Category Archives: Alternative Cancer Treatment

Could This Bacterial Molecule Stimulate the Immune System to Fight Cancer?

Get The Treatment You Need with Us!
Get The Treatment You Need with Us!

There’s a popular saying that goes, “Everything old is new again.” This may also hold true with immunotherapy for cancer, as researchers explore the possibility of enlisting your body’s ancient defenses against bacterial threats to fight tumors.

Going Back to the Future

A team at Fred Hutchinson Cancer Research Center in Seattle recently conducted a trial of an experimental drug on 15 patients with advanced sarcoma. The drug, known as G100, was based on a molecule called lipopolysaccharide that is carried within certain bacteria.

Lipopolysaccharide is unique to these organisms, so its presence has historically triggered a prompt and powerful inflammatory response. According to scientists, the pathway to this response dates back so far in the evolutionary cycle that it’s nearly identical in all animals.

Over a period of two to three months, participants received an injection of G100 directly into the tumor, along with a course of focused radiation. The injected tumors stopped growing, shrank or even disappeared in 14 of the 15 patients, while tumor growth throughout the body stopped in six of them.

Boosting the Body’s Immune System

Researchers are theorizing that the drug makes the tumor “hot” in terms of activating an immune response aimed specifically at the cancer cells. The next step involves combining G100 injections with an as-yet-undecided immunotherapy agent to see if the treatment can boost the cancer-fighting immune response throughout the body.

Using State-of-the-Art Methods to Fight Cancer

At Issels®, we stay up-to-date on all the latest advancements in immunotherapy for cancer. Contact us to learn more about our non-toxic, integrative treatment programs that are specifically designed for your individual needs.

Tumor Treating Fields (TTF) Emerge as a New Cancer Treatment

New Advances Are Being Made in Cancer Treatment
New Advances Are Being Made in Cancer Treatment Using TTFields

Brain cancer is one of the more difficult forms to treat, with the last advancement dating back more than 10 years. Today scientists are excited about the potential of tumor-treating fields (TTFields) as a means of “shocking” cancer cells.

Putting a “Charge” into Cancer

TTFields were first approved as a cancer treatment by the US Food and Drug Administration in 2011. The method of sending mild electrical fields through the scalp was originally used to treat glioblastoma, the most aggressive form of brain cancer that carries a two-year survival rate of approximately 30 percent.

NovoCure’s device, Optune, is a patient-controlled system that uses adhesive patches to deliver low-electric fields with a frequency of 200 kHz. The fields pulse through the skin, where they are thought to block the division of cancer cells.

TTFields in Action

There have been several subsequent trials of Optune that have generated positive results, but the most recent trial has been described as “landmark.” Neurologist Roger Stupp of Northwestern University led a group of researchers in a five-year study of patients newly diagnosed with glioblastoma.

Out of 695 participants, one-third were treated with oral chemotherapy alone while the other two-thirds had the oral treatment coupled with the Optune device. The two-, three-, four- and five-year survival rates were all significantly higher for the group that received the combination treatment.

Issels®: The Leader in State-of-the-Art Cancer Treatment

We’ve seen a significant number of patients achieve long-term remission after receiving our integrative immunotherapy programs. Contact us today to learn how Issels® has been ahead of the industry in the use of individually-developed immunotherapy protocols for cancer treatment.

The Cost of Some New Cancer Drugs Spiral Out of Reach for Some Patients

The Cost of Some Medications Is Rising
The Cost of Some Medications Is Rising

The last few years have brought exciting advances in immunotherapy for cancer, but innovation has come at a price … literally. Skyrocketing costs for cancer drugs are making them inaccessible for many who would benefit the most.

Cancer Drugs: The Price of Success

During the 10-year period between 2005 and 2015, Big Pharma’s pipeline of cancer drugs increased by 63 percent, with several reaching the market. As a result, the global market is projected to grow from $16.9 billion in 2015 to an astounding $75.8 billion in 2022.

But while competition generally serves to drive prices down, that’s not happening with the new cancer drugs. Factors such as market exclusivity, insurance plan structures and lack of head-to-head comparison studies combine to keep prices high.

One example is checkpoint inhibitors, which release the systemic “brakes” preventing the immune system from recognizing and attacking cancer cells. Bristol, Merck, Roche and Pfizer all have checkpoint inhibitors on the market, but each has an annual price tag approaching $150,000.

What’s the Answer?

Experts see no evidence that pharmaceutical companies, driven by the current free rein on pricing, are exploring more cost-effective solutions. President Donald Trump and lawmakers from both parties are prioritizing a search for methods to restrain spiraling cancer drug costs, ranging from more price negotiation to faster approval.

Issels® Leads the Field in Immunotherapy for Cancer

While the medical community and lawmakers grapple with the finances of immunotherapy for cancer, we have been successfully treating patients with individually developed non-toxic protocols for years. Contact us today to learn more about cancer vaccines, NK cells and other immunotherapy programs at Issels®.

Could Where You Live in Your Time Zone Affect Your Cancer Risk?

Does Your Time Zone Impact Cancer?
Tired When You Get Up? Could Your Time Zone Impact Cancer?

While the hour may be the same throughout a time zone, the degrees of sunlight and darkness are not. A recent study suggests that this quirk of nature may be linked to an increased cancer risk.

When Day Becomes Night

A research team at the National Cancer Institute was inspired by previous research showing slightly higher cancer risk among people who work the night shift. This finding was attributed to circadian disruption, which is a change in the body’s biological clock.

Shift workers experience extreme circadian disruption owing to almost complete reversal of day and night. The NCI researchers set out to see if the increased risk of cancer applied to minor disruptions in the body’s natural rhythms, referred to as social jet lag.

The most common example of social jet lag is rising at different times on work days and weekends, but the phenomenon also occurs with people living on either end of a time zone, where light and dark come at different times.

Effects of Social Jet Lag on Cancer Risk

After reviewing data from 4 million white adults who had been diagnosed with cancer, the NCI team found each five degrees of longitude toward the west resulted in an increased risk of three percent for men and four percent for women. Greater risk was also found specifically for breast cancer, prostate cancer and uterine cancer.

Issels®: Leading the Way in Immunotherapy for Cancer

Our Issels® clinic has been in the forefront of state-of-the-art immunotherapy for cancer treatments. Contact us to learn more about our personally tailored integrative programs.

Immunotherapy Trains Your Body to Fight Its Own Cancer

Immunotherapy Trains Your Body to Fight Its Own Cancer
Immunotherapy Trains Your Body to Fight Its Own Cancer

Your body’s immune system does an amazing job of protecting you from viruses, bacteria and other invaders. Tumor cells are able to avoid detection as foreign bodies, but immunotherapy for cancer is removing this advantage by boosting your body’s natural defenses.

How Cancer “Hijacks” the Immune System

When foreign cells invade your body, they carry proteins called antigens that trigger an immune response. Your system produces antibodies that bind with the antigens, which either neutralize the rogue cells on their own or alert T-cells to attack and destroy them.

While cancer cells also produce antigens, they manage to evade the normal process by hijacking the checkpoints that signal the immune system to attack. The cells remain undetected, allowing them to multiply as they continue to weaken the immune system.

Penetrating the Shield around Cancer Cells

Instead of using external treatments like radiation and chemotherapy to fight tumors, immunotherapy for cancer focuses on boosting the natural abilities of the immune system by “training” it to recognize and attack cancer cells. These methods include:

  • Drugs containing lab-made monoclonal antibodies that bind to cancer cell antigens and block the normal proteins that “disguise” them
  • Vaccines containing proteins that help the immune system recognize antigens on tumor cells

Issels®: A Personalized Approach

Immunotherapy for cancer has become a valuable alternative or supplement to traditional treatments, but each patient’s case is different. We use specialized testing to create an integrative treatment method that addresses your particular needs.

Contact us today to learn why Issels® has been a leader in the successful use of immunotherapy treatments.

New T Cell Tracking May Improve Immunotherapy Treatments

Another Step in Stopping Cancer
New T Cell Tracking May Improve Immunotherapy Treatments

T cells are in the front line of your immune system, multiplying rapidly to attack invading cells throughout your body. Immunotherapy for cancer took a big step forward with a study that found ways to track T cells in order to harness their specific tumor-fighting abilities.

Finding a Needle in a Haystack

Adoptive T cell transfer is a method of treatment in which T cells are harvested from a patient’s body and “groomed” to target cancer cells. They were then multiplied and placed back in the patient’s system where they could attack the tumor.

Unfortunately, there are a couple of roadblocks to this process. It’s difficult to know which of the thousands of different types of T cells are most effective against cancer, and cloning the cells can dilute or alter the tumor-killing properties of the originals.

Solving the Identification Problem

Researchers at Seattle’s Fred Hutchinson Cancer Research Center have discovered a process to help solve the former problem. A method called high throughput T cell receptor sequencing allowed the scientists to tag each T cell receptor with a “barcode,” enabling them to be tracked throughout the body.

The team gained valuable data when they applied the method to 10 patients with metastatic melanoma. Trials are now underway in search of more effective ways to extract and multiply T cells.

Immunotherapy for Cancer: Boosting Your Body’s Natural Defenses

For decades, Issels® has been a pioneer in the use of vaccines, NK cells and other non-toxic immunotherapy for cancer treatments. Visit our website to learn more about our individually tailored programs.