Alternative Cancer Treatment, Cancer Research, Immuno-Oncology, Immunotherapy

Higher Genetic Mistakes in Tumors May Predict a Better Result for Immunotherapy Treatment

Immunotherapy Can Expand Options for Those With Limited Cancer Treatment Options
Immunotherapy Can Expand Options for Those With Limited Cancer Treatment Options

For many patients with difficult-to-treat tumors, immunotherapy for cancer has successfully expanded their previously limited options. According to a study recently presented at the American Society of Clinical Oncology conference, a new immunotherapy drug has shown promise for treatment of advanced bladder cancer.

The Power of Checkpoint Inhibitors

Researchers speaking at the ASCO conference in Chicago last June reported on the results of clinical trials for atezolizumab, marketed under the name Tecentriq. Atezolizumab is one of a growing number of treatments referred to as checkpoint inhibitors.

Cancer cells often get a foothold by flying under the radar of immune cells, which are your body’s main line of defense against bacteria, viruses and other “invaders.” Checkpoint inhibitors target a molecule called PD-L1, thereby releasing immune cells to attack and kill the rogue cancer cells.

Tumors with “High Mutational Burden” Respond to Immunotherapy

A follow-up analysis to the bladder cancer trials indicated that tumors with a “high mutational burden,” which refers to the number of genetic faults in the cells, appear to be more receptive to immunotherapy. Dr. Jonathan Rosenburg of the Memorial Sloan Kettering Cancer Center in NYC explained that it was made easier for the immune system to identify the mutated cells in such tumors.

Issels®: A Leader in Immunotherapy for Cancer

Our state-of-the-art non-toxic immunotherapy treatments have been used successfully on patients with all forms of cancer, including bladder, breast and melanoma. Visit our website to learn more about our cancer vaccines, gene-targeted therapies and other protocols individually designed to address your specific needs.

Alternative Cancer Treatment, News

Thyroid Cancer the 8th Most Common Cancer in the United States

Thyroid Cancer Most Likely Occurs in Middle Aged Women, But Can Affect Anyone at Any Age
Thyroid Cancer Most Likely Occurs in Middle Aged Women, But Can Affect Anyone at Any Age

Here at Issels®, we treat many types of cancer with immunotherapy, including thyroid cancer. Thyroid cancer diagnoses have risen over the last 30 years and it is now the 8th most common cancer in the United States.

Role of the Thyroid

The thyroid gland is found in the front of the throat area and is very important. Its multiple tasks include producing several hormones, which work to control the heart rate and regulate body temperature. The thyroid also aids in controlling the amount of calcium in the bloodstream and regulating metabolism.

Risk Factors

Cancer of the thyroid is most commonly found in middle-aged white females, but it also occurs in both men and women of all ages. It is a slow-growing cancer and is markedly treatable. People with exposure to radiation also have an increased risk of developing thyroid cancer.

Symptoms

A hoarse voice, neck pain and lymph nodes that are enlarged are some of the early signs of thyroid cancer. Thyroid nodules are not common in children or teens but become more prevalent as people get older.

Types

While the papillary and mixed papillary/follicular thyroid cancer is the most prevalent type, there are three other types, including follicular/Hurtle cell, medullary and anaplastic. The most common types are the most curable, with a cure rate of over 97%.

At Issels®, we can help you find the right combination of thyroid cancer immunotherapy treatment that will help you flourish. Contact us to learn more about our immunotherapy cancer treatment breakthrough.

Alternative Cancer Treatment, Cancer Research, Immuno-Oncology, Immunotherapy

Pancreatic Cancer: Hijacking the Immune System to Hide Its Growth

Pancreatic Cancer: Hijacking the Immune System to Hide Its Growth
Pancreatic Cancer: Hijacking the Immune System to Hide Its Growth

With a five-year survival rate of only three percent, pancreatic cancer is one of the more difficult types of cancer to treat. Scientists from Cancer Research UK, in collaboration with scientists from pharmaceutical giant AstraZeneca, recently announced their discovery of a promising method to help defeat these tumors.

Pancreatic Cancer’s “Stealth Attack”

The immune system is your body’s first line of defense against cancer cells and other foreign bodies that threaten your health. In the case of pancreatic cancer, once the cells make it past the initial gauntlet, they move on to hijack parts of the immune system to facilitate their growth.

The UK study, published in Cancer Cell, reported the team’s discovery of CXCR2, which is a protein that serves as the gatekeeper for pancreatic tumors, guarding them from attack by immune cells. Use of an experimental drug that blocks CXCR2 allowed T-cells to enter the tumor, making it more vulnerable to treatment.

Immunotherapy for Pancreatic Cancer

Until now, the shielding process has made pancreatic cancer particularly resistant to immunotherapy. Professor Peter Johnson, chief clinician at Cancer Research UK, said their study suggests that using the new drug in concert with immunotherapy treatments could create “a powerful weapon” in the fight against pancreatic cancer.

Using the Body’s Natural Defenses to Defeat Cancer

For more than 60 years, our Issels® center has been the leader in the use of immunotherapy for pancreatic cancer and many other types. Contact us today for more information about our personalized non-toxic treatments, including cancer vaccines, hyperthermia and gene-targeted therapies.

Alternative Cancer Treatment, Cancer Research, Immunotherapy

Gut Flora and Cancer – the Important Connection

Using Gut Flora in Treatment Has Benefits Comparable to Anti-Cancer Drugs
Using Gut Flora in Treatment Has Benefits Comparable to Anti-Cancer Drugs

When it comes to your health, the term “bacteria” usually inspires a negative reaction. You may be surprised to learn that your body actually harbors “good” bacteria that boosts your immune system and plays a role in preventing cancer.

The Role of Gut Flora

Your body’s microbiome is a network containing trillions of organisms such as bacteria, fungi and viruses. Some are positive and some are not, but they all work together to maintain a balance that keeps your system in good working condition.

In the late 1990s, scientists began to discover the crucial value of the group of organisms centered in your colon, referred to as “gut flora.” Research has found that healthy gut flora contributes to a strong immune system, which is your body’s first line of defense against foreign organisms that cause illness and disease.

Gut Flora and the Fight against Cancer

Cancer cells can often evade detection by your body’s immune system, allowing them to grow unchecked. Traditional therapies such as radiation and chemotherapy are effective, but they end up destroying healthy cells as well.

Researchers from the University of Chicago, encouraged by positive results from testing on mice, included gut flora as part of integrative immunotherapy treatments. The successful results were comparable to the beneficial effects of anti-cancer drugs.

State-of-the-Art Integrative Immunotherapy at Issels®

Integrative immunotherapy programs used at Issels® are focused on harnessing your body’s own natural defenses to destroy cancer cells. Visit our website to learn more about our cancer vaccines, immune enhancement protocols and other personalized non-toxic treatments.

Cancer Care Tips, Immunotherapy, News

National Cancer Institute Launches Mole vs Melanoma Info Site

Are You at Risk for Skin Cancer?
Are You at Risk for Skin Cancer?

It’s important to understand the difference between common moles that often occur on the skin and melanomas. To the untrained eye, the two can look very similar, and they can result in people either worrying unnecessarily about the condition of their skin or overlooking skin irregularities that require immediate medical attention.

At Issels®, we’ve worked with many people who have been diagnosed with melanoma, and immunotherapy has been shown to be a very promising alternative to traditional cancer treatments. Even so, identification remains a serious challenge, and the National Cancer Institute has come up with a tool to help.

The Moles to Melanoma Tool

The Moles to Melanoma tool from the National Cancer Institute provides individuals with pictures that help to understand the three types of moles that can appear on the human body. They are:

  • Common Moles
  • Dysplastic Nevi (or DN)
  • Melanoma

Common moles are those that are non-cancerous, and their characteristics are not a cause for concern. Dysplastic Nevi moles are those that aren’t cancerous, but that possess qualities that would cause doctors to keep an eye on them for any changes that could indicate melanoma. Finally, melanoma is characterized by moles that fit into the ABCDE category of identification.

Are You Concerned About Melanoma?

If your family has a history of melanoma, or if you have moles that cause you to be concerned, this tool can be very useful for you. However, it’s important to remember that no diagnostic tool should ever take the place of a professional diagnosis from an experienced physician.

At Issels, melanoma can be treated with non-toxic melanoma immunotherapy. Contact us to learn more.

Cancer Care Tips, Immuno-Oncology, News

July is Bladder Cancer Awareness Month – Do You Know the Bladder Cancer Risk Factors?

Men Are More Likely to Get Bladder Cancer Than Women... Are You at Risk?
Men Are More Likely to Get Bladder Cancer Than Women… Are You at Risk?

This July, you may see people sporting a yellow ribbon for Bladder Cancer Awareness Month. What do you know about the risks for this type of cancer that accounts for five percent of all new diagnoses in the United States each year?

Demographic Factors

  • Bladder cancer is the fourth most common type of cancer in men. According to projections by the American Cancer Society, in 2016 new diagnoses of bladder cancer in men will outnumber women three to one.
  • Approximately 90 percent of bladder cancer occurs in people over the age of 55.
  • Caucasians are twice as likely as African-Americans and Hispanics to develop bladder cancer. Occurrences are also lower in Asian-Americans and American Indians.

Lifestyle Factors

  • Smoking is the most serious risk factor, tripling your chances of developing bladder cancer. In addition, roughly half of all bladder cancer cases with both men and women are caused by smoking.
  • The diabetes medicine Actos, along with certain dietary supplements, has been linked to an increased risk of bladder cancer.

Medical Factors

  • Previous chemotherapy or radiation treatment can increase your risk of developing bladder cancer.
  • While direct cause-and-effect of bladder cancer has not yet been established, a link has been found with chronic urinary tract infections or bladder and kidney stones.

Issels® Offers Non-Toxic Immunotherapy for Bladder Cancer

Patients at Issels® have been successfully treated with immunotherapy for bladder cancer as well as other common forms such as lung cancer, breast cancer and melanoma. Contact us to learn more about our cancer vaccines and other personalized, integrative treatment programs.

Individualized Cancer Treatment