and Tregs, a regulatory T-cell that’s instrumental in preventing autoimmune diseases but interferes with cancer immunotherapy<\/a>.<\/p>\n

Results indicated that YAP activity suppresses T-cell function. When YAP levels are reduced or eliminated, it serves to stimulate T-cell function, allowing them to infiltrate solid tumors and block additional tumor growth.<\/p>\n

Since Tregs\u00a0inhibit the effects of immunotherapy, targeting YAP activity<\/a> toward Tregs can be a positive use. The study, which was published in Journal of Cancer Discovery<\/em>, offers promising implications for new methods to improve patient responses to immunotherapy.<\/p>\n

Potential Benefits of Low-Protein Diets<\/strong><\/p>\n

In addition to possible applications in cancer treatment, low-protein diets have been used to improve other health conditions.<\/p>\n