Issels Integrative Immuno-Oncology August 30, 2018  

New Research: UroSEEK Test Looks for Gene Mutations Causing Bladder Cancer

Dear Friend,

What if you could determine your need for bladder cancer treatment from a routine urine sample, just like many other medical conditions? Scientists have recently developed a test that could make this a reality.

Using Gene-Based Testing for Early Cancer Detection

A team of researchers at Johns Hopkins Kimmel Cancer Center has been studying cancer genes to find more effective methods of early detection. Earlier this year, they announced a new blood test called CancerSEEK, which screens for eight different types of cancer, and PapSEEK, which screens for endometrial and ovarian cancers via cervical fluid samples.

In a study published in March, the team revealed the addition of another test called UroSEEK. Urine samples are analyzed for the presence of gene mutations or abnormal numbers of chromosomes, both of which are associated with bladder cancer and upper tract urothelial cancer (UTUC).

Identifying New Cancer Cases and Recurrences

During clinical studies involving 570 at-risk patients, UroSEEK had an 83 percent success rate identifying those who did develop bladder cancer. When UroSEEK was used in conjunction with cytology, the standard test for bladder cancer, accuracy rose to 95 percent.

According to Dr. David McConkey of the Johns Hopkins Greenburg Bladder Cancer Institute, bladder cancer has a high rate of recurrence. Another benefit of UroSEEK is that it can be used to effectively monitor patients who have already undergone treatment for bladder cancer.

Individualized Cancer Treatment for Each Patient

At Issels®, we have been using FDA-approved gene-targeted therapies as one of the components of our integrative cancer treatment programs. Contact us for more information about our non-toxic protocols.

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New Research: UroSEEK Test Looks for Gene Mutations Causing Bladder Cancer

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New Breast Cancer Treatments May Be Studied After Gene Research

After discovering a bounty of genes linked to breast cancer, scientists may soon be able to develop new genetic tests for predicting breast cancer risk, and using the data obtained, ensure targeted cancer treatment for patients.

Thirty-two additional genes, linked to survival in those with receptor-positive breast cancer, were also uncovered. These are hoped to be used to test new treatments, as well as for providing targeted prevention protocols for those most at-risk of developing breast cancer.

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Will CRISPR Gene Editing Play A New Role In Cancer Treatment?

All biological life forms are composed of three primary substances. DNA, the building block of genes, uses RNA as a messenger to control proteins, which are the cellular "worker bees." RNA and proteins can be targeted with drugs, medicines and other treatments, but DNA is more complicated.

CRISPR is a process that lets scientists actually manipulate and make changes to genetic material in cells. In theory, CRISPR could be used to "edit" diseases such as cancer right out of patients.

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Videos – What Do Patients Say About Their Experience?

Watch videos of patients who share their own experiences at the Issels clinics with you. Listen to their stories and cancer journeys.

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