Category Archives: Alternative Cancer Treatment

Chemotherapy Takes a Back Seat to Immunotherapy for One Patient

Fighting Cancer
Fighting Cancer

Who could testify to the benefits of immunotherapy with more credibility than an actual patient? Philip Pritchard of Memphis was diagnosed with renal cell cancer. Thanks to treatment with immunotherapy drug nivolumab, Pritchard has seen all traces of the disease virtually disappear.

Pritchard’s battle with cancer

Even after undergoing surgery and other treatments, Pritchard’s cancer had metastasized to his liver and lungs. An eight-inch, three-and-a-half pound tumor had been removed from his kidney. Pritchard had only months to live when he came under the care of oncologist Nizar M. Tannir at MD Anderson Cancer Center in Houston.

Implementation of immunotherapy

Pritchard became one of the patients in Tannir’s clinical trial of nivolumab. The first signs came within two weeks, when Pritchard stopped suffering from  the cancer’s side effects like pain, night sweats and anemia. Four infusions over eight weeks led to a 50-60 percent reduction in the size of the main tumor.

That was in early 2013. Today, two years later, 50-year-old Pritchard has regained his health to such an extent that Tannir is considering the end of medication.

How do these immunotherapy drugs work?

Cancer cells have an innate ability to avoid the body’s T-cells, which are sent out by the immune system to attack foreign elements. Nivolumab and the other immunotherapy drugs are “checkpoint inhibitors” that remove the “brakes” keeping T-cells from doing their job.

Our Center for Immuno-Oncology creates a personalized therapy protocol using information about your genetics, lifestyle and environment. We work with patients diagnosed with all types and stages of cancer. Contact us today to learn more about our comprehensive treatment programs.

First Ever Immunotherapy for Cancer Conference Schedule for September 2015

First Ever Conference
First Ever Conference

If you have been uncertain about the future of immuno-oncology, you have merely to look at the sudden increase in research studies and events related to the topic happening around the world. At Issels® Integrated Immuno-Oncology, we remain dedicated to keeping up-to-date with current advances.

This year marks the first conference ever dedicated to discussion about the future of immunotherapy as a survival option for cancer treatment. “The Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival,” sponsored by the Association for Cancer Immunotherapy, the American Association for Cancer Research, the European Academy of Tumor Immunology and the Cancer Research Institute, will be hosted at the Sheraton New York Times Square Hotel in New York City in the United States from September 16th to the 19th. It is being referred to as a point of reference, educational and networking meeting for everyone who is currently working in this area, including patient advocates, doctors, scientists, drug developers and regulators. According to the AACR, the conference is planned as a biennial event. The 2017 event will be hosted somewhere in Europe.

Leaders in cancer immunotherapy science and treatments will be giving over 60 talks about a wide range of topics, including biomarkers, checkpoint blockade inhibitors, combination therapies, genomic methods for identifying tumor antigens, tumor microenvironments, the microbiome, T-cell responsiveness and related therapies.

At Issels®, we are excited that immunotherapy is finally receiving the recognition it deserves as a non-toxic and personalized cancer treatment option. For more information about how this event will help improve your current treatments, or to schedule an appointment for an immunotherapy treatment plan evaluation at one of our Issels® centers, contact us today!

The New Focus on Immunotherapy Drugs for Cancer Treatment

Hypothermia To Fight Cancer?
Focusing On Immunotherapy

No single cure-all cancer immunotherapy drug exists at this time. Instead, modern medicine offers several FDA approved single and combination drug options.

What do they do to the body?

As outlined in the Vox article “Is Cancer Immunotherapy Really a Miracle Cure?,” these treatments prompt a person’s immune system to destroy cancer cells when it will not do so on its own. Immuno-oncology research began as early as the 1890s when Dr. William Coley discovered he could shrink tumors in some patients by injecting bacteria directly into their tumors.

Immuno-oncology was mostly ignored for over a century because of more evident successes in surgical, radiation and chemo therapies. Yet, many researchers now believe it could be the key to curing cancers. Modern technologies have helped us better understand at the cellular level how cancer forms and spreads and how the body responds to different treatments.

Are there risks?

Every treatment available poses risks. Like chemotherapy, immunotherapy drugs have toxic side effects and can even cause adverse immune system reactions. Currently, these immunotherapy drugs do benefit many patients.

  • Their immune systems destroy targeted cancer cells and tumors.
  • They receive remission benefits for months longer than other treatments.
  • Some receive benefits for years longer.

Researchers are only beginning to understand how they can use modified viruses to prompt the immune system to work harder and more efficiently. As the article outlines, their biggest challenge is determining who will benefit and how to create new treatments for everyone else.

If you have exhausted all other options, our personalized Issels immunotherapy with non-toxic vaccine and cell therapies prepared from your own immune cells could turn everything around.

Does the High Cost of Immunotherapy Mean You Won’t Get Treatment?

nurse feeds data of test tubes with blood for analysis into the database
Issels has options for immunotherapy treatment of cancer.

Immunotherapy for cancer that costs more than $1 million per patient per year? Issels® knows how frustrating coming to terms with the affordability of cancer treatment can be, and you’re not the only one taking notice. At the American Society of Clinical Oncology 2015 meeting, Dr. Leonard Saltz, MD of NYC’s Memorial Sloan Kettering Cancer Center brought the stark reality of this issue to light.

Unsustainable
Among the concerns addressed by Dr. Saltz was the need to establish cost controls for treatment, as there is an upper limit to how much society can afford to pay. Prices are not being based on the value of drugs, but what (the seller believes) the market will bear.

The trickle-down…
This year, the cost of a family insurance plan plus out-of-pocket expenses equates to approximately 50% the average U.S. household income. Continue this trend, and by 2028 it will be 100%.

How bad is it?
Saltz identified multiple therapies whose prices were in excess, limiting accessibility. The latest: pembrolizumab (Keytruda):

  • 2mg/kg (2014 standard dose) – $14,500 per month.
  • 10mg/kg (2015 proposed clinical trial dose) – $83,000 per month.

The astronomical out-of-pocket?
Saltz calculated for the average, 165 pound American patient, the drug would cost $1,009,944 per year for 26 doses. With a 20% Medicare copay, that’s a whopping $201,988 out-of-pocket for a single year of treatment! This stark reality is hoped to lead to a drastic changes in melanoma treatment, as many patients cannot afford medical insurance, least of all these copays and therapies.

Has playing the lotto become your backup plan for affording cancer treatment? Don’t give up hope. Contact Issels® and discover an array of cutting-edge immunotherapy  options today!

Researchers Predict a Rise in Breast Cancer

Cancer Detection
Researchers Predict A Rise In Breast Cancer

At Issels® Integrative Immuno-Oncology, we pay close attention to research about cancer trends from around the world to help us improve our precision treatment methods.

According to research results announced in April by Dr. Philip Rosenberg, Ph.D of the National Cancer Institute’s Division of Cancer, Epidemiology and Genetics, Americans will see several new breast cancer trends by 2030.

Age Matters

Longer lifespans will result in more breast cancer cases:

  • Dr. Rosenberg predicts a more than 50 percent rise in breast cancer cases, including an estimated 11 percent increase in older women.
  • Women who live into their 70’s and early 80’s are at a higher risk of getting ER-positive in situ cancer (i.e. tumors caused by estrogen that are confined to the breasts).
  • ER-positive in situ cases will increase overall by an estimated 10 percent.

Hopeful News

Whether you have cancer or not, it’s important to remember the following:

  • These predictions were based on other predictions and assumptions — for example, that mammography will remain a major detection method.
  • The predictions were also based on incomplete and old data, including U.S. Census Bureau data, aggregate details about 500,000 patients diagnosed with cancer in the years up through 2010 and total cancer case numbers from 2011.
  • If the predictions are accurate, at least one group will deal less with certain breast cancers: a 10 percent decrease in overall cases for those ages 50 to 69.
  • Dr. Rosenberg also predicts an 8 percent decrease in the number of ER-negative in situ and invasive cancers that are difficult to treat.

To learn more about this study, cancer trends and/or our treatment options, contact our expert and caring Issels® staff today.

Promising New Treatments Use Molecular Cancer Classifications for Melanoma

Cancer Treatment in Tijuana
Preventing Melanoma

In a groundbreaking effort that could lead to improved strategies even for stage four melanoma treatment, researchers have gathered national data to better determine cancer risk of four major molecular subtypes of cancer. What does this mean for your cancer treatment efforts? Issels® wants you to know.

Improved classification of data = better treatment.
Broken down by age, race/ethnicity, poverty level, and other factors, the data gathered will help researchers more accurately determine the degree of risk, and cancer patients better understand health implications based on their breast cancer subtype, as each of the four major molecular subtypes responds differently to treatment and has varying survival rates.

More access = better treatment.
Also improving strategies for stage four melanoma treatment, the data gathered has been recorded by cancer registries nationwide, making widely available medically important information to guide therapeutic strategies for these cancer subtypes.

Faster identification = better treatment.
The new diagnostic categories identified by researchers will further support the prevention and treatment of multiple types of cancer, as well as monitor their incidence and outcomes, providing further necessary data for the use in stage four melanoma treatment.

Promising findings = a better future for you.
The findings, as well as the statistical analysis of the most common types of cancer, were reported in “The Annual Report to the Nation on the Status of Cancer, 1975-2011,” which also confirmed encouraging trends in cancer mortality among men, women, and children alike, reflecting the progress made over the years in cancer prevention, early detection, and treatment.

Struggling with stage four melanoma treatment? Issels® help you on the path to recovery. Contact us today.