{"id":3543,"date":"2022-12-21T11:15:54","date_gmt":"2022-12-21T16:15:54","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=3543"},"modified":"2022-12-28T14:57:24","modified_gmt":"2022-12-28T19:57:24","slug":"fevers-boost-the-immune-response-new-study-focuses-on-the-cancer-connection","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2022\/12\/21\/fevers-boost-the-immune-response-new-study-focuses-on-the-cancer-connection\/","title":{"rendered":"Fevers Boost the Immune Response &#8211; New Study Focuses on the Cancer Connection"},"content":{"rendered":"<p>Most people just want to crawl back into bed when they&#8217;re running a fever. Who would have thought there may be a positive aspect to feeling so bad?\u00a0Incredibly, <a href=\"https:\/\/www.aninews.in\/news\/health\/research-explores-relationship-between-fever-and-cancer-occurrence201808191014380001\/\" target=\"_blank\" rel=\"noopener\">a published\u00a0study<\/a> indicates there may be a connection between fever\u00a0and <a href=\"https:\/\/issels.com\" target=\"_blank\" rel=\"noopener\">cancer immunotherapy<\/a>.<\/p>\n<p><strong>What Is a Fever?<\/strong><\/p>\n<p>Infectious fever is one of the\u00a0immune system responses to foreign organisms. When bacteria known as exogenous pyrogens enter the body, it triggers the immune system to produce endogenous pyrogens, or mediators, to fight them. This begins a chain of events that culminates in a rising temperature.<\/p>\n<p>Endogenous mediators include <a href=\"https:\/\/issels.com\/blog\/2013\/09\/06\/cytokines-fighting-cancer-at-the-cellular-level\/\" target=\"_blank\" rel=\"noopener\">cytokines<\/a>,\u00a0such as interleukins and interferons. During a fever, these mediators redirect metabolic substrates and energy, resulting in a higher range of immune effectors. One such effector is lymphocytes that express gd T cells.<\/p>\n<p><strong>How a Fever Affects the Immune System<\/strong><\/p>\n<p>A fever generates large numbers of gamma delta <a href=\"https:\/\/issels.com\/blog\/2017\/02\/09\/strategic-t-cells-use-may-be-the-key-to-effective-cancer-treatment\/\" target=\"_blank\" rel=\"noopener\">T cells<\/a>. These cells are valuable in fighting infection that initiates the fever response. They also have potent anti-tumor properties, which may have applications for cancer immunotherapy methods. This process indicates that a high incidence of fevers may actually reduce the risk of cancer.<\/p>\n<p>Past research has largely involved alpha beta T cells. While the connection between the fever response and cancer is still largely anecdotal, researchers now have a foundation to expand studies on the topic along with\u00a0possible clinical benefits. This specific study, based on patient accounts documented over several decades,\u00a0was first published in <em>Quarterly Review of Biology<\/em>.<\/p>\n<p><strong>Cancer Immunotherapy: The Issels\u00ae Difference<\/strong><\/p>\n<p>Our <a href=\"https:\/\/issels.com\/treatment-summary\/index.html\" target=\"_blank\" rel=\"noopener\">personally tailored\u00a0immunotherapy programs<\/a> are designed to help the body&#8217;s own immune system fight tumors. These non-toxic vaccines and cell therapies avoid the adverse side effects that accompany many traditional cancer treatments.\u00a0<a href=\"https:\/\/issels.com\/issels-immunotherapy-difference.html\" target=\"_blank\" rel=\"noopener\">Visit our website<\/a> to learn more about the Issels\u00ae Difference.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Most people just want to crawl back into bed when they&#8217;re running a fever. Who would have thought there may be a positive aspect to feeling so bad?\u00a0Incredibly, a published\u00a0study indicates there may be a connection between fever\u00a0and cancer immunotherapy. What Is a Fever? Infectious fever is one of the\u00a0immune system responses to foreign organisms. &hellip; <a href=\"https:\/\/issels.com\/blog\/2022\/12\/21\/fevers-boost-the-immune-response-new-study-focuses-on-the-cancer-connection\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Fevers Boost the Immune Response &#8211; New Study Focuses on the Cancer Connection<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":3548,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[580,1],"tags":[539,212,224],"class_list":["post-3543","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer-treatment","category-uncategorized","tag-cancer-immunotherapy","tag-cancer-research","tag-cancer-treatment"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3543","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=3543"}],"version-history":[{"count":2,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3543\/revisions"}],"predecessor-version":[{"id":3549,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/3543\/revisions\/3549"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media\/3548"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=3543"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=3543"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=3543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}