Tag Archives: Cancer Predisposition

Precision Cancer Treatments Use Genomics for Tumor Targeting

Genetic Profiling
Genetic Profiling

While cancer treatments continue to become more effective, physicians are still, all too often, faced with cases where a tumor fails to respond to any methods. Researchers are now optimistic about the possibility of genetic profiling as a way to pinpoint vulnerable treatment options in an otherwise stubborn tumor.

Oncologist Michael Pishvaian of Georgetown Lombardi Comprehensive Cancer Center compares locating the source of a tumor’s growth to “looking for a needle in a haystack.” The problem is that a cancer cell may hold hundreds of abnormally behaving genes, but it’s likely that only a few of them are actually fueling the tumor.

Dr. Pishvaian has first-hand experience with tumor profiling. In June 2013, he was treating a patient named Jen Morey for colon cancer using a conventional chemotherapy protocol. Unfortunately, after a couple of months the tumor was still growing at a rapid rate.

Faced with this roadblock, Dr. Pishvaian ordered a tumor profile test in an attempt to discover why treatment wasn’t working. He was astonished when the results indicated a genetic mutation found almost exclusively in breast cancer. 

Morey began undergoing treatment with a drug commonly used to target breast cancer gene mutations. Her condition quickly stabilized, and the new protocol was easier to tolerate because it attacks only cancer cells. A CT scan in December showed that the tumor has remained stable, and Morey was able to return to her critical-care nursing job in late January.

Our natural immuno-oncology treatments also use a personalized approach, including genomic testing, to create the most effective non-toxic protocols. Visit our website to learn more about our innovative cancer treatments.