Tag Archives: Fighting Cancer

Immunotherapy is the Hot Buzz in the World of Cancer Research Publications

Could Immunotherapy Be Your Miracle Treatment?
Cancer Immunothereapy in the News

Thanks to rapid and effective developments, immunotherapy for cancer continues to be a hot topic in the medical community. A recent analysis shows the explosive growth of this subject in academic and industrial publications.

Immunotherapy for Cancer in the News

Results of the analysis conducted by Drs. Enal Razvi and Gary Oosta were published in Genetic Engineering & Biotechnology News. Data was based on publications in the broad space of cancer immunology, which have seen exponential growth from zero in the early ’70s to more than 600 in the past year.

While there has been a clear increase in quantity, what about qualitative measures? A word cloud corresponding to titles and abstracts shows that the major areas of focus are “cancer,” “immunotherapy,” “cells,” “immune” and “tumor.”

Drilling down to find the key components of these publications, the most commonly mentioned one is “dendritic cells,” which play a vital role in initiating the immune response. “Cell death” (apoptosis) has generated 33 percent annual growth.

What Does the Future Hold?

Drs. Razvi and Oosta drew the following conclusions:

  • Understanding in vivo mechanisms and pathways driving immunological cascades is crucial for continued progress.
  • Companies will continue clinical trials, both individually and in collaboration with others.
  • Immunotherapy for cancer will eventually use biomarkers to identify which populations and sub-populations are the optimum candidates for specific treatments.

Individualized Blueprints for Immunotherapy

At Issels®, our integrative therapies are personalized based on each patient’s lifestyle and genetic makeup as well as the tumor microenvironment. Contact us today to hear success stories from patients of all ages who have dealt with leukemia, melanoma and other forms of cancer.

Research Being Done to Boost Immunotherapy Response in the Tumor Microenvironment

New Smart Blood Test Allows Doctors to Tailor Treatment
The Microenvironment

Cancer cells often proliferate due to their ability to evade the body’s natural defense system. Immunotherapy for cancer eliminates this advantage by boosting the response of immune cells, but researchers have discovered a possible roadblock: a limited amount of cellular “fuel.”

Running on Empty

A team at the University of Pittsburgh conducted a study to determine why treated T cells lose mitochondrial function once they are reintroduced to the tumor environment. They confirmed that the reaction is definitely a result of proximity to the tumor and not a side effect of activation.

Data obtained during testing showed that the tumor microenvironment contains signals that repress oxidative metabolism in T cells. In effect, the cells starve from lack of energy.

Stoking the Flames

The study, published last August in the journal Immunity, found that T cells suffer a progressive loss of a PPAR-gamma coactivator that programs mitochondrial function. Laboratory testing on rats showed that just as T cells can be treated to better detect and fight tumor cells, they can be treated with the coactivator to maintain effective metabolism levels.

Dr. Greg M. Delgoffe, leader of the University of Pittsburgh team, has joined with other scientists to develop new methods of immunotherapy for cancer using the study’s results. Strategies include incorporating commonly used drugs along with further T cell modification to stimulate metabolism.

Issels®: The Leader in State-of-the-Art Immunotherapy

Our innovative, personally tailored therapies fight cancer by focusing on both the tumor and its microenvironment for more effective treatment. Contact us to learn more about our non-toxic protocols such as cancer vaccines and NK cells.

Common Digestive Problems during Cancer Treatment, What to Do to Solve Them

Waking from Cancer Related Digestive Issues
Waking from Cancer Related Digestive Issues

Going through cancer treatment can feel as though you’re fighting an uphill battle. Several different kinds of problems may arise during your course of treatment, but there are ways to lessen their effects or eliminate them entirely. Your friends at Issels® have put together a list of three cancer treatment tips that can help you along the way, allowing you to remain comfortable as you get back to feeling better.

  1. Changing Appetites

A decrease in appetite is normal immediately following an intensive round of treatment. Counteracting this might include eating several small meals a day, as well as eating foods with a high caloric value. Staying hydrated is important even if you’re not eating a lot, which usually means drinking lots of water.

  1. Constipation

Fruits, fiber, vegetables and fluids are what you need to consume if you are having constipation problems. Coupled with a lack of appetite, you might find it hard to get your body moving, and in extreme cases you should consult with your doctor about finding a laxative that will work best for you.

  1. Diarrhea

If your bowel movements are too frequent and too loose, you may want to cut down on the foods mentioned above, though you should still be drinking plenty of fluids. Constant diarrhea should be discussed with your doctor, who may put you on a prescription or recommend an over-the-counter medication to help with it.

To find out more about how Issels® can help treat cancer in any stage or for more cancer treatment tips, give us a call at 1-888-447-7357 or use the contact form on our website.

American Institute for Cancer Research List Cancer-Fighting Foods

Cancer Fighting Foods
Cancer Fighting Foods

Do you need more motivation to consume a healthy diet? According to the American Institute for Cancer Research (AICR), excess body weight is a cause of more than 130,000 new cases of cancer in the United States each year.

Consuming nutritious plant-based foods, including fruits, vegetables, whole grains and beans, provides a double-whammy against cancer. Fewer calories mean no weight gain, while the vitamins and minerals are strong tools against developing cancer.

What’s on Your Grocery List?

Fortunately, there’s a wide variety of delicious foods to choose from. Here are some of the products that rank high on AICR’s list.

  • Dark green leafy vegetables such as kale, spinach and romaine lettuce contain carotenoids that attack free radicals, which are unstable molecules that cause cell and tissue damage.
  • Tomatoes get their red color from an antioxidant called lycopene. They’re also rich in fiber, which protects against colorectal cancer.
  • Coffee has gained a bad reputation with some, but it’s actually full of antioxidants that may become more potent during the roasting process.
  • Kidneys, black beans and other legumes are a good source of fiber and protein. They also contain a resistant starch used by “good” bacteria in the colon to manufacture protective short-chain fatty acids.
  • Blueberries are considered one of the “superfoods” that have some of the highest antioxidant content.

Good Nutrition and Immunotherapy for Cancer: A Powerful Combination

At our Issels® center, diet and other lifestyle factors are taken into consideration when creating our personalized immunotherapy for cancer treatments. Contact us for more information about non-toxic protocols such as cancer vaccines and NK cells.

National Cancer Institute Advances Research on Cancer Diagnosis

Advances In Fighting Cancer
Advances In Fighting Cancer

Diagnosing cancer goes far beyond simply confirming its existence. The effectiveness of immunotherapy for cancer and other forms of treatment improves greatly with timely and accurate information from high-tech diagnostic tools.

National Cancer Institute Spearheads Diagnostic Research

The National Cancer Institute (NCI) supports development of sophisticated equipment and testing through its Division of Cancer Treatment and Diagnosis. Ongoing programs maintained by the division include:

  • Program for the Assessment of Clinical Cancer Tests (PACCT), which aims to break down barriers that hinder accurate diagnostic testing.
  • Strategic Partnering to Evaluate Cancer Signatures (SPECS), which looks for ways to use data from molecular analyses to improve care and treatment of cancer patients.
  • Cancer Imaging Program (CIP), which focuses on non-invasive imaging techniques to diagnose cancer along with specific subsets.

Why Diagnostic Procedures are Important

In addition to identifying the presence and extent of cancer, diagnostic tools are useful throughout the course of a patient’s treatment. Healthcare teams use them to recognize and classify specific genetic changes, determine the best course of treatment, and monitor patients for recurrence of cancer cells.

Ironically, as the effectiveness of tools and techniques has increased, so has the number of over-diagnosed tumors that are unlikely to have serious consequences. Researchers are also concentrating on ways to more accurately evaluate the data being provided by diagnostics.

Issels® is in the Forefront of Modern Diagnostic and Treatment Techniques

Our Issels® team stays up-to-date on the most advanced diagnostic methods as well as state-of-the-art immunotherapy for cancer treatments. Contact us today to learn how our personally tailored treatment protocols have helped patients with all forms of cancer.

National Cancer Institute: Environmental Cancer Causing Agents Act at the DNA Level

Cancer Can Be Caused at The DNA Level
Cancer Can Be Caused at The DNA Level

Reducing your risk of cancer involves more than eating a healthy diet that is low in fat and high in nutrients. Exposure to certain environmental factors can set the stage for development of cancer by actually causing damage to your DNA.

Everyday Exposure to Cancer-Causing Elements

As explained by the National Cancer Institute (NCI), cancer occurs when genes mutate in such a way that cell replication and growth is severely altered. While this can occur naturally, specific elements of the environment have been found to inflict this type of damage on DNA.

Here are some of the environmental carcinogens that present the biggest risk of causing cancer. Some are difficult to avoid, but others are more easily controlled.

  • Aflatoxins, which are associated with risk of liver cancer, are produced by mold that’s most often found on crops such as corn and peanuts. Aspergillus is the most common variety of aflatoxin-producing mold.
  • Tobacco smoke is one of the more highly publicized carcinogens. One obvious solution is to quit smoking or never start, but second-hand smoke is harder to avoid.
  • Asbestos releases minute fibers into the air when damaged. Ingesting these fibers can lead to lung cancer or mesothelioma. The Occupational Health and Safety Administration has instituted strict measures governing the use of asbestos, which have greatly reduced its risk.

NCI emphasizes that exposure to these elements doesn’t guarantee cancer. Factors such as length of exposure and individual genetic makeup also play a part.

Issels® and Non-Toxic Immunotherapy for Cancer

At Issels®, we understand that lifestyle and environment make each patient’s case unique. Contact us to learn more about our individually tailored immunotherapy for cancer.