Alternative Cancer Treatment, Immunotherapy, Immunotherapy for Cancer

Major Growth in Immunotherapy for Cancer Expected Before 2020

Immunotherapy is Growing!
Immunotherapy is Growing!

Have you been noticing the topic of cancer immunotherapy in news and advertisements? Expect to see it more often in the near future as experts predict a significant increase in the market by the year 2020.

What Is Immunotherapy?

Immunotherapy is the general term for treating disease by affecting the immune system. Suppression immunotherapy restrains the immune system as opposed to cancer immunotherapy, which focuses on activating the immune response.

The immune system is the network that keeps your body safe from viruses, bacteria and other disease-causing organisms. When a foreign substance enters your system, it triggers an immune response to eliminate the threat.

Many types of cancer cells have the ability to slide “under the radar” and avoid detection by immune cells, giving them the opportunity to multiply and travel to other parts of the body. Immunotherapy works to remove the “shield” around cancer cells and help the immune system do its job.

Why Has Immunotherapy Become So Important?

  • Cancer immunotherapy treatments are created to specifically target cancer cells, so they have been useful against increasingly diverse forms of cancer.
  • Immunotherapy has fewer side effects than traditional treatments such as chemotherapy and radiation.
  • Many immunotherapy treatments have proved to be successful, encouraging continued research and development.

Issels®: An Integrative Approach to Cancer Treatment

For more than 50 years, Issels® has been a leader in the development and use of innovative immunotherapy programs. No two cases of cancer are the same, and we use comprehensive testing to formulate personalized treatments. Visit our website for more information about our non-toxic therapies.

Alternative Cancer Treatment, Cancer Research, Immunotherapy

Nanodiscs May Personalize Immunotherapy for Cancer in the Near Future

Training Your Immune System to Fight Off Cancer For You!
Training Your Immune System to Fight Off Cancer For You!

One of the highlights of immunotherapy for cancer is that the protocols are personally tailored to address your individual needs. A research team at the University of Michigan recently developed a way to customize cancer vaccines that holds promise for both current treatment and long-term immunity.

“Training” the Immune System

Immunotherapy for cancer focuses on helping your own immune system battle cancer cells. The vaccine created by the University of Michigan team uses synthetic high-density lipoproteins called nanodiscs to train the immune system to recognize and attack cancer cells.

Nanodiscs use patient-specific genetic mutations, or tumor neoantigens, to trigger production of T-cells by the immune system. The T-cells then use the genetic material in the nanodiscs to target the cancer cells.

The study involved treating mice suffering from melanoma and colon cancer with a combination of checkpoint inhibitors and the nanodisc vaccine. Not only were most of the tumors eliminated, the mice remained tumor-free after the same cancer cells were reintroduced into their systems after 70 days.

University of Michigan Goes All-In on Nanodisc Research

Encouraged by the results of the test, the University of Michigan has created a biotech company named EVOQ Therapeutics to concentrate on developing and refining the nanodisc vaccine. Plans are to conduct further studies on animals before moving into clinical trials.

Issels®: Blazing the Immunotherapy for Cancer Trail

Cancer vaccines are just one of the innovative non-toxic treatments we employ at Issels®. Visit our website to learn more about our specialized testing methods and individualized integrative programs.

Alternative Cancer Treatment, Cancer Research, Immunotherapy, Immunotherapy for Cancer

Medical University of South Carolina’s Antibody Treatment Research Holds Promise

Immunotherapy for Cancer
Immunotherapy for Cancer using Antibody Treatment

Researchers continue to make strides in discovering new cancer immunotherapy methods that help doctors successfully target tumor cells. As revealed in a recently published report, a team of scientists at the Medical University of South Carolina (MUSC) have created a promising antibody-based therapy using a specific diagnostic marker known as GARP.

When Immune Cells Fail

Numerous studies have focused on TGF-beta, which is a protein used by regulatory T-cells (Tregs) to direct immune cells away from healthy cells. Malignant tumors get around this by releasing vast amounts of TGF-beta, essentially hijacking Tregs and causing them to suppress immune cell activity against the cancer cells.

GARP is the only known receptor that lets TGF-beta dock on cell surfaces. The MUSC team set out to determine whether GARP was the means by which tumor cells were able to harness TGF-beta.

Is GARP the Key to Activating Tregs?

After finding that GARP levels were higher in certain types of tumors, the team conducted a test in which they removed the GARP gene from mice with mammary tumors. As a result, the tumors grew more slowly and there was little metastasis to the lungs.

The MUSC team then used human GARP in mice to develop antibodies. Their hope is that in the future, cancer immunotherapy in conjunction with GARP antibodies will result in more effective treatment for breast cancer.

State-of-the-Art Cancer Immunotherapy at Issels®

For decades, Issels® has been the leader in non-toxic integrative cancer treatments that boost your own immune system’s ability to fight tumors. Contact us today to learn more about the Issels® difference.

 

Alternative Cancer Treatment, Breast Cancer, Cancer Research, Immunotherapy, Living with Cancer

Breast Cancer – It’s Not a Cancer that Affects Only Women

Men Are More Likely to Get Bladder Cancer Than Women... Are You at Risk?
Not Only Women are Affected by Breast Cancer

While breast cancer is thought of primarily as a women’s disease, men are not immune. Researchers have recently identified a specific gene mutation that increases the risk of breast cancer in men.

Identifying Genetic Triggers in Male Breast Cancer

There have been a number of studies involving women and inherited BRCA (breast cancer) gene mutations. In a two-year study that was published in 2016, a joint research team from the Anthropological Survey of India and the University of Calcutta conducted a study into genetic factors behind male breast cancer.

The researchers began by collecting blood and tissue samples from several men who had been diagnosed with breast cancer. These samples were then used for gene sequencing to identify mutations that could be causing the disease.

As a result, the scientists were able to identify mutations in the BRCA2 gene that triggered the cancer growth. In addition, the study found that lifestyle and reproductive factors such as hormonal therapy and alcohol consumption can also increase risk.

Differences between Male and Female Breast Cancer

  • The lumps (or primaries) associated with breast cancer are generally smaller in men than in women, making early detection difficult.
  • BRCA2 mutation carriers are found in lymph nodes, so men don’t experience the pain that would make them seek medical care.

Genomic Testing Personalizes Immunotherapy for Cancer

Each patient is different, so immunotherapy for cancer at Issels® uses genomic and other specialized testing to create the optimum course of treatment. Contact us today to learn more about our non-toxic integrative programs such as cancer vaccines and NK cells.

Alternative Cancer Treatment, Breast Cancer, Immunotherapy, Living with Cancer

Actress Uses Cancer Diagnosis to Change Her Life

Targeted Cancer Therapy Can Bring Patients New Hope!
Hope with Diagnosis

Actress Shannen Doherty is best known as one-half of the Walsh twins on the hit TV show “Beverly Hills 90210,” but lately acting has taken a back seat to a more serious challenge. For the past eighteen months Doherty has used social media to share her brave and inspiring battle against breast cancer.

Her Courageous Journey toward Restored Health

In March 2015, then 43-year-old Doherty was diagnosed with breast cancer, which she made public the following August. She filed a lawsuit against her former business managers alleging that the diagnosis was delayed because they left her without medical insurance. The suit was settled this past August.

Early in 2016, doctors discovered that the cancer had spread to Doherty’s lymph nodes, causing her to undergo a single mastectomy in May. When Doherty was presented with the American Cancer Society’s Courage Award at a gala in November, she revealed that she had completed chemotherapy and was beginning a course of radiotherapy.

How Cancer Changed Her Lifemastectomymastectomy

Over the last year-and-a-half, Doherty has documented her treatment online in words and pictures. She credits cancer with making her a “better human being” and demonstrating which people in her life could be truly counted on, a group that includes her mother, husband and friends such as fellow actress Sarah Michelle Gellar.

Immunotherapy for Cancer: A Personalized Path of Treatment

At Issels®, our integrative immunotherapy for cancer programs are designed to address you particular needs. Our protocols attack and kill cancer cells while boosting your body’s own natural defenses. Contact us today for more information.

Alternative Cancer Treatment, Breast Cancer, Cancer Research, Immunotherapy for Cancer

Blocking Cystine May Starve a Hard to Treat Breast Cancer

A Unique Perspective
Block Cancer

Cancer cells have a high-powered metabolism that demands a steady stream of nutrients for fuel. Scientists may have discovered a way to “starve” a hard-to-treat form of breast cancer by depriving the cells of a crucial substance.

Feed a Cold, Starve Cancer?

Triple negative breast cancer (TNBC) is a particularly aggressive and treatment-resistant form. In a study performed at Duke University, researchers found that the cells have an “addiction” to a nutrient called cystine, and deprivation causes them to die off quickly.

Further examination showed that the addiction is triggered by a mechanism used by the cells to migrate to other parts of the body, a process known as metastasis. According to Jen-Tsan Ashley Chi, associate professor at Duke University School of Medicine and lead author of the study, the metastasized cells are the primary target of treatment.

What’s Next?

Chi’s group had previously published a study showing that the cells in a stubborn form of kidney cancer are also subject to the cystine addiction. The next step is to test cystine-blocking molecules on tumors and look for biomarkers that will signal cancer cells that are receptive to the treatment.

As Chi explains, tumor cells use this programming to move rapidly around the body. The researchers’ goal is to take advantage of the same process for a cure.

State-of-the-Art Immunotherapy for Cancer at Issels®

Our personally-tailored immunotherapy for cancer treatments are developed using genome testing and other cutting edge methods. Contact us for testimonials from patients who have been successfully treated for all forms of cancer, ranging from lung cancer to melanoma to leukemia.

Individualized Cancer Treatment