In TheJournal.ie, an Irish news website, a woman named Liz Burke shared her experiences in honor of Daffodil Day, a fundraiser for the Irish Cancer Society. Liz was originally diagnosed with breast cancer in 2007.
After a lumpectomy, Liz underwent a course of chemotherapy followed by another of radiotherapy. She demonstrated her sense of humor by relating a story about purchasing a wig to cover her baldness and finding it one day in the mouth of her Jack Russell terrier.
Two years later, Liz’s doctor discovered that breast cancer cells had metastasized to her liver. This triggered another nine months of chemotherapy followed by two years of maintenance, but the good news is that the tumors became inactive.
Finally, one more blow. After five years, the breast cancer metastasized again, this time resulting in a brain tumor. Liz had surgery to remove the tumor and radiotherapy treatment afterwards.
“People Survive Cancer”
These days Liz follows a regular schedule of MRIs, CT scans and weekly infusions. Her message? “People can live quite happily alongside cancer.” Liz believes we’re lucky to live in a time when so much progress is being made with new and effective cancer treatment.
Issels®: There IS Life After Cancer
Many of our patients at Issels® have similar stories of hope and recovery. Visit our website to read and hear their testimonials.
Lung cancer is one of the most common types of cancers in the U.S., as well as a top cause of preventable cancer death. Although anyone can develop this type of cancer, certain individuals have a higher risk. Those who smoke or have nicotine dependence face a considerably increased risk of having lung cancer.
With more research focusing on improving outcomes for lung cancer through cancer immunotherapy and other treatment methods, scientists need to learn more about the causes of this disease. A research team at Dartmouth’s Geisel School of Medicine studied potential pathways that lead to lung cancer.
Nicotine Dependence as a Pathway
Researchers studied possible pathways that allow a chromosome called 15q25.1 to raise an individual’s risk of lung cancer. This chromosome has previously been identified as a genetic component that can increase lung cancer risks in some individuals. The research team found two pathways associated with this chromosome that could help explain how it leads to a higher lung cancer risk.
Nicotine dependence is linked to the first pathway that the researchers found. This finding has helped scientists better understand how lung cancer develops and why individuals with a history of smoking and certain genetic components face a significantly higher risk of having lung cancer. The second pathway is linked to biological processes, including those involving the immune system.
Improved Lung Cancer Treatments
The findings of this research could pave the way for improved treatments for lung cancer. Scientists can use these findings to come up with ways to block risky genetic variants, resulting in better outcomes for those with cancer. The results of this study might also be used to develop more effective ways to treat lung cancer using the body’s immune system or other methods.
For more information on cancer treatment and cancer immunotherapy, please contact Issels® today.
A study by Dr. Rowan Chlebowski, a medical oncologist at Harbor-UCLA Medical Center’s Los Angeles Biomedical Research Institute, shows that some women diagnosed with breast cancer who maintain a low-fat diet may reduce their risk of early death.
Research for women in the early stages of breast cancer specific to estrogen receptor-negative (ER-negative) cancer showed positive results. For this group, Dr. Chlebowski’s study showed a reduced risk of death factor of 36 percent over a 15-year study for patients who maintained a diet of low-fat food for five years after being diagnosed.
For women diagnosed with both ER-negative and progesterone-receptor negative (PR-negative) cancer, the results were even higher. Following the same five year low-fat diet regimen after initial diagnosis, patients experienced a 56 percent reduction in risk of death due to any cause.
The study included over 2,400 women ranging in age from 48 to 79 in the early stages of breast cancer. Of the 2,400 women, approximately 1,600 were diagnosed with ER-positive cancer while the remaining 800 were diagnosed with ER-negative or both ER and PR-negative cancer.
During the study, low-fat diets for half of the women was a requirement. Unannounced checks were made throughout the study. The other group was not required to maintain a low-fat diet. The study showed a lower death rate in the low-fat diet research group.
The study is the first where a low-fat diet over an extended period for cancer patients has been researched.
For information about how the Issels integrative immuno-oncology works in the treatment of breast cancer, contact Issels®. Established in 1951, Issels® has made a name for itself internationally for its success in the long-term remission of advanced tumors.
People are always looking for the next great diet in an effort to lose weight. The recently popular ketogenic diet could have some surprising benefits for patients undergoing cancer treatment.
The Warburg Effect
Cancer cells proliferate via the Warburg effect, named for the scientist who first advanced the idea. Fermentation is a process by which sugars are metabolized to provide energy for bacteria. Sauerkraut and yogurt are some of the more widely-known products of fermentation.
Unlike normal body cells, which derive their energy from mitochondria, cancer cells receive energy from fermentation of glucose within cytoplasm. When a cell starts getting energy from glucose, it can be the first sign of abnormal cell function that ultimately results in formation of a tumor.
The Ketogenic Diet: Starving Cancer Cells
A keto diet plan is low in carbohydrates and high in fat. The science behind it is based on a biological response that dates back to prehistoric times. When food was scarce, the body responded by shifting metabolic gears and using stored fat as fuel.
When the body’s supply of carbs is restricted, it shuts off the flow of glucose and other cancer-promoting fuels. As cancer cells become compromised, the body resumes its normal cellular signaling, putting the brakes on further tumor development.
The keto diet should not be considered a cure for cancer. However, it’s a valuable tool for use in conjunction with immunotherapy and other cancer treatment.
Immunotherapy and Nutrition: A Winning Combination
Good nutrition is a perfect complement for our non-toxic cancer treatment programs. Visit our website for more information about cancer vaccines and other individually created treatments.
Cancer is effected by numerous and complex risk factors, making concepts related to calculating its risk a frequent subject of debate. Adding to this debate is a recent study looking at randomly mutating cells, specifically how they play a predominant role in cancer development. What does this say about your cancer risk? Issels® wants to help you put this new information in perspective.
Cancer and car accidents: They have a lot in common…
Comparing getting cancer to getting into a car accident, the length of your trip – your lifespan – increases your risk. The longer you live, the more the odds increase of your body randomly mutating cells, making this a significant risk factor – attributable to two-thirds of your total cancer risk in fact.
Just as rain or snow can increase your risk of an accident, so too can conditions in your body and in your environment increase your risk of cancer.
Bad brakes or worn tires can be seen as a metaphor for genetic factors, such as inherited mutations.
Reading the accident report
Despite this research, it can’t be stressed enough no single factor causes cancer. Two-thirds of car accidents are not related solely to trip length, but to a combination of road conditions, mechanical issues, and the like. For each “accident,” the major contributing factor will vary.
Due to the large combination of risk factors, there are many opportunities for prevention, including addressing radiator issues (smoking), regular maintenance (early diagnostics and detection), and more.
Cancer spinning out of control? Contact Issels® today.
The study, conducted by a multi-disciplinary team from the University of Adelaide, involved a protein called proliferating cell nuclear antigen (PCNA). PCNA’s donut-like shape lets DNA slide through its center, where it is then replicated.
As explained by project leader Dr. John Bruning, while PCNA is required for DNA replication, it’s overexpressed in 90 percent of all cancers. The team set out to find a way to target PCNA, thereby preventing cancer cells from multiplying.
Creating a Barrier to Cancer Cell Proliferation
Bruning’s team successfully created a drug-like molecule using a protein that naturally interacts with PCNA. They were also able to change the chemistry to keep it from degrading as it does in its natural form.
PCNA rarely mutates, making it less likely to develop resistance against the “designer molecule,” which has demonstrated greater effectiveness than previous forms of PCNA inhibitors with less chance of side effects.
According to Bruning, the use of a natural protein in the creation of the molecule allows for more precise targeting of PCNA. Bruning is hopeful that his team’s work will usher in the development of a whole new class of drugs.
Immunotherapy for Cancer at Issels®: Using the Body’s Own Resources