Nicotine Dependence May Be a First Pathway to Lung Cancer

Lung cancer is one of the most common types of cancers in the U.S., as well as a top cause of preventable cancer death. Although anyone can develop this type of cancer, certain individuals have a higher risk. Those who smoke or have nicotine dependence face a considerably increased risk of having lung cancer.

With more research focusing on improving outcomes for lung cancer through cancer immunotherapy and other treatment methods, scientists need to learn more about the causes of this disease. A research team at Dartmouth’s Geisel School of Medicine studied potential pathways that lead to lung cancer.

Nicotine Dependence as a Pathway

Researchers studied possible pathways that allow a chromosome called 15q25.1 to raise an individual’s risk of lung cancer. This chromosome has previously been identified as a genetic component that can increase lung cancer risks in some individuals. The research team found two pathways associated with this chromosome that could help explain how it leads to a higher lung cancer risk.

Nicotine dependence is linked to the first pathway that the researchers found. This finding has helped scientists better understand how lung cancer develops and why individuals with a history of smoking and certain genetic components face a significantly higher risk of having lung cancer. The second pathway is linked to biological processes, including those involving the immune system.

Improved Lung Cancer Treatments

The findings of this research could pave the way for improved treatments for lung cancer. Scientists can use these findings to come up with ways to block risky genetic variants, resulting in better outcomes for those with cancer. The results of this study might also be used to develop more effective ways to treat lung cancer using the body’s immune system or other methods.

For more information on cancer treatment and cancer immunotherapy, please contact Issels® today.

Low Fat Diets – Can They Help Prolong Life with Breast Cancer

study by Dr. Rowan Chlebowski, a medical oncologist at Harbor-UCLA Medical Center’s Los Angeles Biomedical Research Institute, shows that some women diagnosed with breast cancer who maintain a low-fat diet may reduce their risk of early death.

Research for women in the early stages of breast cancer specific to estrogen receptor-negative (ER-negative) cancer showed positive results. For this group, Dr. Chlebowski’s study showed a reduced risk of death factor of 36 percent over a 15-year study for patients who maintained a diet of low-fat food for five years after being diagnosed.

For women diagnosed with both ER-negative and progesterone-receptor negative (PR-negative) cancer, the results were even higher. Following the same five year low-fat diet regimen after initial diagnosis, patients experienced a 56 percent reduction in risk of death due to any cause.

The study included over 2,400 women ranging in age from 48 to 79 in the early stages of breast cancer. Of the 2,400 women, approximately 1,600 were diagnosed with ER-positive cancer while the remaining 800 were diagnosed with ER-negative or both ER and PR-negative cancer.

During the study, low-fat diets for half of the women was a requirement. Unannounced checks were made throughout the study. The other group was not required to maintain a low-fat diet. The study showed a lower death rate in the low-fat diet research group.

The study is the first where a low-fat diet over an extended period for cancer patients has been researched.

For information about how the Issels integrative immuno-oncology works in the treatment of breast cancer, contact Issels®. Established in 1951, Issels® has made a name for itself internationally for its success in the long-term remission of advanced tumors.

In Cancer Treatment? The Keto Diet May Have a Benefit

People are always looking for the next great diet in an effort to lose weight. The recently popular ketogenic diet could have some surprising benefits for patients undergoing cancer treatment.

The Warburg Effect

Cancer cells proliferate via the Warburg effect, named for the scientist who first advanced the idea. Fermentation is a process by which sugars are metabolized to provide energy for bacteria. Sauerkraut and yogurt are some of the more widely-known products of fermentation.

Unlike normal body cells, which derive their energy from mitochondria, cancer cells receive energy from fermentation of glucose within cytoplasm. When a cell starts getting energy from glucose, it can be the first sign of abnormal cell function that ultimately results in formation of a tumor.

The Ketogenic Diet: Starving Cancer Cells

A keto diet plan is low in carbohydrates and high in fat. The science behind it is based on a biological response that dates back to prehistoric times. When food was scarce, the body responded by shifting metabolic gears and using stored fat as fuel.

When the body’s supply of carbs is restricted, it shuts off the flow of glucose and other cancer-promoting fuels. As cancer cells become compromised, the body resumes its normal cellular signaling, putting the brakes on further tumor development.

The keto diet should not be considered a cure for cancer. However, it’s a valuable tool for use in conjunction with immunotherapy and other cancer treatment.

Immunotherapy and Nutrition: A Winning Combination

Good nutrition is a perfect complement for our non-toxic cancer treatment programs. Visit our website for more information about cancer vaccines and other individually created treatments.

Cancer Risks – What to Know

Cancer is effected by numerous and complex risk factors, making concepts related to calculating its risk a frequent subject of debate. Adding to this debate is a recent study looking at randomly mutating cells, specifically how they play a predominant role in cancer development. What does this say about your cancer risk? Issels® wants to help you put this new information in perspective.

Cancer and car accidents: They have a lot in common…

  • Trip length
    Comparing getting cancer to getting into a car accident, the length of your trip – your lifespan – increases your risk. The longer you live, the more the odds increase of your body randomly mutating cells, making this a significant risk factor – attributable to two-thirds of your total cancer risk in fact.
  • Road conditions
    Just as rain or snow can increase your risk of an accident, so too can conditions in your body and in your environment increase your risk of cancer.
  • Mechanical issues
    Bad brakes or worn tires can be seen as a metaphor for genetic factors, such as inherited mutations.

Reading the accident report
Despite this research, it can’t be stressed enough no single factor causes cancer. Two-thirds of car accidents are not related solely to trip length, but to a combination of road conditions, mechanical issues, and the like. For each “accident,” the major contributing factor will vary.

Accident prevention
Due to the large combination of risk factors, there are many opportunities for prevention, including addressing radiator issues (smoking), regular maintenance (early diagnostics and detection), and more.

Cancer spinning out of control? Contact Issels® today.

Cancer Treatment and the Impact on Cognitive Ability

Effective cancer treatment sometimes involves dealing with side effects and secondary symptoms. Here are some things you need to know about the possible effects of cancer and its treatment on cognitive abilities.

What Is Cognition?

Simply put, cognition is “the mental process of learning and understanding.” Cognitive thinking is what allows you to focus, process new information, solve problems, perceive spatial relationships and communicate via speaking and writing.

Cognitive Problems Related to Traditional Cancer Treatment

Problems involving learning and memory are common signs of cognitive impairment due to cancer. Specific problems can include:

– Inability to complete tasks

– Failure to recognize familiar objects

– Loss of focus and concentration

– Difficulty with money management, such as paying bills

– Lack of motivation

– Disorganized behavior and/or thinking

Other Factors Contributing to Cognitive Problems

States of mental and physical well-being are deeply intertwined. Cancer patients and survivors may find that the following issues also impact cognitive abilities:

– Age

– Overall weakness or frailty

– Drug and alcohol use

– Chemotherapy and other cancer treatment

– Other diseases or illnesses

– Being postmenopausal

Restoring Cognitive Abilities After Cancer Treatment

Researchers are studying the use of certain drugs in treating cognitive problems, but a pharmaceutical solution is still in the future. Many patients have found these natural methods to be helpful:

– Movement therapy, such as tai chi or yoga, that emphasizes the mind-body connection

– Learning new ways to absorb information

– Using calendars, tech devices or other tools to stay organized

– Activities such as gardening or caring for pets that establish focus

Take a New Look at the Integrative Non-Toxic Cancer Treatment at Issels®

Our personalized cancer treatment methods avoid the common side effects that can affect your overall wellness. Contact us for more information.

Cancer Risks Are Linked to Cell Growth

Cancer is affected by numerous and complex risk factors, making concepts related to calculating its risk a frequent subject of debate. Adding to this debate is a recent study looking at randomly mutating cells, specifically how they play a predominant role in cancer development. What does this say about your cancer risk? Issels® wants to help you put this new information in perspective.

Cancer and car accidents: They have a lot in common…

  • Trip length
    Comparing getting cancer to getting into a car accident, the length of your trip – your lifespan – increases your risk. The longer you live, the more the odds increase of your body randomly mutating cells, making this a significant risk factor – attributable to two-thirds of your total cancer risk in fact.
  • Road conditions
    Just as rain or snow can increase your risk of an accident, so too can conditions in your body and in your environment increase your risk of cancer.
  • Mechanical issues
    Bad brakes or worn tires can be seen as a metaphor for genetic factors, such as inherited mutations.

Reading the accident report
Despite this research, it can’t be stressed enough no single factor causes cancer. Two-thirds of car accidents are not related solely to trip length, but to a combination of road conditions, mechanical issues, and the like. For each “accident,” the major contributing factor will vary.

Accident prevention
Due to the large combination of risk factors, there are many opportunities for prevention, including addressing radiator issues (smoking), regular maintenance (early diagnostics and detection), and more.

Cancer spinning out of control? Ask about the Issels Cancer Treatment. Contact Issels® today.

Individualized Cancer Treatment