Tag Archives: Cancer Tumors

New Three-Part Molecule May Decrease Growth of Certain Types of Cancer Tumors

Three-Part Molecule May Decrease Growth of Certain Types of Cancer Tumors
Three-Part Molecule May Decrease Growth of Certain Types of Cancer Tumors

If one is good and two is better, is three the answer? Scientists are hoping that a new three-part molecule could be an answer regarding effective immuno oncology for breast cancer patients.

Stemming the Growth of Breast Cancer Cells

Approximately 20 to 30 percent of breast cancer cases involve over-expression of HER2, which is a growth factor that leads to aggressive multiplication of cancer cells. This acceleration often makes these types of cancer resistant to therapy, resulting in poor prognoses.

Dr. Hongyan Liu, a bioengineer at the Georgia Cancer Center, led a team that developed a chimera, or three-part molecule, to suppress the growth factors. The chimera targets HER2, HER3 and EGFR because one member of the HER “family” can compensate when another one is blocked.

Exploring the Abilities of the Three-Part Molecule

The new molecule is non-toxic, easy to manufacture and relatively cost-effective, making scientists optimistic about its value for immuno oncology. Dr. Liu and her team are currently conducting studies to determine if the chimera can treat cancer that is resistant to Herceptin, a drug that inhibits HER2.

Breast cancer is not the only form that grows due to over-expression of HER receptors. Dr. Liu is hopeful that the chimera will have future applications for lung, head and neck cancers as well.

Issels®: The Leader in Personalized Immuno Oncology Treatments

Our non-toxic immuno oncology programs have been successful in treating therapy-resistant cases of breast cancer and other forms. Contact us today to learn more about how we are carrying on the legacy of our founder, Dr. Josef M. Issels, who predicted the future of immunotherapy.

Personalized Vaccines Are Recognized as the Future for Cancer Treatment

Cancer Vaccines
Cancer Vaccines

Vaccines save lives by utilizing the patient’s immune system to attack harmful cells. Much like flu vaccines prepare the person’s body to defend against pathogens, cancer prevention vaccines are given to people who do not have cancer to help their body identify and destroy infections known to lead to cancer. Treatment vaccines are for people who are already diagnosed with cancer. Issels® Integrative Immuno-Oncology uses non-toxic vaccine and cell therapy that is prepared from the patient’s own blood.

Washington University study

A recent study by scientists at Washington University found personalized cancer treatment was able to cure 90 percent of the mice used in the study that had advanced muscle cancer. This success prompted Alumni Professor of Pathology and Immunology for the university Robert Schreiber, PhD, who was senior author of the study, to say personalized cancer vaccines should be used to treat cancer in humans right away.

Immune-based treatments

Years of research on cancer genetics and how the immune system interacts with cancer have made new vaccines and treatments possible. Scientists agree immunotherapy is the best path to a cancer cure.

A personalized vaccine requires samples from the DNA of the individual’s tumor and healthy tissue. This aspect of creating an effective vaccine is difficult because cancer cells develop from the healthy cells of the person and are not easily recognized as harmful by the immune system. Despite the difficulties, experts agree that this type of integrative strategy is the best path to successfully treating cancer.

To find out more about the cutting edge non-toxic treatments and cell therapies utilized by Issels® Integrative Immuno-Oncology, contact us by phone or via our short online form.

Could Immuno-Oncology Be the Cancer Cure We’ve Been Waiting For?

Immuno-Oncology
Immuno-Oncology

Some cancer researchers are calling immuno-oncology the cure for cancer we’ve all been waiting for. While it seems too early to say we’ve won the war against cancer, what western medicine is calling immuno-oncology and Issels Integrative Oncology Centers call integrative immunotherapy, is clearly a giant step in the right direction. Even conservative members of the cancer community consider advanced immunotherapy to be “the most exciting development in cancer care” and have been impressed with clinical reports of “dramatically extended survival,” according to Canada’s National Post.

How Immunotherapy Fights Cancer

One of many problems with traditional cancer treatments — surgery, chemotherapy, radiation – is that they tear down the body, destroying healthy cells along with cancerous ones. Immunotherapy takes a completely different approach. By tapping into the power of your body’s immune system, immunotherapy works with your body, strengthening your body’s natural defenses and helping immune cells to identify, seek out and destroy cancer cells.

“Mind-Blowing” Results

Cancer cells have a frustrating ability to disguise themselves and hide from immune cells. New targeted therapies use T-cells and Natural Killer Cells to unmask tumor cells and strengthen your immune system’s ability to ferret out and destroy cancer cells. Yale University immunologist David Hafler called the results of such treatments “mind-blowing.”

The use of autohemotherapy has also produced some amazing results in a number of patients battling late-stage cancers. Some patients who were told they only had weeks to live have found new hope as their tumors disappeared after immunotherapy treatment.

Issels has been a leader in integrative immunotherapy treatments for cancer for more than 60 years. Visit our website to learn more.

Unexpected Cancer Tumor Complexity Requires New Treatment Protocols

DNA
Cancer tumors are considerably more genetically complex than thought.

Unlocking the body’s genetic code has led to myriad discoveries that are transforming medicine. One unexpected discovery is that cancer tumors are considerably more genetically complex that previously believed, causing researchers to rethink current traditional methods of treating cancer.

“Until recently, it was assumed cancer cells were more or less identical clones of each other. We have found this is not true. Cells, taken from a single tumor from one person, can have many different genetic alterations within them,” Chris Jones of the Institute of Cancer Research in London told The Guardian.

Mapping of the human genome opened the door to targeted cell therapy. Of the body’s 23,000 genes, scientists found 150 genes with mutations that could trigger cells to create cancerous tumors. Scientists found that the various triggering mechanisms could be targeted and tumor growth slowed or halted using new cancer drugs that redefined chemotherapy. Now instead of a blanket approach that killed healthy cells along with the cancerous ones, specific drugs could be used to target cancer cells without harming healthy cells.

Initially, patient response to these new targeted drug treatments was impressive. However, in many cases cancer returned 6 months after treatment; but this time tumors were drug-resistant. What scientists discovered surprised them. When drugs blocked one path to tumor development, cancer cells demonstrated their genetic complexity by finding a new path.

The problem may be that traditional chemotherapy, even when targeted, is a destructive force designed to tear down the body. Issels personalized integrated immunotherapy, on the other hand, uses targeted cell therapies designed to build up the body’s immune system, strengthening its ability to fight cancer.

To be continued