Category Archives: Cancer Survivors

After Cancer, Cancer Survivors

Scientists Find Similar Patterns in Multiple Types of Cancer Tumors

DNA
Genome Mapping

Scientists mapping cancer genomes have found surprising similarities between cancer tumors that originate in different organs. Their findings could one day lead to genetically engineered cancer treatments capable of targeting specific cancer genes. Advanced targeted cell therapy now allows cancer treatment specialists to target specific types of tissue at the cellular level; but this research breakthrough could lead to treatments that can turn on or off specific genes that initiate cancer and govern the growth of cancer cells. The discovery was made by biomolecular engineers working on the National Institutes of Health sponsored Cancer Genome Atlas which seeks to catalog the DNA of the thousands of tumor types included in the many varieties of cancer.

Shifting the focus of cancer research and treatment from the cellular to the genetic level could also lead to new treatments for cancers that have so far failed to respond to treatment, study co-author Josh Stuart of the University of California-Santa Cruz told the Los Angeles Times. Typically, the cancer drugs currently used in traditional medicine are designed to treat cancers of a specific organ or tissue type, such as breast cancer or lung cancer. Based on this new research, scientists hope to develop cross-cancer treatments that can cross organ and tissue boundaries to attack tumors with genetic similarities no matter where in the body they are located. In the future, cancer may be identified and treated by tumor type rather than body location.

The Cancer Genome Atlas project is expanding our knowledge of how cancerous tumors form and grow; but perhaps more importantly, it is allowing scientist to see connections between different types of cancer that could eventually lead to a cure for cancer.

Cancer Research, Cancer Survivors

Search for Genetic Links to Cancer Survival Could Lead to New Treatments

Cancer Advancements at the Genetic Level
Cancer Advancements at the Genetic Level

Researchers are taking a new look at why certain cancer patients survive usually fatal cancers by focusing on the genetic makeup of their cancer tumors. By studying these “miracle” survivors, researchers hope to discover how their bodies were able to target and kill cancer cells when others could not and apply that knowledge to the development of advanced targeted cancer therapies that could potentially increase the number of cancer survivors. Researchers believe that the key to cancer survival may lay hidden within the complex genetic composition of the cancer tumors themselves.

Spearheaded by the National Cancer Institute, Reuters reports that cancer researchers across the country have launched “super responder” initiatives designed to examine the role gene mutations play in the effectiveness of different drug protocols and cancer treatments. The study grew from a drug trial for patients with advanced bladder cancer conducted by Dr. David Solit, an oncologist at Memorial Sloan-Kettering Cancer Center in New York City. Dr. Solit wondered why one patient not only lived while others died but has remained cancer-free for three years. He discovered that a rare combination of two genetic mutations within her cancer tumor made the patient more receptive to the drug treatment. Solit has since created an outlier clinic to study such exceptional responses in other cancer patients.

The sequencing of the human genome has opened new avenues of cancer research and spurred the development of targeted cell therapies using both drugs and cancer vaccines. As the cost of gene sequencing continues to decrease, cancer treatment is expected to shift increasingly toward individualized treatment programs based on the patient’s unique genetic profile.

Alternative Cancer Treatment, Cancer Research, Cancer Survivors

Chemo to Arrest Childhood Cancers Comes with Adult Health Risks

Children Cancer Survivors at Risk for Adulthood Diseases
Children Cancer Survivors at Risk for Adulthood Diseases

A disturbing new study has found that the majority of childhood cancer survivors who undergo chemotherapy have a high risk of developing chronic, life-threatening diseases as adults. Equally disturbing is the fact that these problems go undetected until they reach advanced stages, placing childhood cancer survivors at critical risk. The unfairness of the situation is not lost on childhood cancer survivors.

In a landmark study of more than 1,7000 adults who were patients at St. Jude’s Children’s Research Hospital, two-thirds of chemotherapy patients developed chronic, life-threatening conditions as adults. Of those long-deferred chemo side effects, 90% of heart conditions and 55% of lunch problems had gone undetected by the individuals’ healthcare providers until revealed by the study.

Researchers traced part of the problem to failure to transfer medical records between pediatricians and general practitioners as childhood cancer survivors entered their adult years.

“Survivors of childhood cancer, once they graduate from pediatric programs, they’re going into a community where medical providers are not going to be aware of their unique health risks,” Dr. Melissa Hudson, the study’s co-author told CBS News. (Click the link to watch the report by Dr. John LaPook.)

With nearly 400,000 childhood cancer survivors in the U.S. alone, these delayed side-effects of chemotherapy present a serious health threat that has many questioning the use of traditional cancer treatment methods which bludgeon the body with chemotherapy, radiation and surgery. Growing concern about the effects of chemotherapy have more people considering the advanced alternative cancer treatments offered at Issels Integrative Oncology cancer treatment centers that work to build up the body’s immune system instead of tearing it down.

Cancer Survivors, Testimonials

Angelina Jolie Reveals Decision to Undergo Preventive Double Mastectomy

Breast Cancer Awareness
Breast Cancer Awareness

In a New York Times op-ed column, actress Angelina Jolie shocked many people by revealing that she had undergone preventive double mastectomy after learning she carries the BRCA1 gene which is known to significantly increase the risk of breast cancer and uterine cancer. Supported by husband Brad Pitt, Ms. Jolie’s decision to “be proactive and to minimize the risk as much as I could” was driven in large part by her mother’s long-term cancer battle and early death at the age of 56. In sharing her decision, Ms. Jolie lamented the fact that only one of her six children had the opportunity to know their grandmother before her death.

“My chances of developing breast cancer have dropped from 87% to under 5%,” Ms. Jolie said. “I can tell my children that they don’t need to fear they will lose me to breast cancer.”

Ms. Jolie is not the first high-profile celebrity to choose preventive double mastectomy. In 2008, actress Christina Applegate had both breasts removed after surviving breast cancer to prevent its return. However, Ms. Jolie represents a growing new movement among high-risk cancer patients to act before cancer strikes.

The desire to take aggressive preventive action before receiving a cancer diagnosis has been fueled by the discovery of genetic defects — BRCA1 and BRCA2 –directly linked to a high risk of breast cancer. Coupled with the high incidence of breast cancer among women, discovery that they carry a genetic marker for breast cancer seems to stoke the natural fear cancer provokes.

Preventive surgery is one way to deal with cancer fear, but it is not the only choice.

To be continued

Alternative Cancer Treatment, Cancer Survivors

Book Profiles Doctors Using Alternative Cancer Treatments to ‘Knockout’ Cancer

Alternative Healing
Alternative Healing

Better known today for her fitness videos and self-help books on diet and nutrition, Suzanne Somers rose to fame as ditzy blonde bombshell Chrissy on the 1977 hit sitcom Three’s Company. A frightening brush with breast cancer in 2001 changed Suzanne’s life.

After a lumpectomy to remove the tumor, her poor experience with radiation treatment led her to choose alternative cancer treatments over chemotherapy. Ten years after her successful recovery, Suzanne wrote Knockout: Interviews with Doctors Who Are Curing Cancer — and How to Prevent Getting It in the First Place (available on Amazon.com in paperback and Kindle).

Using her personal journey with breast cancer and her own experiences with alternative cancer treatments and alternative methods of cancer prevention as a springboard, in Knockout Suzanne puts the spotlight on innovative alternative cancer treatments and preventative measures that focus on building up the body and immune system.

In interviews with doctors who are successfully using alternative medical methods that are not yet part of Western medicine’s mainstream to knockout cancer, Suzanne explores the cutting-edge science and forward-reaching medical theories that are driving innovation in cancer treatment.

Among the alternative cancer treatments reviewed in Knockout are many of those  developed and employed at Issels Cancer Treatment Centers in Santa Barbara, California and Tijuana, Mexico, including modern integrative oncology, immunotherapy, cell therapy, cancer vaccines and gene-based therapies. In fact, Suzanne notes the role of our founder, Dr. Josef Issels, in pioneering integrative immunotherapy in the fight against cancer.

In Knockout, Suzanne says, “Cancer kills and continues to kill. But there is hope, and this book offers new choices.”  Issels Integrative Oncology is one of those new choices.

 

After Cancer, Cancer Survivors

More Suggestions for Creating a Cancer Survivor Manual

Daily Exercise
Daily Exercise

Cancer survivors that work with their cancer treatment team to create a plan for maintaining good health after cancer are most likely to thrive (see our previous post). Working with your Issels Integrative Oncology team to create a long-range lifestyle plan that addresses your physical, mental and nutritional health may both help your enjoy life to its fullest and prevent cancer recurrence.

Today we continue our suggestions for creating a cancer survivor’s manual:

  1. The basic tenets of living a healthy lifestyle should form the core of a cancer survival plan. Discuss an appropriate exercise plan with your doctor and exercise regularly. Start slow, increasing exercise every 2 to 3 weeks as your strength returns. A good goal for most people is 20 minutes of cardio exercise (walking, swimming, etc.) and 30 minutes of resistance training 3 to 5 days a week.
  2. With your medical team, develop a nutrition plan based on an anti-inflammatory diet that boosts your immune system. Many cancer survivor diet plans follow a basic Mediterranean diet which features plenty of antioxidant-rich fresh fruits and vegetables, fish high in omega-3s, nuts, beans, whole grains, lean meat and healthy oils. Maintaining a healthy diet can also help you lose weight, further decreasing your risk of cancer return.
  3. Add stress-reduction activities to your daily routine. Learn relaxation techniques such as mindful meditation or progressive muscle relaxation to help keep stress under control. Many cancer survivors find the support and encouragement they need in cancer support groups. Some cancer centers offer after-care programs for cancer survivors to help monitor health and help cancer survivors stay on track.