All posts by Nancy McCord

Careful with Antibiotics During Cancer Treatment!

Doctors always take care when prescribing combinations of drugs due to possible negative interactions. It’s not surprising that mounting evidence indicates the complex balance of targeted cancer treatment can be upset by use of antibiotics.

Disrupting the Body’s Natural Defenses

According to results of a study conducted at the Georgia Cancer Center, this problem stems from the effect of antibiotics on gut microbiota, the network of bacteria, viruses and fungi that resides in the digestive tract. These “good” germs aid with digestion and protect our system from “bad” germs.

In the process of killing off microorganisms that cause infections, antibiotics also destroy large amounts of gut bacteria. As a result, patients on a course of antibiotics often experience nausea, vomiting, diarrhea and other gastrointestinal symptoms.

The Connection Between Gut Bacteria and Cancer Treatment

Dr. Gang Zhou, corresponding author of the study, explained that certain bacteria in the microbiota are necessary to activate the T-cells involved in cancer treatment known as adoptive T-cell therapy. A newer form of treatment called CAR T-cell therapy appears to be resistant to the antibiotic effect because it works on its own, with little reliance on the immune system.

Co-author Dr. Locke Bryan pointed out that antibiotics are often used in conjunction with chemotherapy. This traditional cancer treatment lowers white blood cell counts to the point where there’s no defense against bacteria, and an infection can be lethal to an already weakened immune system.

Individualized Treatment Plans for Specific Needs

Our personally tailored immunobiologic core treatments are designed to remove or repair factors that inhibit the body’s natural defense mechanisms. Contact us for more information.

New Urine Test May Allow Dismissal of Prostate Biopsy

Urine samples can be used to detect a wide range of conditions such as diabetes, pregnancy and drug abuse. Researchers are now working on developing a urine “sniff test” that can help reduce the number of unnecessary prostate cancer biopsies.

Diagnosing Prostate Cancer

Among men in the United States, cases of prostate cancer are second only to skin cancer. Approximately one in seven men will require cancer treatment for the disease at some point in their lifetime.

One of the signs of prostate cancer is an elevated blood level of prostate-specific antigen (PSA). Unfortunately, unrelated conditions can also cause high PSA levels, so a biopsy is necessary for a specific diagnosis.

The Nose Knows

A study showed that dogs could smell the presence of volatile organic compounds (VOCs) in the urine of men with prostate cancer at 98 percent accuracy, prompting a team at Indiana University-Purdue University Indianapolis to investigate further.

After collecting urine samples from 100 men undergoing prostate biopsies and neutralizing the pH to prevent degradation, the team discovered that a particular set of VOCs was present in 90 percent of the men who were diagnosed with prostate cancer but absent in the men who were cancer-free.

The researchers plan to validate their findings with a large-scale study and comparison to the results with dogs. If all goes well, they project that a version of the sniff test will be available for clinical use within a few years.

Personalized Cancer Treatment at Issels®

Our individually developed immunotherapy programs are based on special testing to identify your particular needs. Contact us for more information.

Living with Cancer May be a New Normal

Not so long ago, a diagnosis of cancer was the worst news a patient could hear. Flash forward to today when, thanks to remarkable improvements in cancer treatment, patients are learning to live with the disease as their “new normal.”

Liz Burke: One Woman’s Story

In TheJournal.ie, an Irish news website, a woman named Liz Burke shared her experiences in honor of Daffodil Day, a fundraiser for the Irish Cancer Society. Liz was originally diagnosed with breast cancer in 2007.

After a lumpectomy, Liz underwent a course of chemotherapy followed by another of radiotherapy. She demonstrated her sense of humor by relating a story about purchasing a wig to cover her baldness and finding it one day in the mouth of her Jack Russell terrier.

Two years later, Liz’s doctor discovered that breast cancer cells had metastasized to her liver. This triggered another nine months of chemotherapy followed by two years of maintenance, but the good news is that the tumors became inactive.

Finally, one more blow. After five years, the breast cancer metastasized again, this time resulting in a brain tumor. Liz had surgery to remove the tumor and radiotherapy treatment afterwards.

“People Survive Cancer”

These days Liz follows a regular schedule of MRIs, CT scans and weekly infusions. Her message? “People can live quite happily alongside cancer.” Liz believes we’re lucky to live in a time when so much progress is being made with new and effective cancer treatment.

Issels®: There IS Life After Cancer

Many of our patients at Issels® have similar stories of hope and recovery. Visit our website to read and hear their testimonials.

Nicotine Dependence May Be a First Pathway to Lung Cancer

Lung cancer is one of the most common types of cancers in the U.S., as well as a top cause of preventable cancer death. Although anyone can develop this type of cancer, certain individuals have a higher risk. Those who smoke or have nicotine dependence face a considerably increased risk of having lung cancer.

With more research focusing on improving outcomes for lung cancer through cancer immunotherapy and other treatment methods, scientists need to learn more about the causes of this disease. A research team at Dartmouth’s Geisel School of Medicine studied potential pathways that lead to lung cancer.

Nicotine Dependence as a Pathway

Researchers studied possible pathways that allow a chromosome called 15q25.1 to raise an individual’s risk of lung cancer. This chromosome has previously been identified as a genetic component that can increase lung cancer risks in some individuals. The research team found two pathways associated with this chromosome that could help explain how it leads to a higher lung cancer risk.

Nicotine dependence is linked to the first pathway that the researchers found. This finding has helped scientists better understand how lung cancer develops and why individuals with a history of smoking and certain genetic components face a significantly higher risk of having lung cancer. The second pathway is linked to biological processes, including those involving the immune system.

Improved Lung Cancer Treatments

The findings of this research could pave the way for improved treatments for lung cancer. Scientists can use these findings to come up with ways to block risky genetic variants, resulting in better outcomes for those with cancer. The results of this study might also be used to develop more effective ways to treat lung cancer using the body’s immune system or other methods.

For more information on cancer treatment and cancer immunotherapy, please contact Issels® today.

Low Fat Diets – Can They Help Prolong Life with Breast Cancer

study by Dr. Rowan Chlebowski, a medical oncologist at Harbor-UCLA Medical Center’s Los Angeles Biomedical Research Institute, shows that some women diagnosed with breast cancer who maintain a low-fat diet may reduce their risk of early death.

Research for women in the early stages of breast cancer specific to estrogen receptor-negative (ER-negative) cancer showed positive results. For this group, Dr. Chlebowski’s study showed a reduced risk of death factor of 36 percent over a 15-year study for patients who maintained a diet of low-fat food for five years after being diagnosed.

For women diagnosed with both ER-negative and progesterone-receptor negative (PR-negative) cancer, the results were even higher. Following the same five year low-fat diet regimen after initial diagnosis, patients experienced a 56 percent reduction in risk of death due to any cause.

The study included over 2,400 women ranging in age from 48 to 79 in the early stages of breast cancer. Of the 2,400 women, approximately 1,600 were diagnosed with ER-positive cancer while the remaining 800 were diagnosed with ER-negative or both ER and PR-negative cancer.

During the study, low-fat diets for half of the women was a requirement. Unannounced checks were made throughout the study. The other group was not required to maintain a low-fat diet. The study showed a lower death rate in the low-fat diet research group.

The study is the first where a low-fat diet over an extended period for cancer patients has been researched.

For information about how the Issels integrative immuno-oncology works in the treatment of breast cancer, contact Issels®. Established in 1951, Issels® has made a name for itself internationally for its success in the long-term remission of advanced tumors.

In Cancer Treatment? The Keto Diet May Have a Benefit

People are always looking for the next great diet in an effort to lose weight. The recently popular ketogenic diet could have some surprising benefits for patients undergoing cancer treatment.

The Warburg Effect

Cancer cells proliferate via the Warburg effect, named for the scientist who first advanced the idea. Fermentation is a process by which sugars are metabolized to provide energy for bacteria. Sauerkraut and yogurt are some of the more widely-known products of fermentation.

Unlike normal body cells, which derive their energy from mitochondria, cancer cells receive energy from fermentation of glucose within cytoplasm. When a cell starts getting energy from glucose, it can be the first sign of abnormal cell function that ultimately results in formation of a tumor.

The Ketogenic Diet: Starving Cancer Cells

A keto diet plan is low in carbohydrates and high in fat. The science behind it is based on a biological response that dates back to prehistoric times. When food was scarce, the body responded by shifting metabolic gears and using stored fat as fuel.

When the body’s supply of carbs is restricted, it shuts off the flow of glucose and other cancer-promoting fuels. As cancer cells become compromised, the body resumes its normal cellular signaling, putting the brakes on further tumor development.

The keto diet should not be considered a cure for cancer. However, it’s a valuable tool for use in conjunction with immunotherapy and other cancer treatment.

Immunotherapy and Nutrition: A Winning Combination

Good nutrition is a perfect complement for our non-toxic cancer treatment programs. Visit our website for more information about cancer vaccines and other individually created treatments.