Category Archives: Cancer Research

FDA Quickly Approves New One-of-a-Kind Cancer Treatment

There is New Hope for Cancer Patients.
There is New Hope for Cancer Patients.

Researchers have made a number of significant breakthroughs in cancer treatment, but a recent development has the healthcare community particularly excited. The Food and Drug Administration (FDA) has approved a drug that treats tumors based on a genetic abnormality.

Keytruda: A Landmark in Immunotherapy for Cancer

Pembrolizumab, marketed under the trade name Keytruda, was tested on a trial group of 86 patients. The results were remarkable: 66 patients saw their tumors shrink and stabilize, while the tumors in 18 of them disappeared with no recurrence.

What’s different about Keytruda? It’s the first drug that attacks tumors from a shared genetic profile rather than the actual location of the tumor. A prospective patient first undergoes testing to determine whether he or she is a genetic match for the mutations targeted by Keytruda.

Current and Future Possibilities

At present, Keytruda is approved for treating only select forms of advanced bladder, lung and melanoma tumors. The drug will be effective for approximately four percent of cancer patients, which still equates to tens of thousands of people.

Scientists are encouraged by the possibility of further treatment methods tailored to a patient’s specific genetic profile. This ability would greatly enhance development of more accurate targeting and treatment.

Advanced Immunotherapy for Cancer Treatment from Issels®

Issels® uses genomic testing to determine a patient’s individual treatment needs. We then use the information to tailor a personalized immunotherapy for cancer program including methods such as vaccines and NK cells.

We have helped patients with all forms of cancer achieve long-term remission. Contact us to learn more about why the Issels® difference may be right for you.

UV Exposure and the Skin Cancer Connection

Sun Exposure and Cancer
Sun Exposure and Cancer

Exposure to ultra-violet (UV) rays can have more serious consequences than a painful sunburn. UV rays from both natural and man-made sources can increase risk of developing skin cancer.

How UV Rays Damage Skin

While UV rays come primarily from the sun, they contain more energy than visible light. Man-made sources of UV rays include tanning beds and welding torches.

UV rays are powerful enough to ionize atoms by removing an electron, which is how they cause damage to DNA in body cells. But they don’t have enough energy to penetrate to organs and other internal tissues, which is why their effect is seen mostly on skin.

UV Ray Wavelengths

The three types of UV rays are:

  • UVA rays, which are the weakest of the three and linked more to cosmetic damage such as wrinkles than to skin cancer.
  • UVB rays, which are slightly stronger and the main cause of sunburns and skin cancer.
  • UVC rays, which have the most energy but are prevented from reaching the ground by the ozone layer.

Preventing UV Ray Exposure

A certain amount of sunshine is necessary for good health, but protect yourself by applying sunscreen to exposed parts of your body when you’re outside for extended periods. Avoid peak hours of 11 AM until 4 PM and stay in the shade when possible.

Immunotherapy for Cancer: Restoring the Body’s Natural Defenses

At Issels®, our integrative immunotherapy treatments boost your own immune system’s ability to fight cancer. Contact us for more information to learn how immunotherapy for cancer has helped patients diagnosed with skin cancer, melanoma and other types of tumors.

Coaches vs. Cancer Has Raised $100 Million for Cancer Research

Coaches and Teams Have Raised Millions for Research
Coaches and Teams Have Raised Millions for Research

Actors, athletes and other high-profile people often use their celebrity to help promote awareness of cancer research. One such program is Coaches vs. Cancer, which has raised more than $100 million to support the American Cancer Society (ACS).

Leading the Charge Against Cancer

As with most Americans, basketball coaches across the country have been affected by cancer, either personally or through a loved one. The National Association of Basketball Coaches (NABC) has partnered with the ACS to form Coaches vs. Cancer, a program designed to empower the coaches to participate in the fight against cancer.

Coaches vs. Cancer: The “Battles”

Thanks to their personal and professional experiences and positions of leadership, basketball coaches are in a great position to raise awareness of cancer research among their teams and communities. Some of their creative initiatives have included:

  • In February 2017, their 3-Point Challenge let fans pledge an amount for every successful three-point shot made by their favorite team that month.
  • During Suits and Sneakers Week, coaches across the country wear sneakers on game day to symbolize the role of nutrition and physical activity in reducing cancer risk.
  • Hardwood Heroes is part of March Madness, the NCAA’s popular basketball championship tournament. 2017 marked the second year of this event in which a basketball team made up of cancer survivors took on a team of survivors from last year’s game.

Issels®: The Leader in Immunotherapy for Cancer Treatment

For decades, Issels® has raised the bar on cancer treatment with our non-toxic and integrative immunotherapy programs. Visit our website to read and hear testimonials from patients who have achieved long-term remission.

Where Your Body Stores Fat May Predict Where You May Get Cancer

Where You Store Fat is Important
Where You Store Fat is Important

Excess weight has long been recognized as a risk factor for developing cancer. According to a recent study published in the British Journal of Cancer, where body fat is carried can be another indicator of obesity-related cancer risk.

Body Shape Can Increase Cancer Risk

The study, conducted by scientists at the International Agency for Research on Cancer (IARC) of the World Health Organization, were the first to compare adult body measurements in a standardized way. Data was obtained from 43,000 participants, 1,600 of whom had been diagnosed with an obesity-related cancer, and who were observed over an average of 12 years.

Results showed that an additional four inches added to the waistline equated to a 13 percent increase in the risk for obesity-related cancers. More significantly, adding three inches to the hips can boost the risk of bowel cancer by 15 percent.

How Can Obesity Cause Cancer?

Obesity is the second largest preventable cause of cancer behind smoking. Excess body fat alters the level of sex hormones, triggering an increase in production of insulin, ultimately leading to inflammation. All three factors have been linked to an increased risk of cancer.

Dr. Heinz Freisling, lead author of the study, explains that further investigation is needed to explore the connection between cancer and fat carried around the midsection, but results indicate that body shape should be considered along with body mass index (BMI) when evaluating cancer risk.

Non-Toxic, Integrative Cancer Treatment for All Ages at Issels®

Our individually developed cancer treatment programs have been successful with people of all ages and all forms of cancer. Contact us for more information.

Cancer Research Embraces the Age of Super Computing

Supercomputers Catapult Speed of Research Ahead.
Supercomputers Catapult Speed of Research Ahead.

Can technology be the key that unlocks the secret to curing cancer? A report from the Cancer Moonshot Task Force confirmed the importance of supercomputers to research focusing on immunotherapy for cancer and other effective treatments.

HPC: A High-Tech Weapon Against Cancer

The Cancer Moonshot program originated in 2016 with the support of then-Vice President Joe Biden. At the time, Energy Secretary Ernie Monitz, a member of the task force, wrote about the role of high performance computing (HPC) in analyzing complex databases to identify patterns and other vital information.

How Cancer Researchers Use HPC

HPC systems such as the one at the Texas Advanced Computing Center use seven basic methodologies to understand cancer biology and possible treatments.

• Molecular simulations of protein and drug interactions help to create more effective treatments.

• Bioinformatics unravel the complexities of cancer genomes.

• Mathematical modeling is used to develop formulas that predict how cancer will behave.

• Quantum calculations help to refine radiation therapies.

• Computational treatment planning creates the pinpoint accuracy required to prevent radiation from damaging organs and healthy tissues.

• Computational trial design is used in immunotherapy for cancer to gauge the correct combination of dosages.

• Machine learning is how researchers develop algorithms and other statistical methods to analyze and interpret massive datasets.

Cancer Treatment Is Not “One Size Fits All”

Issels® uses state-of-the-art testing methods to design a personalized immunotherapy for cancer treatment that addresses a patient’s specialized needs. Contact us to learn more about cancer vaccines, NK cells, hyperthermia and other non-toxic treatment programs at Issels®.

One in five US Cancer Patients Are Diagnosed with a Rare Cancer

1 in 5 US Cancer Patients Are Diagnosed with a Rare Cancer
1 in 5 US Cancer Patients Are Diagnosed with a Rare Cancer

Rare cancers are more common than you think. As a group, they make up about 20% of all cancer diagnoses. However, each specific type of rare cancer is still very dangerous because the symptoms are often misdiagnosed. At Issels®, we often see patients whose rare cancer went undiagnosed despite several rounds of doctor visits and tests.

The American Cancer Society recently shed light on the frequency of rare cancer diagnoses:

  • Rare cancer is defined by annual diagnoses in less than 6 out of 100,000 people
  • 71% of all cases in people under 20 years old are rare types
  • 39% of all cases in people 20 to 39 years old are rare types
  • Younger people have better survival rates for rare cancer than older people

Together, Learning More About Rare Cancers

In some cases, standard cancer treatment fails to work as well as it does for common types of cancer. On the other hand, the ACS notes that innovations in rare cancer treatment often help scientists develop better treatment for all types of cancers.

After a rare cancer diagnosis, it can be difficult to find information if your physicians are not very familiar with the disease. We specialize in advanced stage cancer treatment at Issels®, including rare types of the disease that are not responding well enough to standard therapies.

At Issels®, we offer individualized treatments including cancer vaccines developed using the patient’s own autoimmune cells. Such treatments, known as immunotherapy, are helping patients with standard therapy–resistant and advanced stages of cancer.

Learn more about our integrative immunotherapy approach to cancer treatment on our website or contact us for more info.