Category Archives: Cancer Treatment

Cancer Research, Cancer Treatment, Immunotherapy for Cancer, Living with Cancer

In the News: Low Dose Aspirin Reduces Cancer Death Risk

May 2, 2017 Chris 2 Comments

Low Dose Aspirin Therapy May Reduce Cancer Death Risk

Could aspirin become a powerful weapon in immunotherapy for cancer? Researchers have found evidence that a daily regimen of low-dose aspirin may lower the mortality rate of cancer patients.

An Aspirin a Day

Aspirin is an anti-inflammatory drug that has been used as a pain reliever since the days of ancient Egyptians. In early April, attendees at the American Association for Cancer Research meeting in Washington, D.C. learned why aspirin also holds promise for treating cancer patients.

Yin Cao, an instructor at Massachusetts General Hospital and Harvard Medical School, reviewed data from long-term health studies involving both men and women. While the overall risk of death was lower for individuals who took a daily dose of aspirin, Cao found that the risk of dying from cancer was 7 percent lower in women and 15 percent lower in men.

The connection was most dramatic with colorectal cancer, as women had a 31 percent lower risk and men’s risk was 30 percent lower. Significant reductions were also found among women with breast cancer and men with prostate or lung cancer.

Is Aspirin Treatment for Everyone?

Despite the encouraging results, Cao offered a note of caution for anyone considering this course of medication. Aspirin increases risk of ulcers and gastrointestinal bleeding, so Cao emphasized the importance of consulting with your doctor before undertaking a daily program.

Issels®: Fighting Cancer and Its Causes

Our immunotherapy for cancer treatment programs go beyond eliminating tumors to helping your immune system regain its natural defense mechanisms. Contact us to learn more about cancer vaccines and our other personally tailored integrative programs.

Cancer Research, Cancer Treatment, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer, Living with Cancer

Transformative Impact of Immunotherapy Tops Cancer News

April 27, 2017 Nancy McCord 2 Comments

Diverse Hands Holding The Word Cancer — Immunotherapy brings breakthroughs to cancer treatment.

For decades, cancer has been the main focus of innumerable medical researchers. During 2016, immunotherapy for cancer was designated the top advance in the field for the second consecutive year.

The Rapid Rise of Immunotherapy Treatment

The announcement was made in Clinical Cancer Advances 2017, the 12th annual report from the American Society of Clinical Oncology (ASCO). Dr. Daniel F. Hayes, president of ASCO, presented the report to Congress during a recent meeting to request continued funding for cancer research.

According to Dr. Hayes, immunotherapy was a “promising theoretical treatment” less than 10 years ago. In a relatively short span of time, it has become a “standard of care” that has positively affected thousands of patients.

“Immunotherapy 2.0”

Just how much progress has been made in immunotherapy for cancer? Since 2011, a total of 15 immune-targeted therapies have been approved. That success combined with continued improvements in identifying candidates and overcoming resistance mechanisms, led ASCO to dub it “Immunotherapy 2.0.”

Dr. Hayes also stressed the importance of federal funding in maintaining the momentum in cancer research. One prominent development that has made a significant impact is the Cancer Moonshot program. Former Vice President Joe Biden took up the cause after his son Beau’s death from brain cancer.

Issels®: Ahead of the Curve

While the rest of the medical community is embracing the value of immunotherapy for cancer, we have been in the forefront of successfully treating patients by boosting their own immune systems. Visit our website to learn more about cancer vaccines, NK cells and our other non-toxic, individually tailored programs.

Cancer Research, Cancer Treatment, Cancer Vaccine, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer

Is There a Link Between Gut Bacteria and an Immunotherapy Response?

April 25, 2017 Nancy McCord

Questions on How Immunotherapy Will Work for You?

Could the path to fighting cancer go through your stomach? Researchers have found a surprising link between immunotherapy for cancer and the bacteria found in your gut.

The Varied Responses to Immunotherapy

While scientists had previously made the connection with mice, a team at the University of Texas MD Anderson Cancer Center recently made a breakthrough with the first study involving humans. The subjects included 233 patients with advanced melanoma.

A subset of 43 patients was on checkpoint inhibitors, one of the primary methods of immunotherapy for cancer. Out of this group, 30 responded to the treatment while 13 did not.

What made the difference? The researchers discovered that the 30 patients who responded had a wider variety of gut bacteria, particularly a specific type called Clostridiales, along with a higher concentration of the immune cells that fight cancer.

Strengthening the Immune System

According to Fred Ramsdell, vice president of research at the Parker Institute for Cancer Immunotherapy, it’s likely that exposure to a greater amount of bacteria during your lifetime results in a more robust immune system. Exactly why this happens is still a puzzle for now.

Experts are optimistic that this information will eventually be used to more effectively target patients who will respond to immunotherapy treatments. A clinical trial focusing on the microbiome is planned for later this year.

Immunotherapy for Cancer: The Issels® Approach

Our namesake, Dr. Josef M. Issels, pioneered non-toxic immunotherapy treatments and we carry on his legacy today. Contact us for more information about our individually tailored programs that are created to meet your individual needs.

Alternative Cancer Treatment, Cancer Research, Cancer Treatment, Immunotherapy, Immunotherapy for Cancer

Immunotherapy Trains Your Body to Fight Its Own Cancer

April 20, 2017 Nancy McCord 1 Comment

Your body’s immune system does an amazing job of protecting you from viruses, bacteria and other invaders. Tumor cells are able to avoid detection as foreign bodies, but immunotherapy for cancer is removing this advantage by boosting your body’s natural defenses.

How Cancer “Hijacks” the Immune System

When foreign cells invade your body, they carry proteins called antigens that trigger an immune response. Your system produces antibodies that bind with the antigens, which either neutralize the rogue cells on their own or alert T-cells to attack and destroy them.

While cancer cells also produce antigens, they manage to evade the normal process by hijacking the checkpoints that signal the immune system to attack. The cells remain undetected, allowing them to multiply as they continue to weaken the immune system.

Penetrating the Shield around Cancer Cells

Instead of using external treatments like radiation and chemotherapy to fight tumors, immunotherapy for cancer focuses on boosting the natural abilities of the immune system by “training” it to recognize and attack cancer cells. These methods include:

Drugs containing lab-made monoclonal antibodies that bind to cancer cell antigens and block the normal proteins that “disguise” them
Vaccines containing proteins that help the immune system recognize antigens on tumor cells

Issels®: A Personalized Approach

Immunotherapy for cancer has become a valuable alternative or supplement to traditional treatments, but each patient’s case is different. We use specialized testing to create an integrative treatment method that addresses your particular needs.

Alternative Cancer Treatment, Cancer Research, Cancer Treatment

New T Cell Tracking May Improve Immunotherapy Treatments

April 18, 2017 Nancy McCord

Another Step in Stopping Cancer — New T Cell Tracking May Improve Immunotherapy Treatments

T cells are in the front line of your immune system, multiplying rapidly to attack invading cells throughout your body. Immunotherapy for cancer took a big step forward with a study that found ways to track T cells in order to harness their specific tumor-fighting abilities.

Finding a Needle in a Haystack

Adoptive T cell transfer is a method of treatment in which T cells are harvested from a patient’s body and “groomed” to target cancer cells. They were then multiplied and placed back in the patient’s system where they could attack the tumor.

Unfortunately, there are a couple of roadblocks to this process. It’s difficult to know which of the thousands of different types of T cells are most effective against cancer, and cloning the cells can dilute or alter the tumor-killing properties of the originals.

Solving the Identification Problem

Researchers at Seattle’s Fred Hutchinson Cancer Research Center have discovered a process to help solve the former problem. A method called high throughput T cell receptor sequencing allowed the scientists to tag each T cell receptor with a “barcode,” enabling them to be tracked throughout the body.

The team gained valuable data when they applied the method to 10 patients with metastatic melanoma. Trials are now underway in search of more effective ways to extract and multiply T cells.

Immunotherapy for Cancer: Boosting Your Body’s Natural Defenses

For decades, Issels® has been a pioneer in the use of vaccines, NK cells and other non-toxic immunotherapy for cancer treatments. Visit our website to learn more about our individually tailored programs.

Alternative Cancer Treatment, Cancer Treatment, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer

Dr. Josef M. Issels Predicted the Future of Immunotherapy

April 13, 2017 Nancy McCord

Over the last few years, immunotherapy for cancer has become increasingly embraced by the medical community. But it was more than 20 years ago when our founder, Dr. Josef M. Issels, predicted the future of immunotherapy as an integrative and interdisciplinary approach.

A Groundbreaking Approach to Cancer Treatment

In a practice that spanned more than 40 years, Dr. Issels conducted research involving patients in the end stages of cancer, most of whom had exhausted all traditional methods of treatment. Results led to his pioneering a “holistic concept” of fighting cancer.

While traditional treatments focused on cancer as a disease unto itself, Dr. Issels believed it was a symptom of a larger disease affecting the entire person, body and mind. In such cases, the immune system is unable to perform its usual duties of defending against chronic development of malignant cells.

The breakdown of normal immune system functions centers on T-cells including Natural Killer (NK) Cells, which have the job of detecting and identifying foreign substances that enter the body. Without this normal barrier, malignant cells are free to multiply and form tumors.

Immunotherapy: An Integrative Method

Dr. Issels’ approach went beyond destruction and removal of tumors to address the main underlying causes of malignant cell development and immune system suppression in order to achieve long-term tumor remissions.

Traditional methods such as radiation and chemotherapy merely focus on the cancer cells and tumors. When they become part of an integrative treatment, including non-toxic immunotherapy, they can achieve better results with fewer side effects.

State-of-the-Art Immunotherapy for Cancer at Issels®

Our highly personalized non-toxic immunotherapy programs include Cancer Vaccines, Natural Killer (NK) Cells, Lymphokine-Activated Killer (LAK) Cells and Cytokines.

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