Category Archives: Cancer Research

Could Your Breast Implants Cause Cancer?

Find Out More About Breast Cancer Treatment
Find Out More About Breast Cancer Treatment

Women everywhere are turning to breast implants to improve body image, however a new study suggests there may be an unthinkable risk – a rare type of lymph cancer known as Anaplastic Large Cell Lymphoma (ALCL). How are victims of this phenomena treating their cancer?

ALCL treatment options ALCL cancer victims have been successfully treated with chemotherapy and radiation therapy. The lymphomas were also discovered to disappear on their own following removal of the implants and the surrounding tissue. Subtypes and outcomes include:

• Subtype 1 In this subtype, women with protein positive ALCL, where tumor cells produce an abnormal protein, were said to have better outcomes.

• Subtype 2 In this subtype, protein anaplastic lymphoma kinase (ALK) is not produced by cancer cells.

• Subtype 3 Discovered during the study and requiring further research, the tumors cells in this subtype also do not produce ALK.

How many women have been effected? ALCL has been documented in 71 women who have undergone breast augmentation. The cancer develops several years after surgery, in the scar tissue surrounding the implant.

Why are the implants causing lymphoma? Unfortunately, researchers have been unable to pinpoint the particular reason(s) for the breast implants resulting in cancer. It is theorized, however, that perhaps an abnormal immune response from the body is resulting in the emergence of this cancer.

Digging a little deeper The team that conducted the study, a research team of experts from the Medical University in Vienna, the University of Veterinary Medicine, Vienna and the Ludwig Boltzmann Institute for Cancer Research, are expected to perform further studies to determine the impact of implants and dentures in other parts of the body.

Concerned about the impact implants may be having on your body? If you have developed this type of breast cancer please consider checking with Issels Integrative Oncology today.

New Breast Cancer Medication Causes an Exceptional Response in Test Patients

New Innovative Treatments Are In The News
New Innovative Treatments Are In The News

‘Hope springs eternal’ is a good old-fashioned saying that fits perfectly when discussing a new breast cancer medication that is sparking positive results.

The drug in the news is called, everolimus – brand name Afinitor. It has been approved for two years and used to fight against certain breast cancers and also  treat tumors in the pancreas and kidneys. It is known for creating “exceptional responses” to treatment due to a recent turn of events for patient, Grace Silva, whose story was recently published in the New England Journal of Medicine.

After taking the drug for approximately two months, the 58-year-old experienced her “exceptional response” when tumors in her lungs virtually disappeared. According Dr. Jochen Lorch, Silva’s oncologist, this type of result from drugs is nearly non-existent.

Research studies to understand why exceptional responses occur are on-going. One reason is due to a technology known as next generation sequencing. The once very expensive test to decode DNA genetics in cancer patients is now much more affordable due next-generation technology.

With this genetic technology available, doctors have additional information at hand that helps them determine mutations in tumors, such as Grace Silvas. Mutations can have several effects including increasing the size of a tumor, enabling cancer cells to resist drugs, or working toward shrinking tumors.

Another piece of good new is from the National Cancer Institute that has initiated a new program called the Exceptional Responders Initiative focused on cataloging and identifying mutation patterns. This new initiative along with upgrades by cancer researchers to the way they work with new drugs is jump-starting additional studies. With new visions on the horizon, the future for cancer patients is brighter.

If you are seeking new innovative treatments for your cancer, we invite you to evaluate the Issels Treatment programs.

2014 Breast Cancer Findings of Special Note

Newspaper
Cancer Findings of Note in the News

Cancer can strike any of us at any age and leave us feeling helpless and uncertain of what to do in response. Issels Integrative Immuno-Oncology has been successfully treating cancer patients with individualized therapy since 1951. The Issels Foundation researches holistic treatment and educates people about their options for combating cancer. This has been a significant year for breast cancer research. New information published can help every woman.

Diabetes is linked to breast tumor size

The Huffington Post reports that high levels of insulin in the blood stream may stimulate growth of tumor cells. This is according to Dr. Caterina Fontanella, MD, who says, “We therefore believe that strict control of blood sugar levels is essential to the successful treatment of breast cancer.”

One skirt size increases breast cancer risk

We know obesity increases everyone’s risk of developing cardiovascular disease. A recent study published in the British Medical Journal finds a person who increases one skirt size every 10 years has a 33 percent higher risk of developing breast cancer.

Some birth control pills likely increase risk

Women taking pills containing high levels of estrogen may have a 50 percent higher risk of developing breast cancer than women who have never taken oral contraceptives, according to a recent study. The increased risk declines when they stop taking these birth control pills.

Lifestyle changes reduce breast cancer risk for all

According to two studies by the Yale Cancer Center, breast cancer survivors who eat a healthy diet and get regular exercise reduce the chance of cancer coming back and increase their likelihood of survival.

Visit our website for the latest developments in cancer research.

Nanoparticles: Attacking Cancer from All Angles

Attacking Cancer From All Sides
Attacking Cancer From All Sides

The second leading cause of death in the U.S., the fight against cancer needs all the weapons in its arsenal that it can get. Step-in nanoparticles, tiny but tough tools ready for battle in the war.

An enormous job for infinitesimal workers: Nanotechnology in early cancer detection
Targeted delivery of specific nanoparticles to a tumor site can induce a reaction with cancer cells, prompting the body to significantly increase the production of biomarkers necessary for cancer identification. Earlier detection and diagnosis allow less burdensome treatments, offers a faster diagnosis than biopsies, and increases chances of recovery.

Miniature mappers: Nanoparticles in imaging
Nanoparticles engineered with magnetic properties are effective imaging agents when used with MRI scans. Nanites bind particularly well with tumors, allowing a very high resolution, clear map of cancerous sites for the planning of surgical removal or treatment.

Small but mighty: Nanites in cancer therapy and drug delivery
A revolutionary new technology in the fight against cancer, nanoparticles are capable of a variety of attacks against this deadly disease. Nanites can be injected into a tumor to produce heat, allowing for the destruction of cancer cells locally with X-rays, magnetic fields, or light; They can be used to encapsulate chemotherapy drugs or genes for localized delivery and a significant reduction in quantity of drugs as well as a reduction in side effects and impact on healthy tissue; and more, including an array of up-and-coming technology (LINK TO GOOGLE ARTICLE) currently under development.

Don’t stand on the sidelines in the fight against cancer. Learn more about how technology at Issels Integrative Oncology can help you today.

New Google Tech Aims to Diagnose Cancer

The Latest In Cancer Treatment
The Latest In Cancer Treatment

Since early diagnosis is key to treating cancer and other diseases, mega-corp Google is working on developing technology that will aid in the early diagnosis of cancer, heart attacks, strokes, and other diseases, much earlier than is currently possible.

Breakthroughs in nano-technology are hoped to lead the way
Google’s plan is to combine disease-detecting nanoparticles, swallowed via pill, with a wristband that will perform non-invasive blood tests. The goal is for the nanoparticles to identify and match markers for different conditions, then travel back to the wristband to communicate these slight changes in a person’s biochemistry that indicate the early symptoms of disease.

A step ahead
Cancerous and healthy tissues are decidedly distinct, and if Google’s technology is able to identify the unique traces of these unhealthy tissues in the blood before physical symptoms appear, diagnosis can be made when cancer is still preventable or treatable.

Technology dream-team
The product will be developed by the search company’s semi-secret innovation lab, Google X, and led by Dr. Andrew Conrad, molecular biologist and inventor of a now widely used inexpensive HIV test.

Preventing false-positives
Because of the increase in anxiety the identification of these markers could create, Dr. Conrad has emphasized the need for rigorous testing before the product’s release and widespread use to prevent unnecessary worry – or unnecessary treatment. Once released, however, this technology is expected to be a revolutionary and effective weapon in the prevention and treatment of cancer.

Looking for ways to become proactive with your cancer treatment plan? Contact Issels Integrative Oncology today.

Cancer Drugs in the News

New Cancer Drugs
New Cancer Drugs

There’s so much negative news bombarding TV, newspaper, Internet, and radio, every day, that sometimes it can become overwhelming. On the plus side, when positive cancer news is forthcoming, we don’t want to miss it.

A recent conference in Madrid covering new cancer drug information brought exciting news and results to the forefront regarding immunotherapies and the effects on the immune system of cancer patients when combined with approved drugs.

Merck & Co., Bristol-Myers Squibb Co., Roche Holding Ltd. and AstraZeneca each offered data compiled from initial testing. While results were positive from each company, there still exists a concern due to toxicity leading to negative side effects when immunotherapies are combined.

Immunotherapy drugs act on a specific protein known as Programmed Death Receptor 1 or PD-1 or PD-L1. Two of these drugs have received the stamp of approval. One drug, Keytruda from Merck, was approved in the U.S. The other, Opdivo from Bristol-Myers, was approved in Japan but not yet in the U.S.

Clinical date from AstraZeneca’s PD-L1 shows promise against lung cancer. Roche shared its results using its immunotherapy drug combined with an additional drug, Avastin, a non-immunotherapy drug used against breast cancer.

While the news is good and results have been positive showing increases in patient responding to treatment ranging from 22 percent to 40 percent, there can be side effects. The lowest result was at 8 percent for colorectal cancer patients.

Safety remains a priority with immunotherapy combinations but each company plans to continue its clinical trials with patients across the board dealing with pancreatic, neck, head, gastric, and ovarian cancer and melanoma.

At the end of the day, it’s good news.