Tag Archives: Cancer Vaccine

Use Your Body to Fight Cancer

Conventional cancer treatment, such as chemotherapy and radiation, focuses on using external methods of destroying cancer cells. Immunotherapy focuses on using your body’s own defenses to fight cancer. Issels® Immunotherapy offers several cancer vaccines that are non-toxic and do not cause adverse effects, including the following.

Prostate Cancer Vaccine

This cancer vaccine helps the immune system find and destroy cancerous cells in the prostate. Prostate cancer vaccines contain monocytes, cytokines, and other elements of the patient’s immune system, which helps provide a more targeted immune response.

Autologous Dendritic Cell Cancer Vaccine

This cancer vaccine involves the use of dendritic cells, which play an important role in the immune system. These cells have a strong potential to trigger an immune response that effectively destroys tumors. This cancer vaccine contains tumor antigens, cytokines, and other elements of the patient’s immune system.

Coley’s Mixed Bacterial Vaccine

This cancer vaccine helps the patient’s body produce interleukins, interferons, and other parts of the immune system that are needed to fight disease.

Lymphokine-Activated Killer Cells

This cancer vaccine contains LAK cells and interleukin-2 that help the patient’s body fight cancer.

Activated Natural Killer Cells

This cancer vaccine contains NK cells and interleukin-2 to help the immune system fight cancer.

Uses for Cancer Vaccines

Cancer vaccines can be used for a wide range of cancer types, including cancers that are typically difficult to treat using conventional methods. Since they use the patient’s immune system to fight cancer, they don’t come with a risk of side effects or adverse reactions as other cancer treatments do. Cancer vaccines are an important part of immunotherapy and provide a highly personalized approach to fighting cancer.

To learn more about immunotherapy as cancer treatment, please contact Issels®. We can give you more detailed information on cancer vaccines and other therapies.

Huntington’s Disease Produced Molecules Are Fatal to Cancer Cells

Huntington's Disease Produced Molecules Are Fatal to Cancer Cells
Huntington’s Disease Produced Molecules Are Fatal to Cancer Cells

Could a clue to more effective cancer treatment be found in the biochemistry of another illness? Scientists are hopeful that the gene behind Huntington’s disease could be fatal to cancer cells without harming healthy ones.

What Is Huntington’s Disease?

Huntington’s disease is a genetically inherited condition that destroys nerve cells in the brain. There is currently treatment but no cure for the disorder, which causes a slowly progressive decline in both cognitive and physical abilities.

The faulty gene that triggers Huntington’s disease contains an excessive number of repeats of a certain sequence of nucleotides, which form the building blocks of DNA and RNA. These sequences create small interfering RNAs, which are molecules that attack specific genes crucial for cell survival.

“Assassin Molecules”

Brain cells in particular are vulnerable to the cell death caused by small interfering RNAs. Cancer cells are also highly susceptible, which is thought to be the reason why Huntington’s disease patients have such a low incidence of cancer.

A research team at Northwestern University tested these so-called “assassin molecules” on human and mouse cancer cells, including brain, breast, colon and ovarian, that were grown in a laboratory. The small interfering RNAs killed all cancer cells from both humans and mice.

Researchers were encouraged that the treatment also showed no toxicity to healthy cells. Further testing is underway to find a more targeted form of delivery.

Targeted Cancer Treatment at Issels®

Our individually developed, non-toxic immunotherapy programs focus on destroying cancer cells and their environment while sparing healthy tissues. Contact us for more information about cancer vaccines and other targeted cancer treatment protocols at Issels®.

Oncolytic Virus in Research May Herald a Cancer Vaccine for the Future

Immunotherapy brings breakthroughs to cancer treatment.
Immunotherapy brings breakthroughs to cancer treatment.

Promising new cancer treatment research by UC San Francisco has uncovered a cancer killing virus. The vaccine-like effect of the virus harbors potential for use with cancer immunotherapy treatment options, killing some cancer cells directly, and prompting a widespread immune system response to cancer cells far beyond the region the virus infects.

Tremendous Potential
Bringing surprising insight, this new research digs deeper into how oncolytic (cancer-killing) viruses can cooperate with the immune system in attacking cancer cells and tumors. Currently in clinical trials, it points to opportunities in the realm of immunotherapy combination therapies – therapies specifically devised to unleash the full cancer fighting potential of the immune system.

Researchers likened such oncolytic viruses as the equivalent of a bomb, jarring the immune system into action and resuscitating the immune response.

How Do They Work?
Researchers are still coming to terms with fundamentals, which seem to indicate cancer killing viruses attack cancer cells in a number of different ways:

-Through direct infection.
-Via the release of tumor-specific proteins, which trigger a widespread immune response to cancer cells.
-By destroying the blood supply tumors required to survive.

Why a Virus?
Cancer researchers have been exploring the idea of oncolytic viruses since the early 20th century, after observing dramatic remissions following some viral infections. They’ve been actively developing these viruses since the 1980s. With the FDA’s approval and release of oncolytic viral therapy Imlygic (T-Vec) in 2015, such treatment modalities are quickly coming to the forefront of up-and-coming therapy options.

Searching for a new approach to cancer treatment? Contact Issels® to discover more about our non-toxic immunotherapy treatment options that are available today.