Tag Archives: Genetics

Cancer News Roundup for July

The Latest In Cancer Treatment
The Latest In Cancer Treatment

The latest in cancer treatment news for July:

  • Rogue cancer cells in blood could help explain how tumors evolve as genes change over time, leading to new cancer treatments.
  • Study finds faulty process in muscle-invasive bladder cancer, pointing to EGRF targeting drugs as possible cancer treatment.
  • The National Cancer Research Institute points to the need for age limits in clinical trials to be more flexible to allow teenage cancer patients greater access to new treatments.
  • Genetic research identifies three rare pathogenic mutations not previously known in public gene sequencing databases known to predispose carriers to breast and Lynch syndrome spectrum cancers.
  • A new research report shows antihistamines used to treat colds, allergies and insect bites may play a role in warding off tumors.
  • Study shows men over 50 who cycle more than nine hours a week are more likely to develop prostate cancer.

Looking for more information on cancer treatment specific to yourself or a loved one? Contact Issels today. Issels offers the latest and most effective alternative cancer therapies available.

Blood Samples Being Used to Personalize Breast Cancer Treatment

Alternative Cancer Treatment
Alternative Cancer Treatment

Boston scientists are attempting to use blood samples to personalize breast cancer treatment for women with rare forms of the disease. After filtering tumor cells from patient blood samples, researchers have been studying how the cells grow and begun to experiment with possible solutions for halting cell growth. The new technique has the potential to allow “real time monitoring” of tumor changes and usher in a new era of individually designed cancer treatments.

“Tumors change, and from the time that a woman is diagnosed with metastatic breast cancer that needs to be treated to the time that multiple treatments have worked and stop working, the tumors have evolved,” Dr. Daniel Haber of Massachusetts General Hospital Cancer Center recently told the Boston Globe.

Real Time Monitoring

The new technique would allow oncologists to monitor tumor development and treatment resistance in real time and make treatment adjustments more quickly, hopefully preventing the spread of cancer and hastening the administration of more effective targeted therapies. The ability to track such changes through blood tests could also spare breast cancer patients the trauma of multiple invasive biopsies.

When Cancer Cells Circulate

The circulation of cancer cells in the blood stream is considered a strong indicator that cancer is spreading beyond the original tumor site. Cancer cell circulation is also believed to be a primary mechanism for metastasis. The ability to track the real time emergence of cancer cell mutations through blood samples is still a work in progress. While intriguing, researchers were only able to culture cancer cells in one-sixth of the blood samples.

Visit our website to learn about Issels personalized treatment programs for breast and other cancers.

Quality of Life Benefits Drive Mainstream Adoption of Alternative Cancer Treatments

Acupuncture
Acupuncture

In what many consider to be a revolutionary change in traditional medical thinking, alternative cancer treatments are going mainstream. With a growing number of studies and mounting clinical evidence pointing to the quality of life benefits of many alternative treatments, practitioners of Western medicine have begun adopting alternative cancer therapies.

“Rebirth” of Alternative Cancer Therapies

Once given short shrift by traditional oncologists, acupuncture, autohemotherapy, massage therapy, hyperthermia, phytotherapy and a lengthy list of beneficial alternative cancer therapies are undergoing “rebirth” as the traditional cancer community recognizes their quality of life benefits in the light of new research revealing the importance of immunotherapy in fighting cancer.

Alternative treatments are not new, but have been used to battle disease or ease its symptoms for thousands of years, as these examples indicate:

  • Acupuncture has been an accepted and respected treatment procedure in traditional Chinese medicine since ancient times.
  •  The use of herbal medicine, or phytotherapy, dates back to man’s earliest attempts to treat disease and has historical significance in nearly every human culture.
  •  The therapeutic use of massage therapy also has its roots in antiquity. The Greek physician Hippocrates, considered to be the Father of Medicine, wrote about the therapeutic benefits of “rubbing” in the 5th century B.C.

Everything Old Is New Again

What is “new” in Western medical circles is recognition of the validity of these ancient therapies and their ability to enhance cancer treatment and mitigate the pain and side effects of traditional cancer treatments.

For more than 60 years, Issels Integrative Oncology has incorporated beneficial alternative cancer therapies into our personalized immunobiologic core treatment for cancer as part of our comprehensive program of integrative immunotherapy.

Can Fasting Boost Your Immune System?

Fasting To Build The Immune System
Fasting To Build The Immune System

A new study by University of Southern California researchers suggests that a three-day fast may jump-start the body’s immune system by triggering the production of new white blood cells. USC scientists believe that medically monitored fasting could help cancer patients, the elderly and others with damaged immune systems regenerate healthy immune systems. If initial results are upheld, the discovery could add a potent tool to the practice of integrative immunotherapy and the non-toxic treatment of cancer.

Regenerating White Blood Cells

Your immune system is your body’s natural line of defense against disease and white blood cells form its front lines. In USC patient trials, prolonged fasting forced the breakdown of white blood cells, especially damaged cells, which triggered stem cell regeneration of healthy new white blood cells.

Cancer places serious strain on the immune system. Some cancer treatments, particularly chemotherapy, can seriously damage your immune system, leaving you with little natural defense against cancer. If medically monitored fasting is proven to regenerate the immune system, it could be a game-changer in the treatment of cancer.

Supercharging Your Immune System

Integrative immunotherapy has already been shown to improve quality of life both during and after cancer treatment. By tapping the power of your body’s immune system and enhancing the ability of immune cells to target cancerous tumors and the tumor microenvironments that affect the growth and spread of cancer, integrative immunotherapy works with your body to defeat cancer naturally without harming surrounding healthy tissue. By aiding regeneration of the immune system, it might be possible for fasting therapy to “supercharge” your immune system’s ability to fight cancer.

Please visit our website for more information on integrative immunotherapy.

New Lymphoma Treatment Appears Promising

Lymphoma Treatment
Lymphoma Treatment

Medical researchers continue to make strides in the battle to control cancer. A Seattle-based biotech company has developed a drug that is showing promise for treatment of lymphoma, a form of cancer that attacks the body’s immune system.

Gilead Sciences has been testing an oral drug called idelalisib. It works to inhibit development of P13K deltas, a group of enzymes commonly found in B-cell malignancies, which make up the majority of non-Hodgkin lymphoma cases. A recent study was conducted through the Clinical Research Division of Fred Hutchinson Cancer Research Center, also located in Seattle.

The focus group was comprised of 125 patients between the ages of 33 and 87 who were diagnosed with indolent non-Hodgkin lymphoma. This particular form, also known as slow-growing, is difficult to treat as the disease often becomes resistant to therapy. After receiving twice-daily doses of idelalisib, 57 percent of the patients saw their tumors shrink by at least half while six percent showed no measurable evidence of cancer.

According to Ajay Gopal, M.D., lead researcher in the study, the patients had exhausted all current means of therapy and several had relapsed. One of the more encouraging results was the relative lack of side effects, unlike chemotherapy treatments. The most common side effects were diarrhea and colitis, which were successfully managed by adjusting the dosage. While it doesn’t appear that idelalisib is a cure, researchers are hopeful that it will be a valuable treatment for controlling lymphoma for extended periods.

Our alternative cancer treatment center uses programs of non-toxic immunotherapy tailored to your individual needs. Many of our patients have achieved long-term remission of lymphoma and other forms. Please visit our website for more information.

Advances in Genetics Boost Success of New Immunotherapy for Cancer

Advances In Genetics
Advances In Genetics

Thanks to the advancement of gene sequencing techniques such as high-throughput genome sequencing, capable of breaking down an entire genome in a single day, a new cancer cell therapy treatment may become available to patients.

Successfully used to treat Melinda Bachini, a 45 year old Montana woman suffering from a rare bile-duct cancer after standard chemotherapy failed and resulted in hair loss and nerve damage, Bachini researched and decided to try the new experimental cancer therapy.

Reported in the journal Science, Dr. Steven Rosenberg’s team at the National Cancer Institute used a combination of cutting-edge genomics and recent insights into the human immune system. They identified specific CD4 T-cells  attacking the cancer in Bachini’s body, then literally pulled them off the tumor they were attacking and grew them in lab to later re-infuse into Bachini.

Treating Bachini first with strong chemotherapy to kill competing immune cells, she then underwent 2 rounds of this new treatment. The first reduced symptoms immediately and proceeded to shrink the tumors over 6 months. A second became necessary when the tumors began to grow back. All the mutations present in the cancer – and their associated T-Cells – had to be isolated, grown, and re-infused in order to eradicate the tumors.

This new immunotherapy for cancer is hoped to be used as a blueprint for attacking other types of cancers. Bachini’s case was the first to be treated with this personalized approach and also the first time doctors have been able to target a specific mutation in the immune system. It is anticipated further research into this alternative cancer therapy will provide additional treatment options for a wide array of cancers in the not-too-distant future.