Category Archives: Alternative Cancer Treatment

NCI Studies Disparities in Cancer Treatment in Rural Communities

If You and Your Family Does Choose to Live Out in the Country, Make Sure You Live Close to a Location with Good Healthcare Providers.
If You and Your Family Does Choose to Live Out in the Country, Make Sure You Live Close to a Location with Good Healthcare Providers.

Does where you live affect your chances of surviving cancer? Recent studies are putting a focus on the disparities of cancer treatment between rural and urban communities.

Equal Access to Health Care?

Overall, cancer death rates in the United States have declined over the last 40 years. Unfortunately, two studies from the National Cancer Institute and Centers for Disease Control have revealed that cancer death rates are higher in rural areas and declining at a much slower pace.

NCI has a history of promoting cancer control in Appalachia, with efforts directed at prevention and early detection. Issues surrounding last year’s presidential election have further raised the visibility of questions about access to quality health care.

As research methods and tools become more sophisticated, scientists have the advantage of more granular data. This allows for more detailed plotting of disease patterns and trends as they apply to specific geographic regions.

Healthcare Organizations Rise to the Challenge

Growing acknowledgement of the problem is also raising the sense of urgency. Researchers at the University of Washington found that differences in life expectancy by county are large and growing even larger.

NCI, along with federal agencies such as the Centers for Medicare and Medicaid Services, are joining forces to collaborate on research and implementation. The next big step is a May 2018 meeting that NCI is convening among major organizations in the cancer community.

Issels®: Accessible and High-Quality Cancer Treatment

Our integrative immunotherapy programs incorporate multiple elements to create the best possible treatment for your particular diagnosis. Contact us for more information about cancer vaccines, NK cells and other non-toxic treatment methods.

Multiple Myeloma Patients React Positively to CAR T Cells Treatment

New Discoveries for Making Cancer Easier to Bear Are Sprouting Up!
New Discoveries for Making Cancer Easier to Bear Are Sprouting Up!

CAR T cells, engineered from a patient’s own immune cells, have proved to be a valuable weapon in immunotherapy cancer treatment. Now, recent trials demonstrate that CAR T cells may be effective against advanced multiple myeloma.

Global Testing of CAR T Cells

Earlier this year, two groups performed tests on CAR T cells designed to target B-cell maturation antigen (BCMA), a protein specific to myeloma.

  • Researchers in China conducted a study in which 33 of 35 patients went into complete remission within two months of treatment.
  • A team in Tennessee administered different doses of the CAR T cells to 21 patients. Beyond the first-level dose, patients experienced a 100 percent response rate, with 27 percent achieving a stringent complete response indicating no presence of the disease.

In another encouraging result, patients in both trials who experienced side effects were able to be successfully treated.

How CAR T Cells Fight Cancer

Unlike more traditional forms of cancer treatment, CAR T cells fall under the umbrella of immunotherapy. A patient’s individual immune cells are harvested from their blood, then engineered to target antigens, which are foreign bodies that trigger an immune response.

The CAR T cells are multiplied until they reach a quantity in the billions, then reintroduced into the patient. According to Dr. James Kochenderfer, lead author of the U.S. study, the key is targeting antigens that aren’t expressed in healthy tissues.

Immunotherapy at Issels®: State-of-the-Art Cancer Treatment

For decades, Issels® has been a leader in the healthcare community with our non-toxic, personally-tailored immunotherapy programs. Visit our website to hear success stories from patients with all forms of cancer.

Gold Nano Particles May Boost Lung Cancer Treatment

Gold Nano-particles Can be Introduced into the Bloodstream to Help Fight Cancer.
Gold Nano-particles Can be Introduced into the Bloodstream to Help Fight Cancer.

Gold may have a value that goes well beyond financial gain. Researchers have discovered that the shiny element can enhance the effectiveness of drugs used to treat lung cancer.

Cancer Treatment as Good as Gold

Testing was conducted at the University of Edinburgh, where Scientists took nanoparticles, which are microscopic particles of gold, and encased them in a chemical device. The object was then used on zebrafish to successfully accelerate their chemical reactions.

Dr. Asier Unciti-Broceta from Cancer Research U.K.’s Edinburgh center participated in the study. He explained that the team’s goal was to find a way to reduce side effects of current chemotherapy methods.

Lessening the Side Effects of Traditional Cancer Treatment

Side effects of cancer treatment are usually the result of drugs attacking healthy cells as well as diseased ones. According to Dr. Unciti-Broceta, their findings indicate that gold could possibly be used to safely release drugs inside tumors.

Immunotherapy for cancer is effective because it helps the immune system’s ability to target cancer cells while sparing healthy tissue. Researchers are continuing tests with nanoparticles in the hopes of applying a similar method with humans.

Dr. Aine McCarthy, also of Cancer Research U.K., expressed optimism that incorporating gold in immunotherapy for cancer could improve the outlook for hard-to-treat cancers such as brain tumors.

Issels®: The Gold Standard of Immunotherapy for Cancer

Our integrative cancer treatment programs are personally tailored for each patient to include methods that complement each other for maximum effectiveness. Contact us today to learn more about our distinguished history of treating patients with all forms of cancer.

New Cancer Treatment Targets Protein Found in Tumors

Links to Cancer are Being Identified Everyday! There is Hope.
Links to Cancer are Being Identified Everyday! There is Hope.

Immunotherapy continues to be a major focus in cancer treatment research. Scientists in the United Kingdom recently began early-phase clinical trials of an experimental drug that targets a protein found in many solid tumors.

Using the Immune System to Attack Cancer Cells

Cancer Research UK and Biotecnol Limited are collaborating on development of a first-in-class Fdrug known as Tb535H. Arising from Trisoma®, Biotecnol’s antibody development platform, the drug targets the 5T4/WAIF1 antigen that is believed to contribute to the spread of cancer cells.

As with most immunotherapy treatments, Tb535H works by harnessing the immune system’s T cells and directing them to attack and kill cancer cells. Biotecnol has been instrumental in partnering with top cancer institutions to develop promising immune-oncology therapies.

Targeted Cancer Treatment

The discovery of the WAIF1 antigen also occurred as a result of studies at Cancer Research UK’s Manchester Institute. While it may ultimately be a target for a number of cancer types, current testing will be limited to cancers with low survival rates, including mesothelioma and small-cell lung carcinoma.

Dr. Nigel Blackburn, director of drug development for Cancer Research UK, acknowledged that the partnership with Biotecnol will accelerate the path of bringing Tb535H to cancer patients. Blackburn also stressed the need for more effective treatment for lung cancer, the cause of 20 percent of cancer deaths in the UK.

Issels® Offers State-of-the-Art Immunotherapy Programs

While immunotherapy is a hot buzzword in cancer treatment today, we have been using non-toxic integrative programs for decades. Contact us to read and hear testimonials from patients with all forms of cancer who have received successful treatment at Issels®.

Tumor Heterogeneity: Why Some Tumors Metastasize or are Drug Resistant

Each Body Is Unique, and So Is Curing Each Cancerous Tumor.
Each Body Is Unique, and So Is Curing Each Cancerous Tumor.

For decades, scientists have tried to uncover the mysteries behind the complex behaviors of cancer cells. Thanks to gene sequencing and other molecular diagnosis tools, they are beginning to understand the process behind metastasis and drug resistance.

Solving the Puzzles of Metastasis and Drug Resistance

Cancer treatment is sometimes hampered by two significant problems:

Metastasis, or stage IV cancer, occurs when cancer cells migrate from the original site to other parts of the body. Surgery is no longer an option at stage IV, which significantly reduces survival rates.

• Drug resistance sets in when treatment reaches a point where cancer cells are no longer vulnerable to attack and they resume spreading.

Scientists have discovered that cancer cells can vary greatly between the original site and metastatic site, and even within a single tumor. This characteristic is referred to as tumor heterogeneity.

How Does Tumor Heterogeneity Affect Cancer Treatment?

Research has uncovered significant evidence demonstrating that cancer cells continue to evolve.

Gene mutations can create a subset of cancer cells with the ability to break away from the original tumor site.

• Drugs that target specific cancer cells can lose effectiveness as the original mutations are lost.

Doctors are using this knowledge of tumor heterogeneity to prescribe combination therapies that attack multiple genetic and molecular targets.

Issels®: A Pioneer in Combination Therapies

Our individual immunotherapy programs are integrative, combining treatments that work together to form a comprehensive attack on cancer cells. Contact us to learn why Issels® is the right choice for powerful and non-toxic cancer treatment for patients in late and early stages.

New Biomarker May Predict the Body’s Response to Chemotherapy and Radiation

There is New Hope for Cancer Patients. Don't Give up!
There is New Hope for Cancer Patients. Don’t Give up!

One of the difficulties doctors have in prescribing cancer treatment is knowing which methods will be most effective. That may change with the discovery of a biomarker that may help predict a tumor’s response to chemotherapy and radiation.

How Cell Division Affects Cancer Development

When cells divide, the duplicated chromosomes are pulled apart into the two new cells. A malfunction in this process can lead to chromosomal instability, which has the potential to drive development of cancer cells.

Researchers set out to study the expression of genes associated with normal chromosome division. Specifically, they wanted to find out how genetic changes contribute to chromosomal instability and whether these changes held clues regarding the behavior of tumors.

Genetic Markers of Chromosomal Instability

The team from Lawrence Berkeley National Laboratory examined 31 genes that had previously been identified as part of the chromosome division process. They discovered that these genes were over- or under-expressed in different types of cancer as opposed to corresponding normal tissue samples.

This led to the development of a 14-gene subset named the Centromere and kinetochore gene Expression Score, or CES. When measuring CES in tumor sample databases, the researchers found that a high score correlated with elevated levels of chromosomal instability.

Based on these encouraging results, researchers are hopeful that the biomarker can be used to predict response to cancer treatment as well as prognosis with or without treatment.

Immunotherapy: An Integrative Approach to Cancer Treatment

Immunotherapy at Issels® doesn’t carry the risk of debilitating side effects that accompanies traditional cancer treatments. Contact us for more information.