Category Archives: Cancer Research

Alternative Cancer Treatment, Cancer Research, Cancer Survivors, Cancer Treatment, Cancer Vaccine, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer, Living with Cancer, Uncategorized

Tips for Coping with a New Cancer Diagnosis

Do you Have or Know Someone Who is Currently Experiencing a Hard to Treat Cancer? There is Hope!
Do you Have or Know Someone Who is Currently Experiencing a Hard to Treat Cancer? There is Hope!

When you receive a diagnosis of cancer, your mental and emotional adjustment can make a difference during your course of immuno oncology treatment. Unfortunately, most people have no frame of reference for coping with such news.

The American Cancer Society offers helpful tips for coming to terms with a cancer diagnosis and continuing to live life to the fullest.

Follow Your Own Path

Your situation is unique. Others may offer ideas of what has worked for them, but don’t feel obligated to follow them to the letter. View these tips as suggestions and try out different methods to find your own best solution.

Learn About Your Cancer

Knowledge is power. The unknown is often more frightening than the reality, so take time to educate yourself about your type of cancer and the various treatment options that are available.

Stay Active

The link between exercise and mood is well-documented. Physical activity stimulates production of endorphins, which are natural mood elevators. Consult with your doctor to make sure you’re not overdoing it.

Let Your Feelings Out

Many people believe that fear, anger and other negative emotions must remain hidden, but that can make your situation even harder to bear. Talk to friends and family, join a support group or try an artistic outlet such as writing or painting.

Be Kind to Yourself

Make a point each day of doing something that makes you happy, whether it’s meeting a friend for lunch or simply meditating for 15 minutes.

Issels®: Immuno Oncology Personally Created for You

Our non-toxic immunotherapy programs are individually designed to meet your specific needs. Contact us to learn more.

Alternative Cancer Treatment, Cancer Research, News, Uncategorized

New Immunotherapy Drug Combination Fails to Stop Cancer’s Progression

New Immunotherapy Drug Combination Fails to Stop Cancer's Progression
New Immunotherapy Drug Combination Fails to Stop Cancer’s Progression

Scientists have embraced immuno oncology research as an avenue for more effective cancer treatments. Unfortunately, the field took a temporary hit recently when Incyte pulled the plug on its latest immunotherapy drug trial.

Arming the Body’s Immune System

Incyte had high hopes for epacadostat, which works as an IDO inhibitor. IDO is an enzyme found in the body that prevents T cells in the immune system from attacking cancer cells.

In the trial, epacadostat was paired with Keytruda, a phenomenally successful immunotherapy drug from Merck. Keytruda is a checkpoint inhibitor that helps T cells recognize cancer cells, which often evade detection.

It was hoped that epacadostat would boost the effectiveness of Keytruda when taken alone. But not only did epacadostat fail to stop the progression of cancer, it had no positive effect on overall survival rates.

Is There Still Hope for Epacadostat?

While the original trial failed against melanoma, Incyte is hoping to conduct further tests with epacadostat in treating other forms of cancer. As explained by Dr. Jason Luke, an oncologist at the University of Chicago, the patient sample may have been too broad.

According to Dr. Luke, immunotherapy benefits patients with T cell-inflamed tumors. The key is to test epacadostat on patients who have a natural immune response, which can be determined via RNA-based sequencing.

Yale University oncologist Dr. Roy Herbst says the setback will not affect the enthusiasm for immunotherapy. He emphasizes that these cancer treatments are not a one-size-fits-all solution.

Personalized Immuno Oncology Programs at Issels®

Our non-toxic immunotherapy programs have always been tailored individually to address each patient’s specific needs. Contact us for more information.

Cancer Research, News

Losing Too Much Weight When You Are Over 60 May Signify Cancer

Losing Too Much Weight When You Are Over 60 May Signify Cancer
Losing Too Much Weight When You Are Over 60 May Signify Cancer

As the obesity problem in our society has grown, doctors have recommended programs for their patients to lose weight through healthy eating and moderate exercise. But immuno oncology experts warn that unexplained weight loss in people over the age of 60 can be a sign of cancer.

What Is the Relationship between Unexplained Weight Loss and Cancer?

With cancer survival rates that rank well below those of many comparable countries, Great Britain has been searching for ways to improve early detection and treatment. A research team led by the Universities of Oxford and Exeter set out to quantify the connection between unexplained weight loss and cancer.

The team reviewed 25 studies involving 11.5 million patients. Their major findings include:

– Men over the age of 60 with unexplained weight loss had a 14.2 percent risk of cancer, more than double the 6.7 percent risk of women in the same age group.

– Weight loss is a primary factor in prostate cancer, the most common form occurring in men, which accounts for the gender disparity.

– Unexpected weight loss was found to be the second-highest risk factor in colorectal, lung, renal and pancreatic cancers.

Improving Access to Early Testing

There are currently no guidelines for doctors regarding weight loss and how it pertains to cancer. Dr. Richard Roope of the Royal College of GPs expressed hope that this study will help improve access to more accurate diagnostic tools.

Issels®: The Leader in Effective Immuno Oncology

Our personally designed, non-toxic immuno oncology programs have been successful with many patients diagnosed with advanced or therapy-resistant cancers. Contact us today for more information.

Cancer Research, Cancer Survivors, Cancer Treatment, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer, Uncategorized

Immunotherapy and Gastric Cancers – What to Know

Immunotherapy and Gastric Cancers
Immunotherapy and Gastric Cancers

Immunotherapy and other targeted methods have shown promise in effectively fighting gastric and gastroesophageal junction (GSJ) cancers. At a recent summit meeting, Dr. Andrew Ko, professor of medicine at the University of California, San Francisco, discussed cancer treatment for gastric and GSJ cancers as well as current challenges.

Checkpoint Inhibitors and Gastric Cancers

In terms of recent developments, Ko pointed to last year’s FDA approval of pembrolizumab as a turning point in the treatment of advanced cancers. Pembrolizumab (trade name Keytruda) is a checkpoint inhibitor used on cancers with positive expression of PD-L1, a protein that enables cancer cells to avoid attack by the immune system.

Ko also mentioned nivolumab (trade name Opdivo), another checkpoint inhibitor. Nivolumab is used for melanoma and lung cancers, but clinical trials have shown that it has potential as a secondary treatment following chemo-radiation and surgery for patients with certain GEJ cancers.

Unfortunately, cases of upper gastrointestinal cancers continue to rise in Western countries. Ko explained that, despite improvements in immunotherapy cancer treatment, many patients are still non-responders, creating continued urgency in finding additional methods.

The Future of Gastric Cancer Treatment

According to Ko, immunotherapy still holds the greatest interest for cancer researchers.

– Studies are exploring combinations of drugs, such as nivolumab plus ipilimumab (trade name Yervoy).

– Other studies are focused on moving targeted agents from secondary to first-line treatments.

Immunotherapy for Advanced and Therapy-Resistant Cancers

Immunotherapy programs at Issels® are individually developed to help your body’s own immune system attack and destroy cancer cells. Contact us to learn why our personalized, non-toxic treatments have helped patients of all ages and types of cancer.

Alternative Cancer Treatment, Cancer Research, Cancer Treatment, Cancer Vaccine, Immuno-Oncology, Immunotherapy, Immunotherapy for Cancer, Living with Cancer, Uncategorized

New Vaccine for Ovarian Cancer Improves Life Expectancy

There is New Hope for Ovarian Cancer Treatment
There is New Hope for Ovarian Cancer Treatment

No two cases of cancer are the same, so scientists are finding that cookie-cutter cancer treatment is not always the best solution. According to a recently published study, a personalized vaccine has shown promise for boosting ovarian cancer survival rates.

Ovarian Cancer: The “Silent Killer”

An international team of researchers conducted the study of ovarian cancer, often referred to as a “silent killer” because it’s usually in an advanced stage by the time of diagnosis. Chemotherapy plus surgery is the conventional course of treatment, but team member Dr. Lana Kandalaft notes that 85 percent of patients experience recurrence.

Matching Cancer Treatment to Patient

Immunotherapy is a form of treatment that uses a patient’s own immune system to attack and kill cancer cells. In this case, researchers created a vaccine by harvesting a patient’s immune cells, then exposed them to cells from the tumor so they could be identified.

All patients in the study were treated with a combination of immunotherapy drugs, while a certain number also received the vaccine. After one year, the vaccinated group had a survival rate of 100 percent compared to 60 percent of the control group.

Results continued to be encouraging after two years. The vaccinated group showed a survival rate of 78 percent, while the rate dropped to 44 percent with patients receiving drugs alone.

Issels®: A Pioneer in Personalized Cancer Treatment

Our founder, Dr. Josef Issels, performed groundbreaking work developing immunotherapy as an integrative and holistic form of cancer treatment. Visit our website for more information about how we are continuing his legacy of helping patients with advanced and therapy-resistant cancers achieve long-term remission.

Alternative Cancer Treatment, Cancer Research, Cancer Treatment, Immuno-Oncology, Immunotherapy for Cancer, Living with Cancer, Uncategorized

Cancer Treatment and the Impact on Cognitive Ability

Immunotherapy is Changing Cancer Treatment Again in Exciting New Ways
Cancer Treatment and the Impact on Cognitive Ability

Effective cancer treatment sometimes involves dealing with side effects and secondary symptoms. Here are some things you need to know about the possible effects of cancer and its treatment on cognitive abilities.

What Is Cognition?

Simply put, cognition is “the mental process of learning and understanding.” Cognitive thinking is what allows you to focus, process new information, solve problems, perceive spatial relationships and communicate via speaking and writing.

Cognitive Problems Related to Cancer

Problems involving learning and memory are common signs of cognitive impairment due to cancer. Specific problems can include:

– Inability to complete tasks

– Failure to recognize familiar objects

– Loss of focus and concentration

– Difficulty with money management, such as paying bills

– Lack of motivation

– Disorganized behavior and/or thinking

Other Factors Contributing to Cognitive Problems

States of mental and physical well-being are deeply intertwined. Cancer patients and survivors may find that the following issues also impact cognitive abilities:

– Age

– Overall weakness or frailty

– Drug and alcohol use

– Chemotherapy and other cancer treatment

– Other diseases or illnesses

– Being postmenopausal

Restoring Cognitive Abilities

Researchers are studying the use of certain drugs in treating cognitive problems, but a pharmaceutical solution is still in the future. Many patients have found these natural methods to be helpful:

– Movement therapy, such as tai chi or yoga, that emphasizes the mind-body connection

– Learning new ways to absorb information

– Using calendars, tech devices or other tools to stay organized

– Activities such as gardening or caring for pets that establish focus

Integrative Non-Toxic Cancer Treatment at Issels®

Our personalized cancer treatment methods avoid the common side effects that can affect your overall wellness. Contact us for more information.