Category Archives: News

Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment

Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment
Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment

Many women do not trust the health care system and will often forgo radiation and drug therapy after breast cancer surgery. That is according to a survey of 2,700 breast cancer patients by researchers at Johns Hopkins University. Lead author of the survey, Lorraine Dean, said over 30 percent skip treatments that are intended to kill any cancer cells that remain after surgery.

Contact Issels® for information on how combining conventional treatments with immunotherapy cancer treatment reduces the likelihood of relapse.

Doctor-patient trust is crucial

Cancer is a devastating disease and it is understandable that patients experience feelings of helplessness. It’s not just women with breast cancer who are losing trust in doctors and the health care system, it’s the general public as well. People often feel that doctors put their own financial interest ahead of patient care. When patients feel their doctors don’t listen to them or take their concerns seriously, trust begins to erode.

For the best possible outcome, it is necessary that doctors and patients have a strong bond of trust. Patients should feel comfortable being fully honest with health care providers and the doctors should always remember that a patient’s trust in them is a vital and necessary component of proper medical care. Each person’s cancer is unique and treatment should be based on the specific needs of each patient.

Personalized cancer treatment

At Issels®, we have been practicing individualized treatment for more than 60 years. We want you to make informed decisions about your cancer treatment options. Contact us today for more information on our autologous (from the patient’s own blood) non-toxic cancer treatment protocols.

Drug Resistant Cancer Cells Appear to Share a Similar Weakness

Medical Research Has Validated that Immunotherapy Works to Fight Cancer
Medical Research Has Validated that Immunotherapy Works to Fight Cancer

Cancer researchers at UC San Francisco have discovered a common gene vulnerability in certain treatment-resistant cancers. This is yet another promising advancement that could lead to better treatment of existing cancers and a new approach to preventing cancer recurrences.

Visit Issels® for more information on how combining traditional cancer treatments with integrative immunotherapy can reduce the incidence of relapse from 13 to 50 percent.

Understanding drug-resistant cancer cells

For many years, oncologists thought the drug resistance of cancer cells evolved genetically. Doctors thought a few of the cells survived cancer treatment because they had or somehow developed gene mutations to withstand traditional treatments. These remaining cells would then lead to a recurrence of cancer.

In 2010, researchers working at the Massachusetts General Hospital Cancer Center found that some cancer cells may be able to avoid the effects of treatment without any genetic mutations. These small clumps of cells are called “persister cells” and they go into a dormant state, allowing them to survive cancer drugs. The cells awaken later and lead to new cancer growth.

Exploiting persister cell weaknesses

Matthew Hangauer, PhD led the UC San Francisco study. He said persister cancer cells have a mesenchymal-like gene expression signature and rely on the enzyme glutathione peroxidase 4 (GPX4) to survive treatment. Lab tests show that blocking GPX4 can kill the persister cells found in many different cancer types. Researchers hope to soon validate their findings with human patients.

The Issels® non-toxic cancer treatment

Our caring and knowledgeable experts have helped many patients achieve long-term remission from cancer by using personalized immunotherapy treatment protocols. Contact us for more information.

Gold Nano Particles May Boost Lung Cancer Treatment

Gold Nano-particles Can be Introduced into the Bloodstream to Help Fight Cancer.
Gold Nano-particles Can be Introduced into the Bloodstream to Help Fight Cancer.

Gold may have a value that goes well beyond financial gain. Researchers have discovered that the shiny element can enhance the effectiveness of drugs used to treat lung cancer.

Cancer Treatment as Good as Gold

Testing was conducted at the University of Edinburgh, where Scientists took nanoparticles, which are microscopic particles of gold, and encased them in a chemical device. The object was then used on zebrafish to successfully accelerate their chemical reactions.

Dr. Asier Unciti-Broceta from Cancer Research U.K.’s Edinburgh center participated in the study. He explained that the team’s goal was to find a way to reduce side effects of current chemotherapy methods.

Lessening the Side Effects of Traditional Cancer Treatment

Side effects of cancer treatment are usually the result of drugs attacking healthy cells as well as diseased ones. According to Dr. Unciti-Broceta, their findings indicate that gold could possibly be used to safely release drugs inside tumors.

Immunotherapy for cancer is effective because it helps the immune system’s ability to target cancer cells while sparing healthy tissue. Researchers are continuing tests with nanoparticles in the hopes of applying a similar method with humans.

Dr. Aine McCarthy, also of Cancer Research U.K., expressed optimism that incorporating gold in immunotherapy for cancer could improve the outlook for hard-to-treat cancers such as brain tumors.

Issels®: The Gold Standard of Immunotherapy for Cancer

Our integrative cancer treatment programs are personally tailored for each patient to include methods that complement each other for maximum effectiveness. Contact us today to learn more about our distinguished history of treating patients with all forms of cancer.

What’s Happening in Colorectal Cancer Research?

 

Cancer Research is Making Progress Every Day. Here is the Latest for Colorectal Cancer.
Cancer Research is Making Progress Every Day. Here is the Latest for Colorectal Cancer.

Colorectal cancer is the third most common cancer diagnosed in the United States, but there are currently more than one million survivors in the country. The National Foundation for Cancer Research has some information you should know about this preventable disease.

Rates and Risks of Colorectal Cancer

• Overall risks of developing colorectal cancer are marginally higher for men. Approximately one in 21 is diagnosed with the disease, while the numbers for women are one in 23.

• Health factors that increase the risk of colorectal cancer include inflammatory bowel disorders, family history and genetics, and personal history of polyps or another form of cancer.

• Poor lifestyle choices such as smoking, obesity and high-fat diets, heavy alcohol use and physical inactivity also contribute to colorectal cancer risk.

Regular screenings can help prevent colorectal cancer.

Colorectal Cancer Research in the News

Genomics and immunotherapy for cancer are the main focus points of today’s colorectal cancer research.

• Dr. Wei Zhang and his NFCR-funded team are continuing their promising studies into biomarkers and their use in improving colorectal cancer prognosis and predicting responses to treatment.

• NFCR has also supported the work of Dr. Yung-Chi Cheng, who is on the cusp of producing one of the first FDA-approved oral herbal immunotherapies for cancer. When applied in combination with chemotherapy, PH906 has been found to ease gastrointestinal side effects that accompany treatment for colon and rectal cancers.

Personally Developed Immunotherapy for Cancer at Issels®

Our integrative, non-toxic cancer treatment programs are powerful and effective, but they avoid the often painful side effects of traditional treatments. Contact us for more information.

The First in 10 Years – FDA Approves New Liver Cancer Drug

FDA Approves New Drug! Could This Make Groundbreaking Progress?
FDA Approves New Drug! Could This Make Groundbreaking Progress?

In November 2007, the Food and Drug Administration gave its first-ever approval for a drug designed as liver cancer treatment. Nearly 10 years later, the FDA has given its approval to a second drug for liver cancer that also has applications for some forms of gastrointestinal cancer.

The Search for Effective Liver Cancer Treatment

Sorafenib, brand name Nexavar®, was the original drug approved for treatment of hepatocellular carcinoma (HCC), which is the most common form of liver cancer. The drug acts as a kinase inhibitor to block enzymes responsible for cell division and reproduction.

According to Dr. Tim Greten of NCI’s Center for Cancer Research, since 2007 there have been a number of phase III trials for possible liver cancer treatments. Until now, none of them have been successful.

A 10-Year Breakthrough

Regorafenib, brand name Stivarga®, is also a kinase inhibitor. During a phase III trial, 573 patients whose HCC had not responded to sorafenib were assigned to receive either regorafenib or a placebo.

The patients who received regorafenib experienced an overall three-month increase in survival over the placebo group. Percentage of patients whose tumors had at least partial shrinkage was 11 percent and four percent respectively.

Researchers are also studying the use of other immunotherapy agents against liver cancer. The current focus is on checkpoint inhibitors such as tremelimumab and nivolumab.

Issels®: The Leader in Immunotherapy for All Forms of Cancer

Our individually created immunotherapy programs have helped patients with stage IV HCC and other forms of tumors in all stages. Visit our website to find out why Issels® is ahead of the curve with integrative, non-toxic cancer treatment.

New Blood Test May Identify Early Cases of Pancreatic Cancer

Tests Have Found Blood Can Help Identify Signs of Pancreatic Cancer.
Tests Have Found Blood Can Help Identify Signs of Pancreatic Cancer.

While pancreatic cancer is relatively rare in the United States, it’s one of the more deadly forms of the disease. According to a recently published study, a new blood test may be able to detect pancreatic cancer during its earliest and most treatable stages.

Solving the Puzzle of Early Detection

Experts predict that pancreatic cancer will become the second leading cause of cancer deaths by 2020. The main problem is late detection, with five-year survival rates coming in at less than 10 percent.

Scientists working on methods of early detection ran into a catch-22. Studies to identify potential markers relied on tumor samples from patients who were already in advanced stages of pancreatic cancer.

A Biomarker Breakthrough

The recent study was conducted by a joint University of Pennsylvania/Mayo Clinic team. Senior investigator Dr. Ken Zaret explained that reprogrammed cells were transplanted into mice, where they developed into invasive pancreatic tumors.

Samples from the lesions and tumors were then taken from the mice and used to identify proteins they secreted. Elevated levels of one protein, called THB52, was found to accurately distinguish between the affected and healthy controls, as well as between pancreatic cancer and other forms.

Dr. Zaret and his team are continuing their research with larger samples and more cross-validation. Researchers are hopeful that their work will lead to a viable test for people at high risk for pancreatic cancer.

Immunotherapy for Cancer at Issels®: Treatment for All Stages

We have used personalized immunotherapy for cancer programs to successfully treat patients with all forms of cancer in early and late stages. Contact us for more information.