Category Archives: Cancer Research

Watchful Waiting – A New Treatment for Some Breast Cancer Patients

New Treatment for Breast Cancer
New Treatment for Breast Cancer

Despite significant improvements in cancer treatment, such as the development of immuno-oncology, patients often have a knee-jerk reaction to a cancer diagnosis. This may be particularly true for women, who are mindfully watching the efforts to increase public awareness of breast cancer. They may feel that there are mixed messages in the news in regards to the appropriate treatment for their breast cancer.

Some women, along with their physicians, have begun taking a path that may seem counterintuitive. They are choosing to defer traditional treatments, such as chemotherapy and lumpectomy, in favor of a course often referred to as “watchful waiting.”

What is watchful waiting?

Desiree Basila, a 60 year-old woman diagnosed with DCIS or stage 0 breast cancer, participated in a clinical trial that exemplifies watchful waiting. She began taking tamoxifen, a drug that blocks estrogen, which can often cause tumors to grow. In addition, she visited her doctor twice a year for checkups that alternated between mammograms and MRIs.

The reasons behind watchful waiting

  • Studies show that women with DCIS have a mortality rate of three percent regardless of their form of treatment, which corresponds to the average for the general population.
  • Each case of breast cancer is unique based on a woman’s biological profile, meaning treatment should be determined on an individual basis rather than using a cookie-cutter approach.
  • Mastectomy, radiation and other aggressive treatments sometimes cause seriously harmful side effects that may have been avoided with a more moderate approach.

Assessment of a patient’s individual lifestyle, genetic profile and personal needs has always been a part of our immuno-oncology protocols at Issels®. Visit our website to learn more about our innovative and non-toxic cancer treatment programs.

New Support for Cancer Treatment During Pregnancy

Happy mother, father and daughter in the park
Keeping Baby Safe Even With Cancer

Patients who receive a cancer diagnosis have some difficult choices to make regarding treatments such as chemotherapy or immuno-oncology. Pregnant women have two lives to consider, placing additional weight on their decision for cancer treatment. Is there any option that will not pose significant risk to the fetus?

Some doctors recommend erring on the side of caution, suggesting a preterm delivery or even termination. The results of a study that was presented at the recent European Cancer Conference in Vienna show that cancer treatment may not necessarily interfere with a healthy, full-term pregnancy.

Dr. Frédéric Amant of the Katholieke Universiteit Leuven in Belgium was the lead author of the study, which involved more than 100 children born to women who underwent cancer treatment within the last two trimesters of their pregnancy. Results revealed no difference in cardiac and cognitive functions between these children and those in the control group.

Since birth defects are most likely to occur during the first trimester, none of the women participating in the study received treatment during that period. Premature delivery was found to have a greater impact on fetal development than cancer treatment. Each additional week in the womb added two points to a child’s score on the Bayley Scales of Infant Development, which was used in conjunction with a neurological exam to measure results.

Our non-toxic immuno-oncology therapies at Issels® are personalized to account for lifestyle and other elements of your individual situation. Visit our website for more information about our innovative, state-of-the-art treatments as well as testimonials from our patients.

Cancer Treatments May Affect Nutrition – What to Know

Food is Life
Food is Life

Food is life. You’ve heard these three simple words many times, but if you’ve been diagnosed with cancer they take on a whole deeper meaning. Ironically, the disease can interfere with nutrition at the time you need it most. Use these helpful guidelines to create a healthy eating plan with your doctor.

Why good nutrition is a valuable weapon against cancer

Food is more than just fuel to run your body’s engine. Nutrients in your diet protect and renew tissue cells, maintain your weight for maximum strength, and boost your immune system. A well-balanced diet improves quality of life and may even aid your chances of recovery.

Cancer can alter the digestive process

Certain tumors, especially those found in the stomach or intestines, produce chemicals that limit absorption of nutrients. While you might feel that you’re ingesting a sufficient amount of calories and nutrients, your body may not be able to use them fully.

Side effects of cancer and its treatment can affect appetite and eating

It’s not usual for cancer patients to experience vomiting, diarrhea, dysphagia (difficulty with swallowing), and other side effects that disrupt eating and prevent healthy snacking, particularly when undergoing treatment. Psychological effects like depression and anxiety can also reduce appetite.

Discuss any diet and nutrition concerns with your doctor

Don’t get discouraged if you have problems getting enough food and nutrients. Medicine and other therapies are available to help you meet your nutritional needs.

Our non-toxic immuno-oncology therapies are personalized to incorporate your individual lifestyle elements, including diet and nutrition, environment and genetic predisposition. Visit our website to learn more about the Issels® difference.

New Advance in Pancreatic Cancer Treatment Just in Time for Pancreatic Cancer Awareness Month

New Understanding of Pancreatic Cancer
New Understanding of Pancreatic Cancer

Pancreatic cancer can be difficult to treat with conventional methods, such as chemotherapy. With this form of cancer on the rise, researchers have been working on developing other forms of treatment that might be more effective. Recent developments have led to a new type of treatment for pancreatic cancer that is showing promise as a highly successful way to boost survival rates.

Irreversible Electroporation

Researchers have come up with a treatment that delivers small yet strong electrical bursts that destroy pancreatic cancer cells, which is known as irreversible electroporation (IRE). These electrical bursts create holes in the cells, which leads them to die off. The use of this type of treatment has been associated with a survival rate that nearly doubles for those who also undergo a traditional form of treatment, such as chemo-radiotherapy. IRE is able to affect cancer cells while leaving noncancerous tissue around those cells unharmed, which can lower the risk of side effects and complications.

Researchers are planning on testing IRE in clinical trials to better determine its effectiveness for those with pancreatic cancer. The current study that was conducted involved 200 adults who were diagnosed with Stage III pancreatic cancer. While roughly half of those participants ended up with complications after undergoing IRE, these effects were considered minimal. Researchers found that the average survival rate for study participants was two years, although some lived for up to seven years.

If you would like more information on our non-toxic forms of treatment for pancreatic cancer, please contact the Issels® Center for Integrative Immuno-Oncology. We offer immunotherapy and other types of alternative cancer treatments.

Research on Polar Organisms May Shed New Light on Effective Cancer Treatment

New Research on Polar Organisms
New Research on Polar Organisms

Cryobiology is the study of how low temperatures affect living things. It has been around for thousands of years and lead to many life-saving procedures like cryopreservation of organs at low temperatures for transplant. Immunotherapy has been around for over one hundred years and is used by Issels® immuno-oncology to successfully treat many types of cancer. While transplant organs are stored at cool temperatures, blood, semen and many thin tissues can be maintained practically indefinitely via liquid nitrogen cryopreservation at sub-freezing temperatures. Many living organisms can survive long periods below freezing.

Understanding how some micro-organisms are thriving in the harsh Polar Regions may help researchers develop new cancer treatment techniques.

Arctic study of bacteria may provide new cancer treatments

Shiv Mohan Singh is a cryobiologist and senior researcher with Goa’s National Center for Antarctic and Ocean Research. As a member of India’s first expedition to the Arctic back in 2007, Singh has been studying how some organisms develop survival mechanisms to endure the harsh climate.

They have found that bacteria in Arctic glaciers survive by producing anti-freeze proteins, opening up possible applications in the cryopreservation of blood and organs. One substance that is of particular interest is thelebolan, a derivative from an Antarctic fungus, which has been shown to stall tumor cell growth and induce cell death in cancer lines.

When modern insights and innovations are applied to sciences that have been around for many years, incredible advancements are made in medical treatments. Issels® immuno-oncology uses highly personalized immunotherapy and other non-toxic alternative treatments for cancer. Visit our news blog for the latest advancements in cancer research and contact us to learn more about our integrative immunotherapy treatments.

What Are Tumor Markers and Why Are They Important?

Tumor Markers
Tumor Markers

Not all cancers behave the same way or produce identical markers. Some people with the same type of cancer will have higher levels of tumor markers while others with that cancer will not have the elevated levels. At the Issels® Immuno-Oncology Centers, we understand that highly personalized immunotherapy is often the best approach to achieve long-term remission.

What are tumor markers?

These markers are substances that are produced by the actual cancer itself or other healthy cells in the body when cancer is present. They may also occur in response to some noncancerous conditions. For example, a benign tumor may result in tumor markers.

While the most commonly recognized markers are proteins found in the stool, urine, blood, or other tissue sample from the person, changes to DNA and altered gene expression are starting to be used as tumor markers. Currently, there are over 20 unique tumor markers identified and used for the detection, research and treatment of cancer.

Why they are important?

In addition to helping doctors assess the effectiveness of treatment, tumor markers are measured after treatment has ceased to see if the cancer has returned. Tumor markers may one day be useful in detecting cancer while it is still in its early stages. Because there is not one “universal” tumor marker, they sometimes occur in noncancerous conditions, and may vary based on individual factors.

You can read about the latest cancer treatment breakthroughs by following the Issels news blog. Contact Issels® Center for Integrative Immuno-Oncology to learn more about our non-toxic, personalized immunotherapy cancer treatment protocols.