{"id":857,"date":"2013-11-04T05:00:24","date_gmt":"2013-11-04T10:00:24","guid":{"rendered":"https:\/\/issels.com\/blog\/?p=857"},"modified":"2015-02-09T16:05:11","modified_gmt":"2015-02-09T21:05:11","slug":"cold-sore-virus-could-hold-key-to-new-cancer-treatments","status":"publish","type":"post","link":"https:\/\/issels.com\/blog\/2013\/11\/04\/cold-sore-virus-could-hold-key-to-new-cancer-treatments\/","title":{"rendered":"Cold Sore Virus Could Hold Key to New Cancer Treatments"},"content":{"rendered":"<figure id=\"attachment_675\" aria-describedby=\"caption-attachment-675\" style=\"width: 200px\" class=\"wp-caption alignright\"><a href=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/08\/MP9003901121.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-675\" src=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/08\/MP9003901121-200x142.jpg\" alt=\"Cold Sores Are a Cure For Cancer?\" width=\"200\" height=\"142\" srcset=\"https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/08\/MP9003901121-200x142.jpg 200w, https:\/\/issels.com\/blog\/wp-content\/uploads\/2013\/08\/MP9003901121.jpg 600w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><figcaption id=\"caption-attachment-675\" class=\"wp-caption-text\">Can the Cold Sore Virus be\u00a0a Cure For Cancer?<\/figcaption><\/figure>\n<p>\u201cWe\u2019re trying to give cancer a cold sore,\u201d is how <a href=\"http:\/\/www.livescience.com\/40353-the-cold-sore-virus-may-help-kids-fight-cancer.html\" target=\"_blank\">Dr. Timothy Cripe<\/a>, a pediatric oncologist at Nationwide Children\u2019s Hospital in Columbus, Ohio, explains his team\u2019s research on viral therapy. Viral therapy uses altered forms of common viruses, such as the herpes simplex virus that causes cold sores, to fight cancer. When injected into cancer tumors, viruses trigger the body\u2019s immune system response and serve as bull\u2019s eyes, allowing immune system cells to find and attack the tumors. To date, most viral therapy has focused on adult cancers. Dr. Cripe and his colleagues are among the first to research its potential to fight childhood cancers.<\/p>\n<p>Earlier this year, research findings presented at the annual meeting of the <a href=\"http:\/\/abcnews.go.com\/Health\/Healthday\/story?id=4507864\" target=\"_blank\">European Society for Medical Oncology<\/a> in Switzerland showed promising results using modified herpes simplex virus to target liver and colorectal cancer cells. Scientists were successful in creating a genetically modified herpes virus that killed cancer cells without harming healthy tissue. One of the biggest problems with the most prevalent traditional cancer treatments &#8212; chemotherapy and radiation \u2013 is that they cast too wide a toxic net, killing both healthy and cancerous cells which can cause patients to suffer traumatic side effects.<\/p>\n<p>Herpes simplex virus \u201cdoesn\u2019t replicate in normal, healthy cells, so our hope is that it will help fight cancers without causing side effects in the rest of the body\u201d Dr. Axel Mescheder of German biotech company MediGene said in a statement issued at the conference.<\/p>\n<p>Viral therapy has the potential to join other successful, non-toxic cancer treatments such as <a href=\"http:\/\/www.issels.com\/advancedtargetedtherapies.aspx#sthash.Vt7Ser4E.ejaYpYsR.dpbs\" target=\"_blank\">targeted cell therapie<\/a>s and <a href=\"http:\/\/www.issels.com\/Vaccines.aspx#sthash.AdmmMmJ7.fBmTvJRM.dpbs\" target=\"_blank\">cancer vaccines<\/a> in expanding the treatment horizons of immunotherapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cWe\u2019re trying to give cancer a cold sore,\u201d is how Dr. Timothy Cripe, a pediatric oncologist at Nationwide Children\u2019s Hospital in Columbus, Ohio, explains his team\u2019s research on viral therapy. Viral therapy uses altered forms of common viruses, such as the herpes simplex virus that causes cold sores, to fight cancer. When injected into cancer &hellip; <a href=\"https:\/\/issels.com\/blog\/2013\/11\/04\/cold-sore-virus-could-hold-key-to-new-cancer-treatments\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Cold Sore Virus Could Hold Key to New Cancer Treatments<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,203],"tags":[215,339],"class_list":["post-857","post","type-post","status-publish","format-standard","hentry","category-alternative-cancer-treatment","category-cancer-research","tag-cancer-care","tag-cold-sores"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/857","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/comments?post=857"}],"version-history":[{"count":4,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/857\/revisions"}],"predecessor-version":[{"id":1642,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/posts\/857\/revisions\/1642"}],"wp:attachment":[{"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/media?parent=857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/categories?post=857"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/issels.com\/blog\/wp-json\/wp\/v2\/tags?post=857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}